anti-CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) Antibodies

CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008].. Additionally we are shipping CNDP2 Proteins (15) and CNDP2 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CNDP2 291394 Q6Q0N1
CNDP2 66054 Q9D1A2
CNDP2 55748 Q96KP4
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Top anti-CNDP2 Antibodies at antibodies-online.com

Showing 10 out of 109 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CNDP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-CNDP2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Jurkat cell lysate 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CNDP2 Antibody Titration: 0.2-1 ug/mlPositive Control: COLO205 cell lysate WB Suggested Anti-CNDP2  Antibody Titration: 0.2-1 µg/mL  Positive Control: COLO205 cell lysate  CNDP2 is supported by BioGPS gene expression data to be expressed in COLO205 100 μL 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of CNDP2 using K562 whole cell lysates 100 μL 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC200120 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-CNDP2 antibody (ABIN2454773), and then analyzed by flow cytometry. Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-CNDP2 mouse monoclonal antibody. (ABIN2454773) 0.1 mL 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), WB Human, Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μL 11 to 14 Days
$484.00
Details
Mouse Rabbit Un-conjugated ELISA, WB 100 μL 14 to 16 Days
$312.53
Details
Mouse Rabbit Un-conjugated IHC (p) Immunochemical staining of mouse CNDP2 in mouse kidney with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to nephric tubule. 100 μL 14 to 16 Days
$312.53
Details

Top referenced anti-CNDP2 Antibodies

  1. Human Monoclonal CNDP2 Primary Antibody for ELISA, WB - ABIN527646 : Licker, Côte, Lobrinus, Rodrigo, Kövari, Hochstrasser, Turck, Sanchez, Burkhard: Proteomic profiling of the substantia nigra demonstrates CNDP2 overexpression in Parkinson's disease. in Journal of proteomics 2012 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CNDP2 Interaction Partners

Mouse (Murine) CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) interaction partners

  1. this study shows that PEP-1-PEA15 suppresses inflammatory responses by regulation of MAPK in macrophages and animal models

  2. These results provide evidence showing that intradimer interaction of H228 with the reaction center of the dimer counterpart is essential to the enzymatic activity of Cn2.

  3. These findings suggest that the transduced PEP-1-PRX2 has neuroprotective functions against oxidative stress-induced cell death in vitro and in vivo

  4. Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2.

Human CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) interaction partners

  1. 2 SNPs (rs7244647 in CNDP1 and rs4891558 in CNDP2) were associated with obesity risk. In addition, these associations were observed only in the group with high carbohydrate and low carotene intake but not in the group with low carbohydrate and high carotene intake.

  2. The CNDP2 rs6566810 (A/A genotype) is overrepresented in endurance athletes, but only in international-level endurance athletes. Three SNPs (CNDP2 rs3764509, CNDP2-CNDP1 rs2346061, and CNDP1 rs2887) were overrepresented in power athletes compared with nonathletes.

  3. These results suggest that the zinc form of CN2 is an active enzyme, but with a different substrate specificity from that of the manganese form.

  4. To identify substrates of orphan transporter ATP-binding cassette subfamily C member 5 (ABCC5), identified a class of metabolites, N-lactoyl-amino acids, and found that a protease, cytosolic nonspecific dipeptidase 2 (CNDP2), catalyzes their formation.

  5. Expression of CN2 in clinical colon tumors and colon cancer cell lines was significantly higher than that in normal colon mucosa cell lines. Knockdown of CNDP2 can inhibit the proliferation of colon cancer in vitro and retarded carcinogenesis in vivo.

  6. Results suggest that CNDP2 acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway.

  7. a key role of CNDP2 in PD neurodegeneration, by mechanisms that could involve oxidative stress, protein aggregation or inflammation.

  8. deletion of the CPGL gene is a poor prognostic marker in resected pancreatic cancer, and functional studies suggest the CPGL gene as growth suppressor gene in pancreatic cancer.

