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Plays a role in B-cell proliferation and differentiation.. Additionally we are shipping CD72 Proteins (20) and CD72 Kits (11) and many more products for this protein.
Showing 10 out of 163 products:
Human Monoclonal CD72 Primary Antibody for FACS, IP - ABIN192237
Mizrahi, Markel, Porgador, Bushkin, Mandelboim: CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72. in PLoS ONE 2007
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Human Monoclonal CD72 Primary Antibody for FACS, IP - ABIN94227
Kumanogoh, Shikina, Watanabe, Takegahara, Suzuki, Yamamoto, Takamatsu, Prasad, Mizui, Toyofuku, Tamura, Watanabe, Parnes, Kikutani: Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment. in International immunology 2005
Show all 4 Pubmed References
Human Monoclonal CD72 Primary Antibody for FACS, IHC (fro) - ABIN2472414
Katira, Kamal, Gordon: Occupancy of CD72 (the CD5 counterstructure) enhances interleukin-4-dependent CD23 expression in resting B lymphocytes. in Immunology 1992
Show all 2 Pubmed References
Human Monoclonal CD72 Primary Antibody for FACS - ABIN2689389
Pesando, Stucki: AFTR: a fifth human B-cell-specific surface antigen. in Human immunology 1990
CD72 appears to specifically inhibit B cell response to the endogenous TLR7 (show TLR7 Antibodies) ligand Sm/RNP (show RNPC3 Antibodies).
CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcepsilonRIalpha.
CD5 (show CD5 Antibodies) and CD72 play a critical role in maintaining regulatory T and B cell homeostasis
These results strongly suggest that the Cd72(c) is a crucial modifier gene that regulates Fas(lpr (show FAS Antibodies))-induced autoimmune disease due to its reduced activity of B cell signal regulation.
Cd72 polymorphism affects susceptibility to lupus phenotypes.
Inhibitory coreceptors CD72 and CD22 (show CD22 Antibodies) are responsible for setting the requirement of CD40 (show CD40 Antibodies) signaling for survival and proliferation of antigen-stimulated spleen B cells.
results strongly suggest that the apoptosis preventing signal evoked by CD72 ligation is delivered through the pathway of NF-kappaB (show NFKB1 Antibodies), c-Myc (show MYC Antibodies), p27(Kip1 (show CDKN1B Antibodies)) and cyclin (show PCNA Antibodies)
Strength of B-cell antigen receptor signals is strictly tuned by the interaction of CD100 (show SEMA4D Antibodies) with CD72; this interaction is essential for maintaining immunological homeostasis as well as generating a proper immune response.
CD72 plays a dominant role as a negative regulator of BCR (show BCR Antibodies) signaling in primary mature B lymphocytes.
CD72 is required to maintain B cell anergy and functions as a regulator of peripheral B cell tolerance
Interferon-alpha (show IFNA Antibodies)-induced CD100 (show SEMA4D Antibodies) expression on naive CD8 (show CD8A Antibodies)(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.
Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis
CD72 expression on activated B cells of SLE patients was significantly lower than that of normal controls. sema3A (show SEMA3A Antibodies) enhanced CD72 expression of B cells, but it was still lower in SLE patients than in normal individuals.
data demonstrated aberrant expression of CD72 exists on B cells of myasthenia gravis and multiple sclerosis patients and expression level of CD72 molecule has a significantly negative correlation with anti-AchR antibody levels in myasthenia gravis
CD72 mRNA expression level correlates with Sema4D (show SEMA4D Antibodies) expression in peripheral blood mononuclear cells in immune thrombocytopenia.
CD100 (show SEMA4D Antibodies), CD72 and CD45 (show PTPRC Antibodies) were expressed in placenta and exhibited different mRNA and protein levels in normal pregnancy and miscarriage. Protein levels were highly dysregulated around 10 weeks of gestation in first and second miscarriage placentas.
CD100 (show SEMA4D Antibodies)-CD72 interaction can be the mechanism by which NK cell communicate with B cells.
Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine (show CCL1 Antibodies) production.
results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B-232Thr, possibly by increasing the AS isoform of CD72
CD72 is a key molecule in regulating mature B cell differentiation; CD72 signaling reduces the expression of X-box binding protein 1 (show XBP1 Antibodies) in B cells
Plays a role in B-cell proliferation and differentiation.
B-cell differentiation antigen CD72
, lymphocyte antigen 32
, CD72 antigen