anti-C-Type Lectin Domain Family 16, Member A (CLEC16A) Antibodies

CLEC16A encodes a member of the C-type lectin domain containing family.

list all antibodies	Gene Name	GeneID	UniProt
Anti-Human CLEC16A	CLEC16A	23274	Q2KHT3
Anti-Mouse CLEC16A	CLEC16A	74374	Q80U30
Anti-Rat CLEC16A	CLEC16A	287044

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Top anti-CLEC16A Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN4299112	Human	Goat	Un-conjugated	ELISA, WB	0.1 mg	Log in to see	7 to 9 Days	$485.88	Details
ABIN4299113	Human	Rabbit	Un-conjugated	ICC, IF, IHC, IHC (p)	0.1 mL	Log in to see	10 to 13 Days	$491.63	Details
ABIN452846	Human	Rabbit	Un-conjugated	EIA, WB	0.4 mL	Log in to see	6 to 8 Days	$390.50	Details
ABIN238572	Human	Goat	Un-conjugated	ELISA, WB	100 μg	Log in to see	6 to 7 Days	$242.88	Details
ABIN490428	Human	Goat	Un-conjugated	ELISA, WB	100 μg	Log in to see	7 to 9 Days	$610.50	Details
ABIN390971	Human	Rabbit	Un-conjugated	WB	400 μL	Log in to see	10 to 11 Days	$324.50	Details
ABIN5533037	Human	Rabbit	Un-conjugated	WB	400 μL	Log in to see	2 to 3 Days	$515.63	Details
ABIN303843	Bat	Goat	Un-conjugated	ELISA	100 μg	Log in to see	7 to 9 Days	$507.83	Details
ABIN5553632	Human	Goat	Un-conjugated	WB	0.1 mg	Log in to see	8 to 11 Days	$462.00	Details
ABIN2811732	Human	Rabbit	Alexa Fluor 594	IF (p)	100 μL	Log in to see	14 to 21 Days	$405.90	Details

Top referenced anti-CLEC16A Antibodies

Human Polyclonal CLEC16A Primary Antibody for ELISA - ABIN314273 : Hakonarson, Grant, Bradfield, Marchand, Kim, Glessner, Grabs, Casalunovo, Taback, Frackelton, Lawson, Robinson, Skraban, Lu, Chiavacci, Stanley, Kirsch, Rappaport, Orange, Monos, Devoto, Qu et al.: A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. ... in Nature 2007 (PubMed)
Human Polyclonal CLEC16A Primary Antibody for ELISA, WB - ABIN4299112 : Skinningsrud, Husebye, Pearce, McDonald, Brandal, Wolff, Løvås, Egeland, Undlien: Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. in The Journal of clinical endocrinology and metabolism 2008 (PubMed)
Human Polyclonal CLEC16A Primary Antibody for ICC, IF - ABIN4299113 : Wu, Li, Chen, Yan, Jiang, Wu, Shao, Xu, Kang, Huang, Zhu, Ji, Gao: Involvement of CLEC16A in activation of astrocytes after LPS treated. in Neurochemical research 2012 (PubMed)
Human Polyclonal CLEC16A Primary Antibody for WB - ABIN390971 : Li, Jørgensen, Maggadottir, Bakay, Warnatz, Glessner, Pandey, Salzer, Schmidt, Perez, Resnick, Goldacker, Buchta, Witte, Padyukov, Videm, Folseraas, Atschekzei, Elder, Nair, Winkelmann, Gieger et al.: Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells. ... in Nature communications 2015 (PubMed)

