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ALOX5AP encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Additionally we are shipping ALOX5AP Antibodies (63) and ALOX5AP Proteins (5) and many more products for this protein.
Showing 5 out of 10 products:
Human ALOX5AP ELISA Kit for Sandwich ELISA - ABIN810595
van der Laan, Foroughi Asl, van den Borne, van Setten, van der Perk, van de Weg, Schoneveld, de Kleijn, Michoel, Björkegren, den Ruijter, Asselbergs, de Bakker, Pasterkamp: Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study. in Atherosclerosis 2015
Show all 2 Pubmed References
ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin (show INS ELISA Kits) Resistance
Data indicate that a single amino acid mutation was sufficient to reverse the speciation observed in wild type 5-Lipoxygenase activating protein (FLAP).
BRP (show GDF5 ELISA Kits)-7 potently suppresses leukotriene biosynthesis by interacting with FLAP in mouse peritonitis model.
FLAP regulates phosphorylation of tau protein via modulating GSK-3beta activity.
This study demonistrated that a a novel role for FLAP in the pathogenesis of anxiety-like behavior in mice.
Deletion of myeloid cell FLAP markedly attenuates the proliferative response to vascular injury, while preserving endothelial integrity.
A FLAP inhibitor given during critical window periods may prevent oxygen induced aberration of pulmonary alveolarization in a dose- and time-dependent manner.
the 5-LO (show ALOX5 ELISA Kits) pathway emerges early during embryonic stem cell differentiation into cells of the myeloid lineage
Adipose tissue from obese mice, compared with that from lean mice, exhibited increased 5-LO (show ALOX5 ELISA Kits) activating protein
Data show that 5-lipoxygenase (show ALOX5 ELISA Kits) activity increases during senescence-like growth arrest via a p53 (show TP53 ELISA Kits)/p21-dependent pathway in both human and mouse embryo fibroblasts.
No significant association was found between ALOX5AP rs10507391 polymorphism and ischemic stroke risk in males. Moreover, ALOX5AP rs10507391 polymorphism was not associated with cardioembolic ischemic stroke risk.
rs17222919 of ALOX5AP is a potential genetic protective factor against ischemic stroke in the Chinese population
This study revealed that epistatic interaction among the ALOX5 (show ALOX5 ELISA Kits), ALOX5AP and MPO (show MPO ELISA Kits) genes played a significant role in vulnerability to ischemic stroke.
The results the study indicate that SNP genetic variants of ALOX5AP might play a role in the development of SSc (show CYP11A1 ELISA Kits)-related pulmonary fibrosis and ventilatory dysfunction.
The observation that the coexpression of FLAP with a subset of the 5-LOX (show ALOX5 ELISA Kits) mutants restores 5-LOX (show ALOX5 ELISA Kits)-wild-type (wt)-like levels of products formed in intact cells suggests a physical protein-protein interaction, beyond colocalization, of 5-LOX (show ALOX5 ELISA Kits) and FLAP.
Meta-analysis suggests that the A allele at the ALOX5AP SG13S114 polymorphism is a protective factor for the ischemic stroke in the European population
Genetic polymorphisms of T-1131C APOA5 (show APOA5 ELISA Kits) and ALOX5AP SG13S114 can be considered risk factors for the susceptibility to ischemic stroke in Morocco.
No association was found between single-nucleotide polymorphisms of ALOX5AP or PDE4D (show PDE4D ELISA Kits) and the risk of overall ischemic stroke in a southeastern Chinese population. The ALOX5AP gene might be related to ischemic stroke incidence in females.
Genetic interaction of CD80 (show CD80 ELISA Kits) and ALOX5AP was observed in systemic lupus erythematosus in Asian populations.
ALOX5AP, CPNE3, IL1R2 (show IL1R2 ELISA Kits), IL6 (show IL6 ELISA Kits), TLR2, TLR4 (show TLR4 ELISA Kits), and THY1 (show THY1 ELISA Kits) were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows.
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
arachidonate 5-lipoxygenase-activating protein
, Arachidonate 5-lipoxygenase-activating protein
, MK-886-binding protein
, arachidonate 5 lipoxygenase activating protein
, 5-lipoxygenase-activating protein FLAP
, arachidonate 5-lipoxygenase activating protein
, 5-lipoxygenase-activating protein