anti-Ataxin 7-Like 2 Antibodies

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord.

Data Quality
  • 12
Type
  • 47
    Primary antibodies
Antigen
  • 47
Reactivity
  • 47
  • 29
  • 29
  • 4
  • 4
Application
  • 33
  • 17
  • 15
  • 13
  • 4
Detection Method
  • 3
Host
  • 47
Clonality
  • 47
Binding Specificity
  • 9
  • 9
  • 8
  • 2
  • 2
Conjugate
  • 21
  • 3
  • 3
  • 3
  • 2
  • 2
Isotype
  • 33
  • 2
Format
  • 41
  • 5
Suggested next Filters
47 Products
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN632757
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN632758
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application FACS, WB
Order details Cat. No. ABIN5534922
$550.00
400 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityCow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
Application WB
Order details Cat. No. ABIN2774039
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityCow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
Application WB
Order details Cat. No. ABIN2785259
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, WB
Order details Cat. No. ABIN6258382
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN2705524
$487.50
200 μL
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application EIA, WB
Order details Cat. No. ABIN950578
$522.50
0.4 mL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, WB
Order details Cat. No. ABIN2459636
$550.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityCow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
Application WB
Order details Cat. No. ABIN6741233
$551.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityBat, Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
Application WB
Order details Cat. No. ABIN6743251
$551.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman
Application IHC (p)
Order details Cat. No. ABIN5573201
$577.33
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN2982259
$309.53
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF (p), IHC (p), WB
Order details Cat. No. ABIN2170428
$327.80
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN6710677
$350.00
100 μL
Plus shipping costs $45.00
Delivery in 6 to 11 Business Days
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Ataxin 7-Like 2 (ATXN7L2) Antigen Profile

Protein Summary

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the 'pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with spinocerebellar ataxia-7 contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele. The encoded protein is a component of the SPT3/TAF9/GCN5 acetyltransferase (STAGA) and TBP-free TAF-containing (TFTC) chromatin remodeling complexes, and it thus plays a role in transcriptional regulation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ATXN7L2

  • ataxin 7-like 2 (Atxn7l2) antibody
  • ataxin 7 like 2 (ATXN7L2) antibody
  • ataxin 7-like 2b (atxn7l2b) antibody
  • ataxin 7-like 2a (atxn7l2a) antibody
  • ataxin 7 like 2 (Atxn7l2) antibody
  • 2610528J18Rik antibody
  • atxn7l2 antibody
  • RGD1307047 antibody
  • wu:fi32b11 antibody
  • wu:fi36e12 antibody
  • zgc:92454 antibody
  • zgc:136546 antibody

Protein level used designations for ATXN7L2

ataxin-7-like protein 2 , mFLJ00381 protein , ataxin 7-like 1 , ataxin 7-like 2 , fi32b11

GENE ID SPECIES
72522 Mus musculus
127002 Homo sapiens
310781 Rattus norvegicus
436928 Danio rerio
457092 Pan troglodytes
490121 Canis lupus familiaris
541097 Bos taurus
701498 Macaca mulatta
692316 Danio rerio
100340504 Oryctolagus cuniculus
100581273 Nomascus leucogenys
100619233 Monodelphis domestica
100629633 Equus caballus
100718819 Cavia porcellus
100517342 Sus scrofa