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The protein encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. Additionally we are shipping CD207 Proteins (9) and CD207 Kits (5) and many more products for this protein.
Showing 10 out of 126 products:
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786754 : Arizon, Nudel, Segev, Mizraji, Elnekave, Furmanov, Eli-Berchoer, Clausen, Shapira, Wilensky, Hovav: Langerhans cells down-regulate inflammation-driven alveolar bone loss. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed) Show all 46 Pubmed References
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786758 : Abadie, Badell, Douillard, Ensergueix, Leenen, Tanguy, Fiette, Saeland, Gicquel, Winter: Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes. in Blood 2005 (PubMed) Show all 46 Pubmed References
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786755 : Bachy, Hervouet, Becker, Chorro, Carlin, Herath, Papagatsias, Barbaroux, Oh, Benlahrech, Athanasopoulos, Dickson, Patterson, Kwon, Geissmann, Klavinskis: Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed) Show all 46 Pubmed References
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786756 : Bobr, Olvera-Gomez, Igyarto, Haley, Hogquist, Kaplan: Acute ablation of Langerhans cells enhances skin immune responses. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed) Show all 46 Pubmed References
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786757 : Boyd, Bennuru, Wang, Sanprasert, Law, Chaussabel, Nutman, Semnani: Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion. in Infection and immunity 2013 (PubMed) Show all 46 Pubmed References
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786759 : Bigley, Haniffa, Doulatov, Wang, Dickinson, McGovern, Jardine, Pagan, Dimmick, Chua, Wallis, Lordan, Morgan, Kumararatne, Doffinger, van der Burg, van Dongen, Cant, Dick, Hambleton, Collin: The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. in The Journal of experimental medicine 2011 (PubMed) Show all 32 Pubmed References
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786762 : Bonetti, Bacci, Santosuosso, Mazzanti, Aldinucci, Ballerini, Guasti, Calosi, Bosi, Romagnoli: Rosiglitazone promotes the differentiation of Langerhans cells and inhibits that of other dendritic cell types from CD133 positive hematopoietic precursors. in Histology and histopathology 2014 (PubMed) Show all 32 Pubmed References
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786763 : Debeer, Le Luduec, Kaiserlian, Laurent, Nicolas, Dubois, Kanitakis: Comparative histology and immunohistochemistry of porcine versus human skin. in European journal of dermatology : EJD 2013 (PubMed) Show all 32 Pubmed References
Human Monoclonal CD207 Primary Antibody for IHC (fro), FACS - ABIN786760 : de Jong, de Witte, Taylor, Geijtenbeek: Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed) Show all 32 Pubmed References
Human Monoclonal CD207 Primary Antibody for ICC, FACS - ABIN786761 : Eisenwort, Jurkin, Yasmin, Bauer, Gesslbauer, Strobl: Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-?1-dependent human epidermal Langerhans cells. in The Journal of investigative dermatology 2011 (PubMed) Show all 32 Pubmed References
Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent
Data show that Candida albicans and Candida tropicalis preferentially localized in (and persisted within) a sub- population of Peyer's patch Langerin-positive dendritic cells.
Langerin is expressed by the XCR1(+) "DC1" populat (show CD1C Antibodies)ion of mice.
Langerin+ dermal dendritic cells appear to be site- and strain-specific
TLR7 (show TLR7 Antibodies)-activated langerin(neg (show TMEM131 Antibodies)) dendritic cells trigger psoriatic plaque formation via IL-23 (show IL23A Antibodies)-mediated activation of innate IL-17 (show IL17A Antibodies)/IL-22 (show IL22 Antibodies)-producing lymphocytes, independently of IFN-I.
model of epicutaneous ovalbumin (show OVA Antibodies) sensitization inducing an inflammatory skin resembling atopic dermatitis (AD) to explore the role of CD207 in the pathogenesis of AD
Langerin-positive dendritic cells appear to be the predominant, though not exclusive, population responsible for in vivo transport of anti-DEC-205 (show LY75 Antibodies) antibodies from the skin to the draining lymph nodes in steady state and inflammation.
Data demonstrated that CD207(+) CD8alpha(+) thymic DCs do not share a common origin with T cells but originate from intrathymic precursors.
The normal corneal epithelium is endowed with CD11c (show ITGAX Antibodies)(+) Langerin+ cells that are LCs, whereas the stroma is endowed with a separate population of (non-LC) Langerin+ DCs.
Comparable T helper 1 (Th1 (show HAND1 Antibodies)) and CD8 (show CD8A Antibodies) T-cell immunity by targeting HIV gag p24 to CD8 (show CD8A Antibodies) dendritic cells within antibodies to Langerin, DEC205 (show LY75 Antibodies), and Clec9A (show CLEC9A Antibodies).
CD207(+)CD1a (show CD1A Antibodies)(+) cells are circulating in patients with active Langerhans cell histiocytosis, and TSLP (show TSLP Antibodies) and TGF-beta (show TGFB1 Antibodies) are potential drivers of Langerhans-like cells in vivo.
the data provide evidence that human Langerhans cells are able to cross-present antigens after langerin-mediated internalization.
Calcium-independent activation of an allosteric network in langerin by heparin oligosaccharides has been reported.
Kinetic and Structural Studies of Interactions between Glycosaminoglycans and Langerin
We suggest that CD207 gene polymorphisms rs13421115 and rs17718987 increase the risk of development of end-stage renal disease.
This study shows that mutations in the Langerin gene are present in the analysed populations at different genotypic and allelic frequencies and further studies should be conducted to verify the role of these mutations in HIV-1 susceptibility.
This study is the first to demonstrate that langerin represents an authentic receptor that binds and internalizes influenza A virus to facilitate infection.
Data suggest that Langerin (CD207)-mediated binding of Yersinia pestis to antigen-presenting cells (APCs (show APCS Antibodies)) may promote its dissemination and infection.
Langerin binds heparin (HEP)-like oligosaccharides in two different binding sites depending on the ligand size.
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
CD207 molecule, langerin , CD207 antigen, langerin , C-type lectin domain family 4 member K , Langerhans cell specific c-type lectin , langerin , C-type lectin domain family 4, member K , CD 207 antigen