CLEC16A antibody (AA 731-830) (Cy7)

Catalog No. ABIN2807978

This anti-CLEC16A antibody is a Rabbit Polyclonal antibody detecting CLEC16A in WB, FACS, IF (cc) and IF (p). Suitable for Human.

Quick Overview for CLEC16A antibody (AA 731-830) (Cy7) (ABIN2807978)

Target: CLEC16A (C-Type Lectin Domain Family 16, Member A (CLEC16A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC16A antibody is conjugated to Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CLEC16A Antibody (Cy7)

Binding Specificity: AA 731-830

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLEC16A

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CLEC16A

Target: CLEC16A (C-Type Lectin Domain Family 16, Member A (CLEC16A))

Alternative Name: CLEC16A

Background:

Synonyms: Gop-1, KIAA0350, Protein CLEC16A, C-type lectin domain family 16 member A, CLEC16A

Background: Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.

Gene ID: 23274

UniProt: Q2KHT3