The protein encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa.
CD207 Antigen Profile
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Gene names and symbols associated with CD207
CD207 molecule (CD207) antibody
CD207 antigen (Cd207) antibody
CD207 molecule (Cd207) antibody
Protein level used designations for CD207
CD207 molecule, langerin
, CD207 antigen, langerin
, C-type lectin domain family 4 member K
, Langerhans cell specific c-type lectin
, C-type lectin domain family 4, member K
, CD 207 antigen