Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) ELISA Kits

Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. Additionally we are shipping APOH Antibodies (166) and APOH Proteins (38) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
APOH 11818 Q01339
APOH 350 P02749
APOH 287774  
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Top APOH ELISA Kits at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 2 to 3 Days
$374.00
Details
Rat 7 ng/mL 28-1800 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$788.33
Details
Mouse 1.42 ng/mL 3.12 ng/mL - 200 ng/mL 96 Tests Log in to see 13 to 16 Days
$682.11
Details
Cow 3.13 ng/mL n/a   96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Dog 2.34 ng/mL n/a   96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Rabbit 1.0 ng/mL 50-1000 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 1.0 ng/mL 50-1000 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$616.00
Details
Chicken 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$616.00
Details
Pig
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced APOH ELISA Kits

  1. Human APOH ELISA Kit for Sandwich ELISA - ABIN6730893 : Lackner, Beck, Eichmeir, Gemeiner, Hummel, Pullirsch, Razzazi-Fazeli, Seifner, Miller: Contamination of therapeutic human immunoglobulin preparations with apolipoprotein H (?2-glycoprotein I). in Electrophoresis 2014 (PubMed)

  2. Human APOH ELISA Kit for Sandwich ELISA - ABIN2683481 : Kim, Park, Heo, Moon, Park: Plasma apolipoprotein H levels are different between aspirin induced respiratory diseases and aspirin tolerant asthma. in Pulmonary pharmacology & therapeutics 2014 (PubMed)

More ELISA Kits for APOH Interaction Partners

Mouse (Murine) Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) interaction partners

  1. During the parasite's hepatic replication, the C-terminal region of EXP-1 binds ApoH. This molecular interaction plays a pivotal role for successful Plasmodium liver-stage development. Down-regulation of ApoH expression in either hepatic cells or mouse livers by RNA interference resulted in impaired intrahepatic development.

  2. A1-A1, which is a soluble analog of ApoER2 that binds pathological beta2GPI/anti-beta2GPI complexes, has a positive impact on hemodynamics in lupus-prone mice with spontaneous anti-beta2GPI antibodies and hypertension

  3. These results suggested that CRP/oxidized low density lipoprotein/beta 2-Glycoprotein I complexes may induce lipid accumulation and inflammation in macrophages via the p38/MAPK and NFkappaB signaling pathways.

  4. TLR2 increase the stimulating effect of beta2GP1/anti-beta2GP1 complex on the expression of TNF-alpha in mouse peritoneal macrophages

  5. The Fifth Domain of Beta 2 Glycoprotein I Protects from Natural IgM Mediated Cardiac Ischaemia Reperfusion Injury.

  6. These results indicate that both NF-kappaB and c-Jun/AP-1 are involved in regulating anti-beta2GPI-induced expression of prothrombotic and proinflammatory molecules in vivo.

  7. Phospholipid scramblase 1 regulates phosphatidylserine exposure in response to oxygen stress, leading to beta2-glycoprotein I and IgM binding and lipid-mediated, inflammatory responses.

  8. beta2-GPI-D-I-tDCs may offer a novel approach for developing therapy for APS patients

  9. Data suggest that factors enabling a beta2-glycoprotein I (beta2GPI)-reactive T cell response may predispose individuals to the development of systemic lupus erythematosus (SLE)-related autoantibodies

  10. Deletion of beta2 GPI accelerates and potentiates the autoimmune phenotype in male BXSB.Yaa mice

  11. beta2-glycoprotein I-derived peptides attenuate injury and inflammation when administered in a therapeutic manner in intestinal ischemia/reperfusion injury.

  12. Interaction of beta2-glycoprotein I with lipopolysaccharide leads to Toll-like receptor 4 (TLR4)-dependent activation of macrophages

  13. beta2GPI binding to EC requires priming with pro-inflammatory factors which is not needed for uterine and placental localization probably dependent on hormonal changes.

  14. gene knock-out mice display enhanced B16 melanoma development and tumor microvessel density

  15. Endothelial cell incubation with anti-lysobisphosphatidic-acid MoAb or with patients' IgG resulted in antibody binding to late endosomes and caused beta2GPI redistribution and accumulation in perinuclear vesicular structures reminiscent of late endosomes.

  16. Data are consistent with pathogenic mechanisms in antiphospholipid syndrome involving both neutralization of beta(2)-glycoprotein I (beta(2)GPI) function and beta(2)GPI-immunoglobulin complex formation.

  17. beta-2-glycoprotein 1 plays an important physiologic role in the recognition of dying cells

  18. certain subpopulations of antibodies raised against tetanus toxoid and cross-reactive with beta(2)GPI, because of the molecular mimicry mechanism, could have pathologic potential

  19. These results are compatible with a role for apolipoproteins in lipid metabolism and transport in the developing lung in association with the sex difference in surfactant lipid synthesis.

