CD79a Molecule, Immunoglobulin-Associated alpha Proteins (CD79A)

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Additionally we are shipping CD79a Molecule, Immunoglobulin-Associated alpha Antibodies (742) and CD79a Molecule, Immunoglobulin-Associated alpha Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD79A 12518 P11911
CD79A 973 P11912
Rat CD79A CD79A 681236  
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Top CD79a Molecule, Immunoglobulin-Associated alpha Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
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Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$707.00
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Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$768.00
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HEK-293 Cells Human DYKDDDDK-His Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
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Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 13 to 16 Days
$400.00
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Human Cells Mouse Fc Tag,ECD 100 μg Log in to see 14 to 16 Days
$437.80
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$325.44
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HEK-293 Cells Human His-DYKDDDDK-Strep II Tag 25 μg Log in to see 11 to 12 Days
$792.50
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,203.67
Details

CD79A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
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Human , , , , ,
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More Proteins for CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) Interaction Partners

Mouse (Murine) CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) interaction partners

  1. BCR activation is accompanied by asymmetric conformational changes, possibly promoting the binding of Igalpha and Igbeta to differently localized signaling complexes

  2. CD79a myeloid cells showed enhanced ability to promote primary tumor growth and metastasis.

  3. Data indicate that in the absence of DGKzeta, the threshold for B cell antigen receptor (BCR) signaling, measured as activation of the Ras-extracellular signal-regulated kinase (ERK) pathway, was markedly reduced in mature follicular B cells.

  4. Data show that the B cell antigen receptor (BCR) and Igalpha may be required for B cell survival because they function as adaptor proteins in a BAFFR signaling pathway leading to activation of Syk, indicating crosstalk between the two receptors.

  5. The mouse B cell-specific mb-1 gene encodes an immunoreceptor tyrosine-based activation motif (ITAM) protein that may be evolutionarily conserved in diverse species by purifying selection.

  6. endocytosed BCR sequentially regulates MAPK and Akt signaling pathways from intracellular compartments

  7. Data indicate that both the Igalpha and the Igbeta cytoplasmic domains alone are sufficient for trafficking to lysosomal compartments, and are unaffected by mutation of 4 amino acid residues within their respective ITAMs.

  8. Arginine 198 in the tail of the Igalpha subunit of the BCR is methylated by the protein arginine methyltransferase 1. Methylation negatively regulates the calcium and PI-3 kinase pathways of the BCR, promoting signals leading to B cell differentiation.

  9. The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

  10. IgA deficiency in lymphotoxin-deficient (LT(-/-)) mice could be fully reversed by reconstitution with LT-expressing bone marrow, despite the absence of both LNs and PPs.

  11. The VHDJH recombination process at the IgH locus and the survival of pro-B cells that carry these rearrangements do not depend on the expression of Ig-alpha molecules.

  12. Selective adherence of IgA to murine Peyer's patch M cells: evidence for a novel IgA receptor.

  13. Data show that expression of endogenous mb-1 transcripts correlates most closely with early-B-cell factor (EBF) expression and negatively with Id1, an inhibitor of E2A protein function, linking regulation of the mb-1 gene with EBF and E2A.

  14. Retrovirally expressed human Pax-5 protein activates endogenous early B-cell-specific mb-1 genes in mouse plasmacytoma cells, but only when the promoter is hypomethylated.

  15. Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription.

  16. Ig-alpha immunoreceptor tyrosine-based activation motif (ITAM) tyrosines (Y182 and Y193) are necessary for efficient pre-B cell differentiation.

  17. gamma1 chain can exert a unique signaling function that can partially replace that of the Ig alpha/beta heterodimer in B cell maintenance and may contribute to memory B cell physiology

  18. MHC II structural requirements for mediation of cell death signaling in a murine B cell lymphoma with Igalpha/beta

Human CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) interaction partners

  1. The incidence of MYD88 and CD79B mutations in patients with CD5(+) DLBCL is lower than that in patients with DLBCL-SS, suggesting that CD5(+) DLBCL is not the same disease as DLBCL-SS in terms of gene mutation status.

