anti-Calcium and Integrin-Binding Protein 1 (CIB1) Antibodies

CIB1 encodes a member of the EF-hand domain-containing calcium-binding superfamily. Additionally we are shipping CIB1 Proteins (10) and CIB1 Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CIB1 10519 Q99828
CIB1 23991 Q9Z0F4
CIB1 81823 Q9R010
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Top anti-CIB1 Antibodies at antibodies-online.com

Showing 10 out of 116 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  Cib1  Sample Type:  Rat Muscle lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CIB1 expression in HEK293T (A), H9C2 (B), rat brain (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB Anti- CIB1 Picoband antibody, Western blotting All lanes: Anti CIB1  at 0.5ug/ml Lane 1: Rat Spleen Tissue Lysate at 50ug Lane 2: Rat Brain Tissue Lysate at 50ug Lane 3: Rat Thymus Tissue Lysate at 50ug Lane 4: Human Placenta Tissue Lysate at 50ug Lane 5: MCF-7 Whole Cell Lysate at 40ug Lane 6: NIH3T3 Whole Cell Lysate at 40ug Predicted bind size: 27KD Observed bind size: 27KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IHC, WB Immunoperoxidase of monoclonal antibody to CIB1 on formalin-fixed paraffin-embedded human colon (antibody concentration 3 µg/mL). Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (46.75 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot: CIB1 Antibody (1D1) [NBP1-04279] - Cell lysates of HT29 (40ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CIB1 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Log in to see 12 to 15 Days
$418.10
Details
Human Mouse Un-conjugated ELISA, IHC, WB Figure 1: Western blot analysis using CIB1 mouse mAb against truncated CIB1 recombinant protein (1) and A431 cell lysate (2). Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded human thalamus (left) and glioma (right) tissue, showing membrane localization using CIB1 mouse mAb with DAB staining. Dilution: 1/200 - 1/1000 100 μL Log in to see 10 to 11 Days
$491.79
Details
Human Rabbit Un-conjugated WB CIB1 Antibody (C-term) (ABIN1881205) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the CIB1 antibody detected the CIB1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image CIB1 antibody detects CIB1 protein at cytoplasm on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded lung carcinoma. CIB1 antibody , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: A431 , 12% SDS PAGE CIB1 antibody antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using CIB1 antibody. Immunohistochemistry of paraffin-embedded human prostate using CIB1 antibody (ABIN1871861) at dilution of 1:100 (40x lens). 100 μL Log in to see 11 to 13 Days
$366.77
Details

Top referenced anti-CIB1 Antibodies

  1. Human Polyclonal CIB1 Primary Antibody for WB - ABIN1881205 : Jarman, Moretti, Zebol, Pitson: Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1. in The Journal of biological chemistry 2009 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal CIB1 Primary Antibody for IHC, ELISA - ABIN969057 : Gentry, Singer, Betts, Yang, Ferrara, Sondek, Parise: Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal CIB1 Primary Antibody for ELISA, WB - ABIN532973 : Yuan, Leisner, McFadden, Wang, Larson, Clark, Boudignon-Proudhon, Lam, Parise: CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation. in The Journal of cell biology 2006 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal CIB1 Primary Antibody for IHC, ELISA - ABIN965898 : White, Yang, Monteiro, Foskett: CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CIB1 Interaction Partners

Human Calcium and Integrin-Binding Protein 1 (CIB1) interaction partners

  1. CIB1 may regulate tumor biological processes that range from adhesion, migration, cell survival, proliferation, and angiogenesis [review]

  2. In patients with chronic stable ischemic heart failure, the diagnostic value of urine CIB1 outperforms that of serum pro-BNP

  3. this study identifies CIB1 and CIB2 as host helper factors for HIV-1 replication that are required for optimal receptor-mediated viral entry

  4. In summary, as a multifunctional protein, CIB1 serving not only as a Ca2+ modulating protein, most surprisingly, but also as an important potential tumor promoting factor. [review]

  5. Results suggest that interaction of CIB1 with alphaIIb is one of the early events occurring during outside-in signaling. Furthermore, CIB1 recruits FAK to the alphaIIbbeta3 complex at the filopodia where FAK is activated, which in turn activates c-Src, resulting in propagation of outside-in signaling leading to platelet spreading.

  6. we found that ectopic expression of oncogenic KRas and HRas in cells resulted in elevated CIB1 expression. We previously described the Ca(2+)-myristoyl switch function of CIB1, and its ability to facilitate agonist-induced plasma membrane localisation of sphingosine kinase 1 (SK1), a location where SK1 is known to elicit oncogenic signalling.

  7. a large subset of TNBCs depend on CIB1 for cell survival and tumor growth, independent of CIB1 expression levels.

  8. mRNA and protein expression levels of CIB1 were decreased in the oligoasthenozoospermia patients.CIB1 may be involved in the pathogenesis of oligoasthenozoospermia by the CDK1 signaling pathway.

  9. High serum CIB1 levels are associated with pancreatic cancer.s

  10. KIP binding to TRF2 enhances the telomere-binding activity of TRF2, suggesting that KIP acts as a positive regulator of TRF2 function.

