Aquaporin 3 (Gill Blood Group) Proteins (AQP3)

AQP3 encodes the water channel protein aquaporin 3. Additionally we are shipping AQP3 Antibodies (175) and AQP3 Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AQP3 11828 Q8R2N1
AQP3 65133 P47862
AQP3 360 Q92482
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Top AQP3 Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50 to 55 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Escherichia coli (E. coli) Cow Un-conjugated   5 applications 1 to 2 Days
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg 11 to 18 Days

AQP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Rat (Rattus)
Human , ,

Top referenced AQP3 Proteins

  1. Human AQP3 Protein expressed in HEK-293 Cells - ABIN2714852 : Choi, Kim, Choi: Profiles of hypothalamus-pituitary-interrenal axis gene expression in the parr and smolt stages of rainbow trout, Oncorhynchus mykiss: effects of recombinant aquaporin 3 and seawater acclimation. in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2015 (PubMed)

More Proteins for Aquaporin 3 (Gill Blood Group) (AQP3) Interaction Partners

Zebrafish Aquaporin 3 (Gill Blood Group) (AQP3) interaction partners

  1. The mutated amino acid residues in the dominant alleles line the pore surface of Aqp3a and influence pore permeability.

  2. Enhanced water and cryoprotectant permeability of porcine oocytes after artificial expression of human and zebrafish aquaporin-3 channels.

Mouse (Murine) Aquaporin 3 (Gill Blood Group) (AQP3) interaction partners

  1. The results of this study suggest that skin AQP3 expression decreases in diabetes, which may limit water transport from the vessel side to the corneum side, causing dry skin.

  2. This study may provide new insights into therapeutic approaches for schizophrenia by regulating AQP3 expression, which is associated with paranodal disruption

  3. increased expression with hyperosmolarity associated with notochordal cell to small nucleus pulposus cell differentiation

  4. results support a novel role for AQP3 in modulating renal injury and suggest the mechanisms involved in protection against hypoxic injury.

  5. The results of this study suggest that NAR relieves Lop-induced constipation by increasing the levels of interstitial cells of Cajal markers (c-Kit and SCF), as well as AQP3. Thus, NAR may be effective as a candidate in patients suffering from lifestyle-induced constipation.

  6. Increased expression of AQP3 and AQP10 in murine skin with the concomitant presence of an inflammatory stimulus (IMQ) and contact with detergent-containing water increases skin acanthosis and affects the biology of keratinocytes.

  7. AQP3(-/-) mice showed impaired healing of superficial wounds in the colon and impaired mucosal innate immune responses against Citrobacter rodentium infection.

  8. These results imply a critical role of AQP3 in asthma.

  9. This study found that both the airway epithelial cells of AQP3-knockout mice and AQP3-knockdown HBECs exhibited an obviously impaired self-healing capacity with defective epithelial cell migration through AQP3-facilitated glycerol transport.

  10. Decreased glycerol efflux from the skeletal muscles in AQP3 knockout mice may result in low exercise capacity.

  11. treatment of human HepG2 cells with TCDD also increased the expression of AQP3 mRNA and protein

  12. AQP3-facilitated H2O2 transport is required for NF-kappaB activation in keratinocytes in the development of psoriasis.

  13. Studied the effect of the total tannins extract of rhubarb on expression od aquaporin 2 and auqaporin 3 in diarrhoea mice.

  14. AQP3 has a pro-differentiative role in epidermal keratinocytes and PLD2 activity is necessary for this effect.

  15. analysis of the molecular link between the circadian clock and AQP3 function in mouse dorsal skin and HaCaT cells

  16. In a mouse model of intestinal ischemia the level of miR-874 expression was inversely related to AQP3 protein expression.

  17. Data indicate selective expression of aquaporins 3 and 8 in primitive erythroblasts and aquaporins 1 and 9 in adult definitive erythroblasts.

  18. We therefore suggest that AQP3-mediated H(2)O(2) uptake is required for chemokine-dependent T cell migration in sufficient immune response.

  19. It was concluded that acyl-CoA binding protein via aquaporin 3 is necessary for intact urine concentrating ability through efflux over the basolateral membrane of the collecting duct.

  20. The results of this study suggest that Gypsum fibrosum plays an important role in the increased levels of cutaneous AQP3 expression enhanced by Byakkokaninjinto.

Human Aquaporin 3 (Gill Blood Group) (AQP3) interaction partners

  1. LMP2A induced the phosphorylation of ERK, which activated DNMT3a transcription and caused AQP3 expression loss through CpG island methylation of AQP3 promoter.

  2. Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3.

  3. In conclusion, decreased AQP3 expression might play a role in the pathogenesis of vitiligo and acral vitiligo skin differs from non-acral skin in showing gradual fading of AQP3 expression through the epidermis and weaker AQP3 expression in the stratum spinosum in perilesional compared to lesional biopsies.

  4. circHIPK3 regulated xenograft tumor growth via the miR-124-AQP3 axis.

  5. our study demonstrated that AQP3 was downregulated in SSc dermal fibroblasts compared with healthy dermal fibroblasts.

  6. AQP 3 is downregulated in bullous pemphigoid patients

  7. AQP3 is probably associated with endometrial receptivity and may serve as a marker for the implantation window in vitro. AQP3 may affect uterine endometrial receptivity through ovarian steroid hormone-induced motility.

  8. AQP3 expression is positively correlated with Helicobacter pylori infection status and the progression of gastric mucosal diseases

  9. The AQP3 gene polymorphism is associated with a susceptibility to EBVaNPC and EBVaL, and the homozygous AA genotype is more frequently observed in individuals who develop EBVaNPC and EBVaL.

