Anti-Thyroid-Globulin Antibody (TGAB) ELISA Kits

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland.

list all ELISA KIts Gene Name GeneID UniProt
TGAB 7038 P01266
TGAB    
TGAB    
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Top Anti-Thyroid-Globulin Antibody ELISA Kits at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Mouse 0.625 U/mL 1.25-20 U/mL Typical standard curve 96 Tests 13 to 16 Days
$910.56
Details
Human 1.875 ng/mL 3.125-200 ng/mL Typical standard curve 96 Tests 12 to 14 Days
$630.00
Details
Rabbit 1.0 ng/mL 10-250 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Guinea Pig 1.0 ng/mL 10-250 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Rat 1.0 ng/mL 10-250 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Pig 1.875 ng/mL 3.125-200 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Chicken 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Monkey 1.0 ng/mL 10-250 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Dog 1.0 ng/mL 10-250 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Sheep
  96 Tests 15 to 18 Days
$707.14
Details

More ELISA Kits for Anti-Thyroid-Globulin Antibody Interaction Partners

Human Anti-Thyroid-Globulin Antibody (TGAB) interaction partners

  1. Study shows that TH is downregulated in papillary thyroid carcinoma.

  2. The purpose of the present study was to identify and characterize new mutations in the TG gene.

  3. this study shows that monogenic Hashimoto thyroiditis is associated with a variant in the thyroglobulin gene

  4. A novel rare missense mutation in the TG gene was identified. The ChEL domain is critical for protein folding and patients with congenital hypothyroidism due to misfolded TG may present without low serum TG despite the TG gene mutations.

  5. High thyroglobulin expression is associated with mediastinal lymph node and lung metastases in thyroid cancer.

  6. Thyroglobulin determination in fine needle aspiration biopsy washout of suspicious lymph nodes can be used in the diagnosis of recurrent papillary thyroid carcinoma.

  7. Positive preoperative serum TgAb is associated with worse primary tumour characteristics but rarely showed poor prognosis, probably due to more aggressive treatment of these subjects.

  8. Single nucleotide polymorphisms in the TG gene were associated with the development of Hashimoto's disease and Graves' disease, the intractability of Graves' disease, and the levels of TG mRNA expression, serum TG, and serum anti-thyroglobulin antibody.

  9. Data suggest iodination of TG is involved in regulation of NIS expression in thyroid follicle via TSH/TSHR signaling; NIS expression and PKA activity are up-regulated by lowly iodinated TG; NIS expression is down-regulated and PKC activity up-regulated by highly iodinated TG. (TG, thyroglobulin; NIS, sodium/iodide symporter; PK, protein kinase; TSH, thyroid-stimulating hormone; TSHR, thyroid-stimulating hormone receptor)

  10. Data show that the cutoff value for thyroglobulin measurement with fine-needle aspiration (Tg-FNA) was higher in patients with thyroids than in patients without thyroids.

  11. findings proved that iodinated TG in thyroid follicular lumen regulated TTF-1 and PAX8 expression through thyroid stimulating hormone/thyroid stimulating hormone receptor (TSH/TSHR) mediated cAMP-PKA and PLC-PKC signaling pathways.

  12. Data (including data from studies using knockout mice) suggest that thyrotropin/thyrotropin receptor signal transduction stimulates thyroglobulin phosphorylation and contributes to enhanced de novo triiodothyronine formation in thyrocytes.

  13. Multiple factors should be taken into consideration when evaluating Tg as a marker of ID in adult populations, and the Tg results may depend on the assay used. Still, Tg is a sensitive marker of ID

  14. Biallelic TG mutations most commonly underlie severe congenital hypothyroidism.

  15. Mutations in Thyroglobulin gene is associated with metastasis in Thyroid Cancer.

  16. Mutations in the genes for thyroglobulin and thyroid peroxidase cause thyroid dyshormonogenesis and autosomal-recessive intellectual disability

  17. Patients with low-and intermediate-risk differentiated thyroid carcinoma could be considered cured when their serum thyroglobulin levels were changed 6-12 months after thyroid ablation.

  18. The system is characterized by a very high sensitivity and specificity allowing the ex-vivo detection of sub ng/ml concentrations of human Thyroglobulin from needle washouts of fine-needle aspiration biopsies of thyroid nodule from different patients.

  19. 22 rare non-polymorphic variants including six truncating variants and 16 missense variants of unknown significance in Chinese patients with congenital hypothyroidism.

  20. Data suggest that primary functions of TG include iodide storage and thyroid hormonogenesis; combinations of nonsense mutations, frameshift mutations, splice site mutations, and missense mutations in TG occur spontaneously to cause congenital hypothyroidism and thyroidal endoplasmic reticulum stress. [REVIEW]

Anti-Thyroid-Globulin Antibody (TGAB) Antigen Profile

Antigen Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Gene names and symbols associated with TGAB

  • thyroglobulin (TG) antibody
  • AITD3 antibody
  • TGN antibody
GENE ID SPECIES
7038 Homo sapiens
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