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ANTXR2 encodes a receptor for anthrax toxin. Additionally we are shipping ANTXR2 Antibodies (64) and ANTXR2 Proteins (21) and many more products for this protein.
Showing 2 out of 12 products:
A decreased CMG2 expression is a negative prognostic factor for soft tissue sarcoma patients.
Results identified Gly116Val mutation in ANTXR2 associated with hyaline fibromatosis syndrome.
Stability of domain 4 of the anthrax toxin protective antigen and the effect of the VWA domain of CMG2 on stability
expression does not affect cytotoxicity to anthrax toxin
study examines 4 cases with clinical features of hyaline fibromatosis syndrome; identified a previously unreported splice junction mutation (c.946-2A-->G in intron 11) and a recurrent founder mutation ( c.1074delT)
This study reports a novel association between ANTXR2 and ankylosing spondylitis in the Han Chinese.
Case Report: systemic hyalinosis with a heterozygous mutation in CMG2.
The association between ANTXR2 rs4333130 and ankylosing spondylitis was independent of HLA-B27 status. Clinical disease severity scores (BASDAI and BASFI) and pain score were higher in ANTXR2 rs4333130 CT genotype.
Roles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore Formation
Anthrax Susceptibility: Human Genetic Polymorphisms Modulating ANTXR2 Expression
miR-124 might induce autophagy to participate in AS by targeting ANTXR2, which might be implicated in pathological process of AS.
The disulfide bond Cys255-Cys279 in the immunoglobulin-like domain of ANTXR2 is required for membrane insertion of anthrax protective antigen pore.
CMG2 glycosylation provides a buffer towards genetic variation by promoting folding of the protein in the ER lumen.
Results show that CMG2 has been shown to be able to regulate the proliferation and tubule formation of endothelial cells, but not the migration.
Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene.
data suggested that cellular cholesterol regulated ANTXR2-dependent activation of MMP-2 via ERK1/2 phosphorylation in neuroglioma U251 cell.
Fused the ANTXR2 ectodomain to the C-terminus of bacterial Trigger Factor (TF), and the fusion protein was overly expressed as a dominant soluble protein in E coli.
Silencing CMG2 using targeted siRNAs provided almost complete protection against anthrax lethal toxin-induced cytotoxicity and death in murine and human macrophages.
Loss of CMG2 expression is associated with breast cancer progression.
A protective antigen mutation increases the pH threshold of anthrax toxin receptor 2-mediated pore formation
Antxr2a functions as a Wnt-dependent polarized determinant, which, through the action of RhoA and zDia2, exerts torque on the spindle to align it with the animal-vegetal axis.
This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.
capillary morphogenesis gene 2 protein
, capillary morphogenesis protein 2
, anthrax toxin receptor 2