CD177 Molecule (CD177) ELISA Kits

NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971 [PubMed 5552408]).[supplied by OMIM, Mar 2008].. Additionally we are shipping CD177 Antibodies (129) and CD177 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CD177 57126 Q8N6Q3
Anti-Rat CD177 CD177 499099  
CD177 68891 Q8R2S8
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Top CD177 ELISA Kits at

Showing 2 out of 10 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.225 ng/mL 0.9-60 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Mouse 5.86 pg/mL 23.44-1500 pg/mL   96 Tests Log in to see 15 to 18 Days

More ELISA Kits for CD177 Interaction Partners

Human CD177 Molecule (CD177) interaction partners

  1. Characterization of the CD177 interaction with the ANCA antigen proteinase 3 responsible for autoimmune diseases has been reported.

  2. our results have highlighted for the first time an up-regulated transcriptomics and phenotypic expression of neutrophil CD177 in septic shock patients compared to healthy volunteers.

  3. CD177 signals in a beta2 integrin-dependent manner to orchestrate a set of activation-mediated mechanisms that impair human neutrophil migration.

  4. Data show that CD177 protein is monoallelically expressed in neutrophils and neutrophil-differentiated hematopoietic stem cells (HSCs).

  5. Abundance of CD177hi neutrophils correlates with homozygosity for CD177 reference allele, while heterozygosity for ectopic CD177P1 gene conversion correlates with increased CD177neg neutrophils, in which both CD177P1 partially incorporated allele and paired intact CD177 allele are transcribed

  6. Data indicate that high percentage of CD177 antigen-positive neutrophils undergo dynamic change during sepsis.

  7. the CD177 SNP is the primary genetic determinant for HNA-2 deficiency and expression variations. The mechanistic delineation of HNA-2 genetics will enable the development of genetic tests for diagnosis and prognosis of HNA-2-related human diseases.

  8. This is the first report showing a prognostic correlation between CD177 expression and solid tumor behavior.

  9. Skewed low neutrophil CD177(%) is highly associated with clonal myeloid disorders, particularly myelodysplasia, and may be useful for detecting clonal myeloid disorders.

  10. CD177/PECAM-1 adhesive interaction, while contributing to neutrophil-endothelial cell interaction in neutrophil transendothelial migration, does not contribute to or is redundant in platelet-neutrophil interactions

  11. PRV1 overexpression is associated with Essential Thrombocythemia and Myelofibrosis.

  12. NB1-proteinase 3 interactions may play a role in aiding neutrophil transmigration.

  13. pivotal role of the NB1-Mac-1 receptor interaction for PR3-ANCA-mediated neutrophil activation

  14. The increased membrane expression of PR3 found in ANCA-associated systemic vasculitis is not linked directly to circulating PR3 or PR3 gene transcription, but is dependent upon CD177 expression and correlated with the transcription of the CD177 gene.

  15. heterophilic PECAM-1/CD177 interactions affect the phosphorylation state of PECAM-1 and endothelial cell junctional integrity in such a way as to facilitate neutrophil transmigration in a previously unrecognized allele-specific manner.

  16. Testins for PRV-1 expression is useful in the diagnosis of essential thrombocythaemia, but not in the diagnosis of polycythaemia vera.

  17. biochemical characterization; overexpressed in polycythemia rubra vera

  18. overexpression of PRV-1 to discrimitate essential thrombocythemia and polycythemia vera from secondary thrombocytosis and secondary erythrocytosis

  19. No evidence for a PRV-1 gene rearrangement was found in metaphase or interphase cells in polycythemia vera and thus, overexpression of PRV-1 in granulocytes in PV is related to mechanisms that do not involve structural genetic changes.

  20. review of gene structure, gene expression, polymorphisms, and relevance to diseases

Mouse (Murine) CD177 Molecule (CD177) interaction partners

  1. Herein we established a novel genetic mouse model to study the role of CD177 and found that CD177 plays an important role in neutrophils.

CD177 Antigen Profile

Antigen Summary

NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971

Gene names and symbols associated with CD177 Molecule (CD177) ELISA Kits

  • CD177 molecule (CD177) antibody
  • CD177 molecule (Cd177) antibody
  • CD177 antigen (Cd177) antibody
  • 1190003K14Rik antibody
  • CD177 antibody
  • HNA-2a antibody
  • HNA2A antibody
  • MGC157159 antibody
  • NB1 antibody
  • NB1 GP antibody
  • Pdp3 antibody
  • PRV-1 antibody
  • PRV1 antibody
  • RGD1562941 antibody

Protein level used designations for CD177 Molecule (CD177) ELISA Kits

CD177 antigen , NB1 glycoprotein , cell surface receptor , human neutrophil alloantigen 2a , polycythemia rubra vera 1 , polycythemia rubra vera protein 1 , CD177 molecule , CD177 antigen-like

57126 Homo sapiens
499099 Rattus norvegicus
616350 Bos taurus
100453048 Pongo abelii
68891 Mus musculus
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