More Antibodies against CLEC16A Interaction Partners

Human C-Type Lectin Domain Family 16, Member A (CLEC16A) interaction partners

Data (including data from studies using knockout and transgenic mice/cells) suggest that CLEC16A, NRDP1 (show RNF41 Antibodies), and USP8 (show USP8 Antibodies) form tripartite complex; CLEC16A-NRDP1 (show RNF41 Antibodies)-USP8 (show USP8 Antibodies) complex appears to rely on ubiquitin signals to promote mitophagy and maintain mitochondrial function necessary for beta-cell function. (CLEC16A = C-type lectin domain family 16 member A; NRDP1 (show RNF41 Antibodies) = ubiquitin-protein ligase (show UBE2K Antibodies) NRDP1 (show RNF41 Antibodies); USP8 (show USP8 Antibodies) = ubiquitin specific peptidase 8 (show USP8 Antibodies))
Golgi-associated CLEC16A negatively regulates autophagy via modulation of mTOR (show FRAP1 Antibodies) activity.
Study provides evidence that Clec16a plays a key role in the survival of Purkinje cells and in the degradative function or clearance of autolysosomes.
A possible regulatory role for the multiple sclerosis-associated rs12927355 in CLEC16A.
CLEC16A was found to be a susceptibility factor for SLE, with possible contribution to the development of the disease.
Clec16a knockdown mice showed reduced number of B cells and elevated IgM levels compared with controls.
identify CLEC16A as a pivotal gene in multiple sclerosis that serves as a direct regulator of the human leukocyte antigen class II (show HLA-DRB5 Antibodies) pathway in antigen-presenting cells.
data suggests that two polymorphisms of the CLEC16A gene play an important role in the developing of ACS in men.
This study demonstrated that the Polymorphism, Single Nucleotide of CLEC16A is associated with multiple sclerosis in Russia.
The study suggested that a CLEC16A polymorphism may be protective against Vogt-Koyanagi-Harada syndrome syndrome in a Chinese Han population.

Mouse (Murine) C-Type Lectin Domain Family 16, Member A (CLEC16A) interaction partners

Study provides evidence that Clec16a plays a key role in the survival of Purkinje cells and in the degradative function or clearance of autolysosomes.
CLEC16A associations in common variable immunodeficiency disorder represent the first robust evidence of non-HLA associations in this immunodeficiency condition.
The novel Pdx1 (show PDX1 Antibodies)-Clec16a-Nrdp1 (show RNF41 Antibodies) pathway this study describes provides a genetic basis for the pathogenesis of mitochondrial dysfunction in multiple forms of diabetes.
Islets from mice with pancreas-specific deletion of Clec16a have abnormal mitochondria with reduced oxygen consumption and ATP concentration, both of which are required for normal beta cell function, Clec16a controls beta cell function and prevents diabetes by controlling mitophagy.

CLEC16A Antigen Profile

Protein Summary

This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CLEC16A

C-type lectin domain family 16 member A (CLEC16A) antibody
C-type lectin domain containing 16A (CLEC16A) antibody
C-type lectin domain family 16, member A (clec16a) antibody
C-type lectin domain family 16 member A (clec16a) antibody
C-type lectin domain family 16, member A (Clec16a) antibody
C-type lectin domain containing 16A (Clec16a) antibody

4932416N17Rik antibody
CLEC16A antibody
curt antibody
Gop-1 antibody
KIAA0350 antibody
mKIAA0350 antibody
RGD1305773 antibody

Protein level used designations for CLEC16A

C-type lectin domain family 16, member A , KIAA0350 protein-like , protein CLEC16A-like , protein CLEC16A

GENE ID	SPECIES
416632	Gallus gallus
453918	Pan troglodytes
615054	Bos taurus
711016	Macaca mulatta
100025510	Monodelphis domestica
100056501	Equus caballus
100331886	Danio rerio
100339140	Oryctolagus cuniculus
100407119	Callithrix jacchus
100444305	Pongo abelii
100480433	Ailuropoda melanoleuca
100488730	Xenopus (Silurana) tropicalis
100588518	Nomascus leucogenys
23274	Homo sapiens
74374	Mus musculus
287044	Rattus norvegicus

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Show all anti-C-Type Lectin Domain Family 16, Member A (CLEC16A) Antibodies with Pubmed References

Human C-Type Lectin Domain Family 16, Member A (CLEC16A) interaction partners

Mouse (Murine) C-Type Lectin Domain Family 16, Member A (CLEC16A) interaction partners

Protein Summary

Gene names and symbols associated with CLEC16A

Protein level used designations for CLEC16A