  10. the present data suggest that expression of AQP3 and 5 may be a marker for distinguishing between patients with dry mouth and those with Sjogren's syndrome

  11. Expression of AQP3 was markedly upregulated and miR-488 was significantly upregulated in osteosarcoma (OS) tissues and cell lines. miR488 inhibited the proliferation, invasion and epithelial-mesenchymal transition (EMT) of OS cells by directly downregulating AQP3 expression, and miR488 targeting AQP3 was responsible for inhibition of the proliferation, invasion and EMT of OS cells.

  12. TFF peptides promptly produced at sites of injury increase AQP levels, most notably AQP3, thereby enhancing the cells' ability to rapidly change their shape as part of the restitutive process. TFF peptides also require functioning AQP3 channels to induce cell migration.

  13. an altered expression of placental AQP3 may produce failures in placentation such as in preeclampsia.

  14. Data show that AQP3 is localized largely in the cytoplasm and can be targeted to the plasma membrane in prostate cancer cells via a cAMP/PKA/RalA pathway.

  15. placental expression reduced in pre-eclampsia

  16. AQP1, 3 and 5 expression through the stages of human salivary gland morphogenesis, was examined.

  17. In response to injury, AQP3-depleted colonic epithelial cells showed defective lamellipodia, focal adhesions, and repair after wounding, along with impaired H2O2 responses after exposure to the intestinal pathogen Citrobacter rodentium.

  18. AQP3 siRNA and PLD2 siRNA significantly downregulated the mRNA and protein levels of AQP3 and PLD2 in the A431 cells; inhibiting proliferation and promoting apoptosis in vitro.

  19. Reduced epidermal AQP-3 may have a role in impaired melanocyte survival in vitiligo, and might be a potential negative biological marker for vitiligo activity

  20. provide evidence for the involvement of the JNK pathway in AQP3 regulation in isolated oligohydramnios tissues in vitro, in amniotic epithelial cells derived from normal amniotic fluid and fluid from patients with isolated oligohydramnios

Cow (Bovine) Aquaporin 3 (Gill Blood Group) (AQP3) interaction partners

  1. Our findings suggest that AQP3 and AQP7 are possibly involved in the tolerance to freeze-thawing in bull spermatozoa, particularly in the sperm's tail.

  2. Data suggest that AQP3 is localized to mid-piece of bull spermatozoa; AQP7 is localized to mid-piece and post-acrosomal region of bull spermatozoa. Neither relative abundance of AQP3 or AQP7 nor their localization patterns is altered by cryopreservation; individual differences between bull ejaculates appear to be common. Abundance of AQP7 is higher in ejaculates with good versus poor freezability in cryopreservation.

  3. Data suggest that expression of AQP3 (aquaglyceroporin-3) in rumen mucosa can be modulated by dietary factors; here, AQP3 and UT-B (urea transporter B) expression are upregulated with solid food intake (low-protein diet of plant forage) at weaning.

  4. lack of AQP3 in bovine erythrocytes points to the lipid pathway as responsible for glycerol permeation and explains the low glycerol permeability and high E(a) for transport observed in ruminants.

Guinea Pig Aquaporin 3 (Gill Blood Group) (AQP3) interaction partners

  1. Aquaporins 1 and 3 were widely expressed in the cochlea and endolymphatic sac of guinea pigs. [AQP1; AQP3]

Pig (Porcine) Aquaporin 3 (Gill Blood Group) (AQP3) interaction partners

  1. although AQP3 is present in boar spermatozoa in two different localisation patterns, neither the AQP3 content nor its localisation have been found to be associated with conventional sperm parameters.

  2. AQP1, AQP2, and AQP3, and V2R expression increased with gestation age in the fetal kidney, suggesting that this induction might contribute to the maturation of urinary concentrating capacity

  3. The full length coding sequences of porcine (Sus scrofa) AQP3, 7 and 9 and the genomic sequence of AQP3 including 6 exons and 5 introns, was cloned.

AQP3 Protein Profile

Protein Summary

This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.

Gene names and symbols associated with AQP3

  • aquaporin 3a (aqp3a)
  • aquaporin 3 (Gill blood group) (AQP3)
  • aquaporin 3 (Tb927.6.1520)
  • aquaporin 3 (MCYG_07750)
  • aquaporin 3 (Aqp3)
  • aquaporin 3 (Gill blood group) (Aqp3)
  • AQP-2 protein
  • AQP-3 protein
  • aqp3 protein
  • GIL protein
  • SAQP3 protein
  • Tb06.28P18.240 protein
  • wu:fa95h06 protein
  • wu:fi13e05 protein
  • zgc:55525 protein

Protein level used designations for AQP3

aquaporin 3 , aquaporin-3 , AQP-3 , aquaglyceroporin-3 , 31.4 kDa water channel protein , aquaporin 3 (GIL blood group) , Aquaglyceroporin-3

406777 Danio rerio
702721 Macaca mulatta
3657787 Trypanosoma brucei brucei strain 927/4 GUTat10.1
9225529 Arthroderma otae CBS 113480
11828 Mus musculus
65133 Rattus norvegicus
100344959 Oryctolagus cuniculus
360 Homo sapiens
780866 Bos taurus
443047 Ovis aries
100723824 Cavia porcellus
100126235 Sus scrofa
611792 Canis lupus familiaris
426894 Gallus gallus
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