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CD69 encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Additionally we are shipping CD69 Antibodies (430) and CD69 Proteins (17) and many more products for this protein.
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Data show that a subset of inflammation-induced CD69(+) Kupffer cells which can feedback inhibit CD4 (show CD4 ELISA Kits) T cell response via cell surface TGF-beta1 (show TGFB1 ELISA Kits) at the late stage of immune response against infection.
Specific niches for lung-resident memory CD8 (show CD8A ELISA Kits)+ T cells at the site of tissue regeneration enable CD69-independent maintenance.
this study shows that CD69 serves as a key mediator of the pathogenesis of psoriasis by controlling LAT1-CD98 (show SLC7A5 ELISA Kits)-mediated metabolic cues
Loss of CD69 is associated with enhanced protection against vaccinia virus infection.
The data highlight the contribution of CD69 as a nonredundant key regulator of BIC/miR (show MLXIP ELISA Kits)-155-dependent regulatory T cell development and homeostasis.
Data show that after tumor necrosis factor alpha-induced protein 8 like-2 (TIPE2) gene was down-regulated, the expression of the CD69 antigen was increased, and the proliferation of T lymphocytes and the secretion of cytokines IL-2 and IFN-gamma were enhanced.
The generation of cancer-specific CD8 (show CD8A ELISA Kits)(+) CD69(+)-expressing lymphocytes that inhibit colon cancer growth has been described.
Maintenance of immune tolerance by Foxp3 (show FOXP3 ELISA Kits)+ regulatory T cells requires CD69 expression.
AIM(-/-) mice were highly susceptible to steatosis-associated HCC development, whereas no AIM(+/+) mouse developed the disease despite comparable liver inflammation and fibrosis in response to a long-term high-fat diet.
CD69 interference with S1P1 (show S1PR1 ELISA Kits) function regulates peripheral T cell retention.
this paper shows that decrease of CD69 levels on TCR Valpha7.2(+)CD4 (show CD4 ELISA Kits)(+) innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients
Higher CD69 expression were less sensitive to bendamustine and is associated with chronic lymphocytic leukemia.
In vitro functional assays showed that CD69(+) Treg cells exerted an important suppressive effect on the activation of T effector cells
results demonstrate the functional and mechanistic interplays between CD69 and S100A8 (show S100A8 ELISA Kits)/S100A9 (show S100A9 ELISA Kits) in supporting Treg-cell differentiation
Elevated expression of CD69 and CD161 on NK cells can be considered as immunological risk markers in RSA and IVF failure.
Human tumor-infiltrating CD4 (show CD4 ELISA Kits)+CD69+ T cells suppress T cell proliferation via membarene -bound TGF-beta1 (show TGFB1 ELISA Kits).
these findings identify CD69 and galectin-1 (show LGALS1 ELISA Kits) to be a novel regulatory receptor-ligand pair that modulates Th17 effector cell differentiation and function.
REVIEW: CD69 exerts a complex immunoregulatory role in humans, and that it could be considered as a target molecule for the therapy of immune-mediated diseases
Following coculture with GTKO/CD46 (show CD46 ELISA Kits) pig mesenchymal stromal cells, it is possible that upregulation of CD69 on human T cells initiates signaling events that would regulate CD4 (show CD4 ELISA Kits)+ and CD8 (show CD8A ELISA Kits)+ T cell activation and differentiation.
In patients with allergic rhinitis CD69 antigen is overexpressed on human peripheral blood natural killer cells reflecting their activation status.
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets.
, early activation antigen CD69
, Very Early Activation Antigen
, C-type lectin domain family 2, member C
, CD69 antigen (p60, early T-cell activation antigen)
, activation inducer molecule (AIM/CD69)
, early T-cell activation antigen p60
, early lymphocyte activation antigen
, leukocyte surface antigen Leu-23