Bactericidal/Permeability Increasing Protein Proteins (BPI)

BPI encodes a lipopolysaccharide binding protein. Additionally we are shipping BPI Antibodies (120) and BPI Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BPI 329547 Q67E05
BPI 671 P17213
BPI 296321 Q6AXU0
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Top BPI Proteins at

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
Escherichia coli (E. coli) Human His tag,GST tag 100 μg 15 to 18 Days
Human Cells Human His tag   50 μg 4 Days
Human Cells Human His tag 100 μg 14 to 16 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Human Cells Human His tag   10 μg 15 to 16 Days
Yeast Rabbit His tag   1 mg 60 to 71 Days
Yeast Cow His tag   1 mg 60 to 71 Days
Human Human Un-conjugated 100 μg 2 to 3 Days

BPI Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
Human , , ,
, ,
Rat (Rattus)

More Proteins for Bactericidal/Permeability Increasing Protein (BPI) Interaction Partners

Pig (Porcine) Bactericidal/Permeability Increasing Protein (BPI) interaction partners

  1. the BPI protein expres-sion levels in the E. coli F18-resistant group were significantly higher than those in the sensitive group, indicating that high BPI protein ex-pression is associated with resistance to E. coli F18

  2. BPI expression is improved by demethylation of the BPI gene upstream CpG island.

  3. The expression of the BPI gene of Sutai piglets ranging from newborn to post-weaning days 8, 18, 30, and 35, was analyzed.

  4. Upregulation of porcine BPI gene expression in the small intestines plays a direct role in resistance to ETEC F18 infection.

  5. In jejunum and duodenum, the expression of BPI gene in resistant pig was significant higher than that in the sensitive pig.

Mouse (Murine) Bactericidal/Permeability Increasing Protein (BPI) interaction partners

  1. Findings suggest that residue Asp190 combined with surrounding positively charged residues largely contribute to bactericidal and endotoxin-neutralizing activities of bactericidal/permeability-increasing protein (BPI) mBPI5.

  2. Data suggest that BPI is expressed in testis and epididymis (but not in seminal vesicles, prostate, or solidification glands); BPI expression in epididymis is up-regulated by testosterone; BPI may participate in process of sperm-oocyte interaction.

  3. The mouse neutrophils store BPI with antibacterial activity and that murine BPI is also expressed in testis and epididymis.

  4. the requirement for C/EBP epsilon in mediating BPI gene expression in myeloid cells in vitro and in vivo.

  5. data demonstrate that murine BPI is a potent LPS-neutralizing protein that may limit innate immune responses during Gram-negative infections

Human Bactericidal/Permeability Increasing Protein (BPI) interaction partners

  1. define BPI as an immune enhancing pattern recognition molecule in Gram-positive infections.

  2. BPI G645A polymorphism was associated with a decreased risk of ulcerative colitis; the BPI G645A polymorphism was not associated with the risk of crohn's disease.

  3. Bactericidal permeability increasing protein Lys216Glu polymorphism is associated with both Crohn's disease and ulcerative colitis.

  4. MPO and BPI in CD4(+)T-lymphocytes, and PDHA1 and MRPL42 in CD8(+) T-lymphocytes might be used as specific biomarkers of severe asthma progression.

  5. This review article focuses on the structural and functional properties of BPI with respect to its antimicrobial contribution to host defense during GNB infections and endotoxin-induced inflammation.

  6. Diminished PRRs, IFN-signature, and BPI gene expression raises the possibility that impairments in these pathways contribute to the susceptibility of LBW term infants to infection.

  7. Lung function and IgA-BPI-ANCA, but not Leeds criteria, were significantly associated with adverse outcome.

  8. BPI mutation (PstI in intron 5) and a decreased plasma BPI level were significant risk factors in susceptibility to COPD...BPI genetic mutation and impaired BPI production or release may result in airflow obstruction in smokers.

  9. The bactericidal/permeability-increasing protein in the innate defence of the lower airways

  10. there is a correlation between the presence of BPI-ANCA, the properties of the colonizing bacteria and the clinical conditions of the host in cystic fibrosis

  11. SNP Lys216Glu is associated with Crohn's disease and ulcerative colities

  12. Restriction enzyme digestion and DNA sequence analysis revealed that the sequence encoding signal peptide and bioactive N-terminal fragment of BPI had six nucleotide substitutions, compared with that of the established human BPI sequence

  13. BPI is the main target antigen for ANCA in tuberculosis and BPI-ANCA increase after treatment

  14. Circulating BPI could constitute a biomarker of lipid metabolism in subjects with normal glucose tolerance and could help to identify those subjects with preserved endothelial function.

  15. Investigated if serum and salivary anti-BPI autoantibodies appear in the course of acute pneumonia. Presence of anti-BPI IgG on admission didn't correlate with inflammatory markers. Salivary anti-BPI IgA didn't appear during the course of acute pneumonia.

  16. Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia

  17. increased levels in fetal disease, premature rupture of membranes, and preterm labor

  18. Constitutive expression of BPI, which increases upon interleukin 4 stimulation, by human dermal fibroblast was demonstrated, suggesting an important role of BPI in gram-negative bacterial clearance and a dampened response to endotoxin in the skin

  19. BPI and cathepsin G are the major antigenic targets of ANCA seen in patients with systemic sclerosis

  20. BPI and HNP are accumulated in the synovial cavity of patients with rheumatoid arthritis

Cow (Bovine) Bactericidal/Permeability Increasing Protein (BPI) interaction partners

  1. Polymorphism in BPI has no effect on daughter yield deviation for somatic cell score in Holstein cattle.

Rabbit Bactericidal/Permeability Increasing Protein (BPI) interaction partners

  1. p15 proteins are stored in the specific (secondary) granules of rabbit neutrophils and are secreted extracellularly after inflammatory stimulation.

  2. The p15 proteins exhibit antimicrobial synergy with another rabbit cathelicidin (CAP-18) and with the rabbit Bactericidal/permeability-increasing protein (BPI).

BPI Protein Profile

Protein Summary

This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms.

Gene names and symbols associated with BPI

  • bactericidal/permeability-increasing protein (BPI)
  • bactericidal permeablility increasing protein (Bpi)
  • bactericidal/permeability-increasing protein (Bpi)
  • bactericidal/permeability-increasing protein S homeolog (bpi.S)
  • 9230105K17Rik protein
  • bpi protein
  • bpi.L protein
  • BPIFD1 protein
  • lbp protein
  • rBPI protein

Protein level used designations for BPI

bactericidal permeability-increasing protein , bactericidal/permeability increasing protein , bactericidal/permeability-increasing protein , BPI fold containing family D, member 1 , CAP 57 , recombinant BPI holoprotein, rBPI , bactericidal/permeability-increasing protein L homeolog , bactericidal/permeability-increasing protein S homeolog , lipopolysaccharide binding pro

100286800 Sus scrofa
329547 Mus musculus
671 Homo sapiens
296321 Rattus norvegicus
280734 Bos taurus
100009228 Oryctolagus cuniculus
100713739 Cavia porcellus
444637 Xenopus laevis
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