anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) Antibodies

CACNA2D3 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Additionally we are shipping CACNA2D3 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CACNA2D3 55799 Q8IZS8
CACNA2D3 12294 Q9Z1L5
CACNA2D3 306243 Q8CFG5
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Top anti-CACNA2D3 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, WB   0.4 mL Log in to see 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CACNA2D3 Antibody (C-term) (ABIN653695) in HepG2 cell line lysates (35 µg/lane). CACNA2D3 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using CACNA2D3 antibody. Western blot analysis of extracts of various cell lines, using CACNA2D3 antibody (ABIN4903101) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. 100 μL Log in to see 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated IHC, WB   500 μg Log in to see 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated FACS, ELISA, WB   200 μL Log in to see 11 to 16 Days
$658.43
Details
Human Rabbit PE FACS, ELISA, WB   200 μL Log in to see 11 to 14 Days
$1,101.83
Details
Human Rabbit HRP FACS, ELISA, WB   200 μL Log in to see 11 to 14 Days
$1,101.83
Details
Human Rabbit FITC FACS, ELISA, WB   200 μL Log in to see 11 to 14 Days
$1,101.83
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, ELISA, WB   200 μL Log in to see 11 to 14 Days
$1,101.83
Details
Human Rabbit APC FACS, ELISA, WB   200 μL Log in to see 11 to 14 Days
$1,101.83
Details

Top referenced anti-CACNA2D3 Antibodies

  1. Human Polyclonal CACNA2D3 Primary Antibody for IHC (fro), IHC (p) - ABIN447505 : Bellessort, Bachelot, Grouthier, De Lombares, Narboux-Neme, Garagnani, Pirazzini, Astigiano, Mastracci, Fontaine, Alfama, Duvernois-Berthet, Levi: Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain. in Journal of pain research 2018 (PubMed)

More Antibodies against CACNA2D3 Interaction Partners

Human Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) interaction partners

  1. Nine of the 32 (28.1%) iCCA patients had gene mutations at chromosome 3p, totaling 11 mutations across five genes. Those included five (15.6%) BAP1 mutations, two each (6.3%) of CACNA2D3 and RASSF1 mutations, and one each (3.1%) of ATG7 and PLCD1 mutations. Six (18.8%) cases had concurrent loss of chromosome 3p and gene mutations.

  2. Findings demonstrate the tumor suppressive role of CACNA2D3 in gliomas. CACNA2D3 operates via Ca 2thorn signaling and the activation of non-canonical Wnt signaling to inhibit cell proliferation and motility and induce apoptosis.

  3. The risk of developing anaemia is increased in reproductive age women carriers of A allele of rs1868505 (CACNA2D3) and/or T allele of rs13194491 (HIST1H2BJ).

  4. CACNA2D3-mediated increase in intracellular calcium (Ca2+) can induce mitochondrial-mediated apoptosis.

  5. CACNA2D3 is a novel tumor suppressor gene responsible for the 3p21 deletion event that plays a critical suppressing role in the development and progression of esophageal squamous cell carcinoma.

  6. CACNA2D3 polymorphism rs1375515 plays important role in iron status and is associated with the levels of iron-related biomarkers, as well as with iron clinical phenotypes (normal, iron de fi cient and anaemic).

  7. Expression of CACNA2D3 mRNA is regulated in breast cancer cell lines by methylation in the CpG island located in the 5' regulatory region of the gene.

  8. High CACNA2D3 gene expression is assiciated with glioblastoma multiforme.

  9. In humans, study found single-nucleotide polymorphisms in alpha2delta3 that are associated with reduced acute heat pain sensitivity in healthy volunteers and chronic postsurgical back pain.

  10. did not detect submicroscopic deletion or duplication nor sequence alteration in either CACNA2D3 or WNT5A in ZLS-affected individuals

  11. Loss of CACNA2D3 expression through aberrant promoter hypermethylation may contribute to gastric carcinogenesis.

  12. This publication primarily discusses the alpha2/delta 4 subunit, but also contains cDNA data relating to the gene described in this record.

Mouse (Murine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) interaction partners

  1. The data of this study demonstrate that knock out of CACN alpha2delta3 results in some structural abnormalities whose functional implications converge to dedifferentiation of sensory activation.

  2. our results identify a novel role for the alpha2delta3 auxiliary subunit in the structure and function of specific synapses in the mammalian auditory pathway and in auditory processing disorders.

  3. Mice mutant for the stj ortholog CACNA2D3 (alpha2delta3) exhibit impaired behavioral heat pain sensitivity.

CACNA2D3 Antigen Profile

Protein Summary

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene names and symbols associated with CACNA2D3

  • calcium voltage-gated channel auxiliary subunit alpha2delta 3 (CACNA2D3) antibody
  • calcium channel, voltage dependent, alpha2/delta subunit 3 (cacna2d3) antibody
  • calcium channel, voltage-dependent, alpha2/delta subunit 3 (Cacna2d3) antibody
  • calcium voltage-gated channel auxiliary subunit alpha2delta 3 (Cacna2d3) antibody
  • Cacnad3 antibody
  • HSA272268 antibody

Protein level used designations for CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta 3 subunit , voltage-dependent calcium channel subunit alpha-2/delta-3 , calcium channel, voltage-dependent, alpha 2/delta subunit 3 , calcium channel, voltage-dependent, alpha 2/delta 3 subunit-like , voltage-dependent calcium channel subunit alpha-2/delta-3-like , calcium channel alpha2-delta3 subunit , voltage-gated calcium channel subunit alpha-2/delta-3 , alpha 2 delta-3 , alpha2delta3 , calcium channel, voltage dependent, alpha2/delta subunit 3

GENE ID SPECIES
415996 Gallus gallus
460457 Pan troglodytes
476585 Canis lupus familiaris
519644 Bos taurus
100148645 Danio rerio
100400467 Callithrix jacchus
100448999 Pongo abelii
55799 Homo sapiens
12294 Mus musculus
306243 Rattus norvegicus
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