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CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. Additionally we are shipping CDC42 Effector Protein (Rho GTPase Binding) 1 Proteins (6) and many more products for this protein.
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Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling.
CDC42EP1 activation is required for mannose receptor-mediated phagocytosis by alveolar macrophages.
Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells.
report that differentiation of embryonic stem cells toward trophectoderm is accompanied by enhanced actin protrusion and cell motility that require upregulation of Borg5.
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow.
55 kDa bone marrow stromal/endothelial cell protein
, binder of Rho GTPases 5
, cdc42 effector protein 1
, serum constituent protein
, serum protein MSE55
, binder of Rho GTPase 5