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CDC42EP3 encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Additionally we are shipping CDC42EP3 Proteins (5) and many more products for this protein.
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Human Polyclonal CDC42EP3 Primary Antibody for ELISA, WB - ABIN564625
Schnack, Danzer, Hengerer, Gillardon: Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with Cdc42 effector proteins. in Neuroscience 2008
Results provide evidence that Cdc42EP3 function in cancer-associated fibroblasts relies on tight regulation by Cdc42.
Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling.
The expression of CDC42EP3 mRNA was significantly increased by 19.7% in dorsal prefrontal cortex in patient with schizophrenia.
This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.
CDC42 effector protein (Rho GTPase binding) 3
, cdc42 effector protein (Rho GTPase binding) 3
, cdc42 effector protein 3
, Cdc42 effector protein 3
, CRIB-containing BORG2 protein
, MSE55-related Cdc42-binding protein
, MSE55-related protein
, binder of Rho GTPases 2