  9. Common variants in CNDP1 and CNDP2 play a role in susceptibility to kidney disease in patients with type 2 diabetes.

  10. the crystal structure of the flop-selective allosteric modulator, PEPA, bound to the binding domains of the GluA2 and GluA3 flop isoforms of AMPA receptors

  11. Our large, comprehensive study did not find an association between the D18S880 microsatellite or any other polymorphisms in the CNDP2-CNDP1 genomic region and susceptibility for diabetic nephropathy in type 1 diabetes

Maize/Corn (Zea mays) CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) interaction partners

  1. Transgenic rice plants over-expressing the maize C4-pepc gene encoding phosphoenolpyruvate carboxylase (PC) and wild-type (WT) rice plants were subjected to PEG 6000 treatments to simulate drought stress. Compared with WT, PC had the higher survival rate and net photosynthetic rate after 16days of drought treatment, and had higher relative water content in leaves after 2h of drought treatment as well.

  2. PEPC can improve both stress tolerance and grain yield in wheat.

  3. ZmPEPC gene can enhance photochemical and antioxidant enzyme activity, upregulate the expression of photosynthesis-related genes, delay degradation of chlorophyll, change contents of proline and other metabolites in wheat, and ultimately improves its heat tolerance.

CNDP2 Antigen Profile

Protein Summary

CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003

Gene names and symbols associated with CNDP2

  • carnosine dipeptidase 2 (Cndp2) antibody
  • CNDP dipeptidase 2 (metallopeptidase M20 family) (Cndp2) antibody
  • CNDP dipeptidase 2 (metallopeptidase M20 family) (CNDP2) antibody
  • carnosine dipeptidase 2 (CNDP2) antibody
  • CNDP dipeptidase 2 (metallopeptidase M20 family) (cndp2) antibody
  • carnosine dipeptidase 2 (cndp2) antibody
  • CNDP dipeptidase 2 (metallopeptidase M20 family) S homeolog (cndp2.S) antibody
  • CNDP dipeptidase 2 (metallopeptidase M20 family) L homeolog (cndp2.L) antibody
  • phosphoenolpyruvate carboxylase 1 (pep1) antibody
  • 0610010E05Rik antibody
  • C76600 antibody
  • cn2 antibody
  • CNDP2 antibody
  • cndp2b antibody
  • cpgl antibody
  • darmin-r antibody
  • Dip-2 antibody
  • HsT2298 antibody
  • Pep-1 antibody
  • Pep1 antibody
  • PEPA antibody
  • pepc antibody
  • PEPC1 antibody
  • PEPCase antibody
  • PPC1 antibody
  • PPEPC4 antibody
  • wu:fd20d11 antibody
  • wu:fe17f09 antibody
  • zgc:92569 antibody

Protein level used designations for CNDP2

cytosolic non-specific dipeptidase , cytosolic nonspecific dipeptidase 2 , cytosolic nonspecific dipeptidase , glutamate carboxypeptidase-like protein 1 , peptidase 1 , peptidase A , CNDP dipeptidase 2 , CNDP dipeptidase 2 (metallopeptidase M20 family) , CNDP dipeptidase 2 b , CNDP dipeptidase 2 (metallopeptidase M20 family) b , CNDP dipeptidase 2 a , P-pyruvate carboxylase , PEP carboxylase , PEPCase 1 , phosphoenolpyruvate carboxylase 1

GENE ID SPECIES
291394 Rattus norvegicus
66054 Mus musculus
421013 Gallus gallus
55748 Homo sapiens
695080 Macaca mulatta
394907 Xenopus (Silurana) tropicalis
476166 Canis lupus familiaris
100174694 Pongo abelii
512626 Bos taurus
327288 Danio rerio
380001 Xenopus laevis
446978 Xenopus laevis
100061697 Equus caballus
100347984 Oryctolagus cuniculus
542372 Zea mays
100735444 Cavia porcellus
100158127 Sus scrofa
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