anti-Angiomotin Like 2 (AMOTL2) Antibodies

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Additionally we are shipping Angiomotin Like 2 Kits (4) and Angiomotin Like 2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AMOTL2 51421 Q9Y2J4
AMOTL2 56332 Q8K371
AMOTL2 65157  
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Top anti-Angiomotin Like 2 Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of AMOTL2 Antibody in A375 cell line lysates (35ug/lane) Western blot analysis of AMOTL2 Antibody in mouse liver tissue lysates (35ug/lane) 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of AMOTL2 using anti-AMOTL2 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human placenta tissue lysates.After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-AMOTL2 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for AMOTL2 at approximately 95KD. The expected band size for AMOTL2 is at 86KD. 100 μg 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg 11 to 14 Days
$419.83
Details
Human Rabbit Un-conjugated WB   200 μL 11 to 16 Days
$658.43
Details
Human Rabbit APC ELISA, WB   200 μL 16 Days
$814.00
Details
Human Rabbit FITC ELISA, WB   200 μL 16 Days
$814.00
Details
Human Rabbit HRP ELISA, WB   200 μL 16 Days
$814.00
Details
Human Rabbit PE ELISA, WB   200 μL 16 Days
$814.00
Details
Human Rabbit Un-conjugated WB   50 μg 9 to 11 Days
$449.29
Details
Human Rabbit Un-conjugated ELISA, IF, WB   100 μg 6 to 7 Days
$532.46
Details

More Antibodies against Angiomotin Like 2 Interaction Partners

Human Angiomotin Like 2 (AMOTL2) interaction partners

  1. these results provide novel insights into a dual tumor suppressive function of AMOTL2 by targeting both YAP and AKT in liver size control and cancer prevention

  2. study reports for the first time that USP9X is a deubiquitinase of Angiomotin-like 2 (AMOTL2) and that AMOTL2 mono-ubiquitination is required for YAP inhibition

  3. mTORC2-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP signaling.

  4. AmotL2 expression correlates with loss of tissue architecture in tumors from human breast and colon cancer patients.

  5. Scaffold proteins angiomotin (Amot) and angiomotin-related AmotL1 and AmotL2 were recently identified as negative regulators of YAP and TAZ by preventing their nuclear translocation.

  6. These results collectively suggest that the Hippo pathway negatively regulates the actin-binding activity of Amot family members through direct phosphorylation.

  7. These results demonstrate a role for Amotl2 in synaptic maturation and support the involvement of podosomes in this process.

  8. AMOTL2 interacts with TAZ and modulates transcriptional activity of TAZ.

  9. AMOTL2 is as a novel activator of LATS2.

  10. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

Mouse (Murine) Angiomotin Like 2 (AMOTL2) interaction partners

  1. mTORC2-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP signaling.

  2. AmotL2 disrupts apical-basal cell polarity and promotes tumor invasion.

  3. Amot, Amotl1, and Amotl2 are differentially expressed in uterine cells during the peri-implantation period.

  4. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

  5. Data show that MUPP1 interacts with angiomotin (Amot), JEAP/Amot-like 1 and MASCOT/Amot-like 2, and that all the Amot/JEAP family proteins also interacted with Patj, a close relative of MUPP1.

Angiomotin Like 2 (AMOTL2) Antigen Profile

Protein Summary

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family.

Gene names and symbols associated with AMOTL2

  • angiomotin like 2 (AMOTL2) antibody
  • angiomotin-like 2 (Amotl2) antibody
  • angiomotin like 2 (Amotl2) antibody
  • angiomotin like 2 (amotl2) antibody
  • angiomotin like 2b (amotl2b) antibody
  • AW549739 antibody
  • C79691 antibody
  • Lccp antibody
  • MASCOT antibody
  • mKIAA0989 antibody
  • zgc:154007 antibody

Protein level used designations for AMOTL2

Leman coiled-coil protein , angiomotin-like protein 2 , angiomotin like 2 , angiomotin-like protein 2-like , angiomotin like 2b

GENE ID SPECIES
51421 Homo sapiens
56332 Mus musculus
65157 Rattus norvegicus
718868 Macaca mulatta
100379727 Xenopus (Silurana) tropicalis
100523696 Sus scrofa
460712 Pan troglodytes
100540953 Meleagris gallopavo
559784 Danio rerio
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