  2. Data show that Bruton tyrosine kinase (BTK)inhibitor Ibrutinib augments MALT lymphoma associated translocation protein (MALT1) inhibition by S-Mepazine in CD79 antigen mutant activated B cell-subtype (ABC) of diffuse large B cell lymphoma (DLBCL).

  3. Phosphorylation of CD79a causes a decrease in helical propensity in the C-terminal region, for CD79b, the opposite was observed and phosphorylation resulted in an increase of helical propensity in the C-terminal part.

  4. High intensity of caries is associated with increased levels of some salivary components - sIgA, histatin-5 and lactoperoxidase.

  5. CD79a plays a functional role in the tumor promoting effects of myeloid cells, and may represent a novel target for cancer therapy.

  6. STN produced significant antitumor effects in a mouse xenograft model of CD79A/B-mutated DLBCL.

  7. CD79a may be helpful marker in the differential diagnosis of classical Hodgkin's lymphoma and primary mediastinal B-cell lymphoma

  8. Unlike the B29 octamer motif, the mb-1 octamer motif does not have the essential sequence required for OBF-1/Bob1 interaction, therefore its promoter is not transactivated by OBF-1/Bob1.

  9. B cell-restricted mb-1 gene: expression, function, and lineage infidelity. Review.

  10. There is a somatic hypermutation of this gene in B-cell lymphoma and multiple myeloma.

  11. Results indicate that PAX5 is a more specific marker than CD79a for B-cell ALL diagnosis.

  12. lower levels of B-cell receptor surface expression observed in chronic lymphocytic leukemia are accounted for by an impaired glycosylation and folding of the mu and CD79a chains.

  13. FISH findings indicate that CD79a, despite its specificity for B-cell differentiation, represented the aberrant presence of a B-cell antigen in leukemias of distinct myeloid linage.

  14. Acute leukemia with t(8;21) coexpresses CytCD79a represent biphenotypic acute leukemia.

  15. Anti-CD79b antibodies downregulated surface B-cell receptor and were trafficked to the lysosomal-like major histocompatibility complex class II-positive compartment of a mouse xenograft model of non-Hodgkin lymphoma.

  16. Ig-alpha was phosphorylated in all myeloma IgG BCR isolates, the 31-kD variant being phosphorylated most frequently. It was not phosphorylated in normal control B cells.

  17. Median survival time of cytoplasmic CD79 alpha positive group was shorter than that of cytCD79a negative group in acute myeloid leukemia.

  18. we determined the significance of loss or downregulation of CD79a, overexpression of cyclinD1, and c-maf expression in bone marrow specimens with plasma cell myeloma

CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) Protein Profile

Protein Summary

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with CD79A

  • CD79a molecule (CD79A)
  • CD79A antigen (immunoglobulin-associated alpha) (Cd79a)
  • CD79a molecule (Cd79a)
  • Cd79a molecule-like (Cd79al)
  • CD79A protein
  • IG-alpha protein
  • IGA protein
  • Igalpha protein
  • Ly-54 protein
  • Ly54 protein
  • MB-1 protein

Protein level used designations for CD79A

CD79a molecule, immunoglobulin-associated alpha , B-cell antigen receptor complex-associated protein alpha chain , Ig alpha , MB-1 membrane glycoprotein , immunoglobulin-associated alpha , membrane-bound immunoglobulin-associated protein , surface IgM-associated protein , CD79a antigen (immunoglobulin-associated alpha) , ig-alpha , CD79-alpha protein , CD79A antigen (immunoglobulin-associated alpha) , B-cell antigen receptor complex-associated protein alpha-chain

GENE ID SPECIES
740560 Pan troglodytes
12518 Mus musculus
973 Homo sapiens
100052219 Equus caballus
100190992 Sus scrofa
281674 Bos taurus
100724815 Cavia porcellus
484483 Canis lupus familiaris
681236 Rattus norvegicus
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