Human Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) interaction partners

  1. Our study delineates the role of beta2GPI in murine septicaemia though not in murine sepsis, however our preliminary patient data suggest that examining the role of beta2GPI in sepsis models in the future is a reasonable avenue to pursue.

  2. This study aimed to explore the mechanism of a novel mutation (p.Lys38Glu) in apolipoprotein H (APOH) gene causing hereditary beta2-glycoprotein I (beta2GPI) deficiency and thrombosis in a proband with thrombophilia.

  3. Data suggest alpha-1-antitrypsin (A1AT) and APOH (beta-2-glycoprotein-1) could represent promising markers for renal carcinogenesis in Von Hippel-Lindau disease (VHLD) patients.

  4. Suggest that anti-beta2 GPI antibodies bind to beta2 GPI-PS complexes expressed on microparticles. Consequent loss of beta2 GPI-PS expression on MPs may impair scavenging and contribute to the accumulation of circulating PS-negative MPs, a possible source of autoantigens in systemic lupus erythematosus.

  5. the data revealed that reduced beta2GPI exerts protective effects from glucoseinduced injury in human umbilical cord vein endothelial cells.

  6. Data suggest that, in patients with anti-GPIIb/IIIa-mediated immune thrombocytopenia, diminished plasma levels of beta2-GPI are linked to enhanced complement activation.

  7. The aim of this study was to assess clinical utility of the anti-Domain 1 B2GP1 antibodies in the diagnosis and risk stratification of antiphospholipid syndrome. Anti-Domain 1 test does not add accuracy in predicting Antiphospholipid syndrome thrombotic complications on the top of accuracy offered by classic tests.

  8. we have demonstrated a pathogenic role for aPL containing samples, mediated via aPL-2bGPI interactions, resulting in activation of the pro-apoptotic p38 MAPK pathway.

  9. Pretransplant IgA-aB2GP1 was the main risk factor for graft thrombosis and early graft loss after renal transplantation.

  10. These results suggest that antibodies directed against domain 1 of beta-2-glycoprotein 1 may contribute to antiphospholipid syndrome risk assessment, due to their association with the diagnosis of systemic autoimmunity and with more aggressive triple antiphospholipid antibody profiles, such as triple positivity and lupus anticoagulant activity.

  11. Circulating Immune Complexes of IgA Bound to Beta 2 Glycoprotein are Strongly Associated with the Occurrence of Acute Thrombotic Events.

  12. Genome-wide significant results in or near the APOH gene on chromosome 17 have been found for plasma apolipoprotein H levels in middle-aged and older adults.

  13. Prevalence and pathogenicity of IgA aB2GPI antibodies may vary from a population of ESRD patients to another.

  14. The association of IL28B and APOH single nucleotide polymorphisms (SNPs) with sustained virological response and of ITPA SNPs with anemia related phenotypes.

  15. We identified APOH as an obesity-resistance gene that interacts with FTO rs9939609 to more than double the occurrence of thinness.

  16. Trp316Ser variant (rs1801690) near the apolipoprotein H (beta2-glycoprotein-I) gene was associated with serum lipid parameters in Chinese volunteers. Suggest that there may be have racial/ethnic-and/or gender-specificity.

  17. Using affinity chromatography, polymyxin B can effectively decrease the binding of beta2GP1 to immobilize phosphatidylserine.

  18. Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitor-based therapy.

  19. The renoprotective and antifibrosis effects of beta2GPI and reduced beta2GPI on diabetic nephropathy were closely associated with suppressing the activation of the TGF-beta1-p38 MAPK pathway.

  20. Apo H is up-regulated in aspirin-tolerant asthma (ATA) compared to aspirin-exacerbated respiratory disease (AERD) and normal controls, suggesting that Apo H may be involved in different pathogenesis of ATA from AERD

APOH Antigen Profile

Antigen Summary

Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.

Gene names and symbols associated with APOH

  • apolipoprotein H (apoh) antibody
  • apolipoprotein H (APOH) antibody
  • apolipoprotein H (Apoh) antibody
  • APOH antibody
  • B2G1 antibody
  • B2GP1 antibody
  • B2GPI antibody
  • beta-2-GPI antibody
  • beta2-GPI antibody
  • BG antibody
  • LOC100227913 antibody

Protein level used designations for APOH

apolipoprotein H , apolipoprotein H (beta-2-glycoprotein I) , APC inhibitor , activated protein C-binding protein , apo-H , beta(2)GPI , beta-2-glycoprotein 1 , beta-2-glycoprotein I , B2GPI , anticardiolipin cofactor

GENE ID SPECIES
496631 Xenopus (Silurana) tropicalis
718645 Macaca mulatta
100227913 Taeniopygia guttata
11818 Mus musculus
100339267 Oryctolagus cuniculus
350 Homo sapiens
403945 Canis lupus familiaris
281006 Bos taurus
287774 Rattus norvegicus
417431 Gallus gallus
468459 Pan troglodytes
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