CD79a Protein (AA 33-143) (His tag)
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- Target See all CD79a (CD79A) Proteins
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-143
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD79a protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- LWMHKVPASL MVSLGEDAHF QCPHNSSNNA NVTWWRVLHG NYTWPPEFLG PGEDPNGTLI IQNVNKSHGG IYVCRVQEGN ESYQQSCGTY LRVRQPPPRP FLDMGEGTKN RLEHHHHHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product CD79A Protein
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B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-143) protein (His-DYKDDDDK-Strep II Tag)
CD79A Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-140) protein (GST tag)CD79A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
B-cell antigen receptor complex-associated protein alpha chain (CD79A) protein (His tag)CD79A Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
B-cell antigen receptor complex-associated protein alpha chain (CD79A) protein (Fc Tag,ECD)CD79A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Alternative Name
- CD79A (CD79A Products)
- Synonyms
- CD79A Protein, Ig-alpha Protein, Iga Protein, Igalpha Protein, Ly-54 Protein, Ly54 Protein, mb-1 Protein, IGA Protein, MB-1 Protein, IG-alpha Protein, CD79a molecule Protein, CD79A antigen (immunoglobulin-associated alpha) Protein, Cd79a molecule-like Protein, CD79A Protein, Cd79a Protein, Cd79al Protein
- Background
- CD79A, also known as B-cell antigen receptor complex-associated protein alpha chain isoform 1, is a membrane-spanning, signal-transducing components of the B-cell receptor. It plays multiple and diverse roles in B cell development and function. It can be a cause of agammaglobulinemia. It is upregulated on MDSCs and activated in response to soluble factors secreted by tumor cells. It plays a functional role in the tumor promoting effects of myeloid cells, and may represent a novel target for cancer therapy. Recombinant human CD79A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 13.6kDa (119aa) 18-28kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_001774
- UniProt
- P11912
- Pathways
- BCR Signaling
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