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Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways (By similarity).. Additionally we are shipping CDKN2A Interacting Protein Proteins (7) and CDKN2A Interacting Protein Kits (3) and many more products for this protein.
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CARF promotes carcinogenesis in p53 (show TP53 Antibodies)-deficient cells by repressing p21WAF1 and promoting cell cycle progression.
The results suggest that CARF regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 (show XRN2 Antibodies) between the nucleoplasm and nucleolus.
CARF regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling.
Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66 (show WDR66 Antibodies), USP20 (show USP20 Antibodies) and OR7C2 (show OR7C2 Antibodies) in a Korean population.
CARF knockdown elicited DNA damage response as evidenced by increased levels of phosphorylated ATM (show ATM Antibodies) and gammaH2AX (show H2AFX Antibodies), leading to induction of mitotic arrest and eventual apoptosis.
CARF may act as a novel key regulator of the p53 (show TP53 Antibodies) pathway at multiple checkpoints
cooperates with human p14ARF (show CDKN2A Antibodies) in activating p53 (show TP53 Antibodies)
CARF may exert a vital control on p53 (show TP53 Antibodies)-HDM2-p21(WAF1 (show CDKN1A Antibodies)) pathway that is central to the cell cycle control, senescence, and DNA damage response of human cells
CARF exerts a vital control on the p53 (show TP53 Antibodies)-HDM2-p21WAF1 pathway that is frequently altered in cancer cells.
CARF plays a dual role in regulating p53 (show TP53 Antibodies)-mediated senescence and apoptosis, the two major tumor suppressor mechanisms.
Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways (By similarity).
, collaborates/cooperates with ARF (alternate reading frame) protein
, collaborator of ARF
, CDKN2A interacting protein
, protein CDKN2AIP homolog A