  11. these studies suggested that Kaposi's sarcoma-associated herpesvirus utilizes CIB1 as one of the key molecule(s) to coordinate and sustain the EphA2 mediated signaling involved in its entry

  12. CIB1a is a novel mediator of PKD2-driven carcinogenesis.

  13. we present data that show that CIB1 binds to seven additional alpha-integrin CT peptides, bringing the total number of alpha-integrins that can associate with CIB1 to eight.

  14. Results indicate that CIB1 is uniquely positioned to regulate PI3K/AKT and MEK/ERK signaling and that simultaneous disruption of these pathways synergistically induces a nuclear GAPDH-dependent cell death.

  15. The CIB1 and calcineurin expression was increased in AF atrial tissue and was related to the type of AF. This finding suggests that CIB1 may be involved in the pathogenesis of AF in VHD patients.

  16. results suggest that CIB1 positively regulates cell migration and is necessary for the recruitment of FAK to the focal adhesions. Furthermore, CIB1-induced cell migration is dependent on MAP kinase signaling and its function is attenuated by PAK1

  17. CIB1 may be used as a novel prognostic factor and possibly an attractive therapeutic target for hepatocellular carcinoma.

  18. CaMy1 via SCG10 couples Ca(2+) signals with the dynamics of microtubules during neuronal outgrowth in the developing brain.

  19. analysis of Ca2+-CIB1 and Mg2+-CIB1 and their interactions with the platelet integrin alphaIIb cytoplasmic domain

  20. Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression.

Mouse (Murine) Calcium and Integrin-Binding Protein 1 (CIB1) interaction partners

  1. mouse erythrocyte calmyrin is an interacting molecule of the rodent malaria parasite Plasmodium yoelii RhopH complex.

  2. results suggest that interaction of CIB1 with alphaIIb is one of the early events occurring during outside-in signaling. Furthermore, CIB1 recruits FAK to the alphaIIbbeta3 complex at the filopodia where FAK is activated, which in turn activates c-Src, resulting in propagation of outside-in signaling leading to platelet spreading.

  3. CIB1 is involved in regulating endomitosis, perhaps through its interaction with Polo-like kinase 3

  4. Data demonstrate that CIB1 is not required for AID to mediate antibody gene diversification processes. It remains possible that CIB1 has an alternative, a redundant or a subtle non-limiting regulatory role in AID biology.

  5. CIB1 functions as a previously undescribed regulator of cardiac hypertrophy through its ability to regulate the association of calcineurin with the sarcolemma and its activation.

  6. CIB1 is a key regulator of thrombosis, by affecting platelet spreading, but not platelet filopodia formation.

  7. CIB co-immunoprecipitated with Snk and inhibited the kinase activity of Snk, suggesting that CIB is a negative regulator for Snk kinase activity.

  8. MEFs derived from Cib1(-/-) mice exhibit a much slower growth rate compared to Cib1(+/+) MEFs, suggesting that CIB1 regulates the cell cycle, differentiation of spermatogenic germ cells, and/or differentiation of supporting Sertoli cells.

  9. loss of CIB1 in endothelial cells decreases p21-activated kinase 1 activation, downstream extracellular signal-regulated kinase 1/2 activation, and matrix metalloproteinase 2 expression, all of which are known to contribute to angiogenesis.

CIB1 Antigen Profile

Protein Summary

This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CIB1

  • calcium and integrin binding 1 (calmyrin) (cib1) antibody
  • calcium and integrin-binding protein 1 (CpipJ_CPIJ003501) antibody
  • calcium and integrin binding 1 (CIB1) antibody
  • calcium and integrin binding 1 (cib1) antibody
  • Calcium and integrin-binding protein 1 (kip1) antibody
  • calcium and integrin binding 1 (calmyrin) (Cib1) antibody
  • calcium and integrin binding 1 (Cib1) antibody
  • Cib antibody
  • Cibkip antibody
  • CIBP antibody
  • Kip antibody
  • KIP1 antibody
  • Prkdcip antibody
  • Sip2-28 antibody
  • zgc:112015 antibody

Protein level used designations for CIB1

calcium and integrin-binding protein 1 , calcium and integrin binding protein 1 , Calcium and integrin-binding protein 1 , DNA-PK interaction protein , DNA-PKcs-interacting protein , DNA-dependent protein kinase interacting protein , SNK-interacting protein 2-28 , CIB , calcium and integrin binding, protein kinase interacting protein , calmyrin , kinase-interacting protein , protein kinase, DNA activated, catalytic polypeptide interacting protein , KIP , calcium- and integrin-binding protein

GENE ID SPECIES
550376 Danio rerio
6034872 Culex quinquefasciatus
100141300 Ovis aries
100286603 Salmo salar
100301714 Oncorhynchus mykiss
10519 Homo sapiens
23991 Mus musculus
81823 Rattus norvegicus
479044 Canis lupus familiaris
100157484 Sus scrofa
510141 Bos taurus
100726412 Cavia porcellus
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