Calpastatin (CAST) ELISA Kits

The protein encoded by CAST is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. Additionally we are shipping Calpastatin Antibodies (89) and Calpastatin Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CAST 831 P20810
CAST 12380  
CAST 25403 P27321
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Top Calpastatin ELISA Kits at

Showing 7 out of 22 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.39 ng/mL 1.56-100 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
Cow 7.81 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Mouse 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
  96 Tests Log in to see 2 to 3 Days
Mouse < 0.054 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
  96 Tests Log in to see 11 to 18 Days
Sheep 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days

More ELISA Kits for Calpastatin Interaction Partners

Human Calpastatin (CAST) interaction partners

  1. single nucleotide polymorphisms in CAST gene confer risk for keratoconus susceptibility in Han Chinese population

  2. Kaposi sarcoma-associated herpesvirus reduces CAST (calpastatin) and consequently decreases ATG5 (show ATG5 ELISA Kits) expression in both THP-1 (show GLI2 ELISA Kits) monocytoid cells and primary monocytes.

  3. calpains and calpastatin in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (show TAGLN ELISA Kits)-5HTT (show SLC6A4 ELISA Kits)(+) strain) PH, were investigated.

  4. Loss of CAST in angiogenic ECs facilitates mu (show JAK3 ELISA Kits)-calp (show STAT1 ELISA Kits)ain-induced SOCS3 degradati (show SOCS3 ELISA Kits)on, which amplifies p (show VEGFC ELISA Kits)athological angiogenesis through interleukin-6/STAT3/VEGF-C axis.

  5. We describe PLACK syndrome, as a clinical entity of defective epidermal adhesion, caused by loss-of-function mutations in calpastatin.

  6. Calpastatin binds with Cav1.2 (show CACNA1C ELISA Kits) amino acid motifs in a calcium dependent manner.

  7. Calpastatin gene (CAST) is not associated with late onset sporadic Parkinson's disease in the Han Chinese population.

  8. HER2 (show ERBB2 ELISA Kits) inhibited calpain-1 (show CAPN1 ELISA Kits) activity through upregulating calpastatin, an endogenous calpain inhibitor.

  9. The results suggest that calpain-2 (show CAPN2 ELISA Kits) and calpastatin expression is important in pancreatic cancers, influencing disease progression

  10. Neuronal overexpression of calpastatin modulates amyloid precursor protein (show APP ELISA Kits) processing in brains of transgenic beta-amyloid depositing mice.

Mouse (Murine) Calpastatin (CAST) interaction partners

  1. calpains and calpastatin in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (show TAGLN ELISA Kits)-5HTT (show SLC6A4 ELISA Kits)(+) strain) PH, were investigated.

  2. Defective scar formation after myocardial infarction in calpastatin transgenic mice was associated with blunted CD4 (show CD4 ELISA Kits)(+) T-cell and M2-macrophage recruitment.

  3. Over-expression of Cast inhibits calpain activation and attenuates post-infarction myocardial remodeling.

  4. EC-specific transgenic CAST downregulated JAK (show JAK3 ELISA Kits)/STAT (show STAT1 ELISA Kits) signals, upregulated SOCS3 (show SOCS3 ELISA Kits), and depleted VEGF-C (show VEGFC ELISA Kits), counteracting unstable pathological neovessels and disease progression in tumors and oxygen-induced retinopathy lesions in mice.

  5. Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-synuclein processing, aggregation and synaptic impairment in transgenic mice.

  6. We observed that ischemia induction results in increased expression of CaN, Calp and Calpn.

  7. Over-expression of calpastatin enhances doxorubicin-induced cardiac injuries through calpain inhibition.

  8. The calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma.

  9. Data show that genetic deficiency of calpastatin (CS) augmented Abeta (show APP ELISA Kits) amyloidosis, tau phosphorylation, microgliosis, and somatodendritic dystrophy, and increased mortality in amyloid precursor protein (APP (show APP ELISA Kits)) transgenic mice.

  10. PIN1 apparently restrains the ability of calpastatin to inhibit calpain, maintaining calpain activity in endothelial cells.

Cow (Bovine) Calpastatin (CAST) interaction partners

  1. Most heifer reproductive traits were not significantly affected by CAST and CAPN1 (show CAPNL1 ELISA Kits) markers that are widely used to improve beef tenderness by selection and breeders should not be concerned with how these markers affect reproduction and other heifer traits with the possible exception of CAPN1 (show CAPNL1 ELISA Kits) effects on calving date.

  2. The calpastatin gene (CAST), which is located on bovine chromosome 7 (BTAU7), is considered a strong functional candidate for meat tenderness in livestock species.

  3. The suppression of calpastatin resulted in the increased expression of mu-calpain (show CAPNL1 ELISA Kits), caspases, and HSPs which in turn regulate apoptotic cell death.

  4. This work is supportive of the importance of CAPN1 (show CAPNL1 ELISA Kits) and CAST for mean tenderness in beef.

  5. bovine CAPN-CAST interaction were well reflected in the geometry between the pharmacophore features and its shape constraints identified using our modeled bovine CAPN1 (show CAPNL1 ELISA Kits)/CAST4 complex structures

  6. CAST binds and inhibits CAPN via its CAPN-inhibitor domains(CAST1-4) .CAST4 docks near the flexible active site of CAPN1 (show CAPNL1 ELISA Kits), conformational changes at the interaction site after binding could be directly related to CAST4 inhibitory activity.

  7. This work confirms the importance of CAPN1 (show CAPNL1 ELISA Kits) and CAST for tenderness in beef, provides a new effect of CAST on beef tenderness, and questions the utility of GHR (show GHR ELISA Kits) as a selection marker for beef quality.

  8. The association of single nucleotide polymorphisms in calpastatin with muscle tenderness was studied.

  9. Association of polymorphisms in calpain 1 (show CAPN1 ELISA Kits), (mu/I) large subunit, calpastatin, and cathepsin D (show CTSD ELISA Kits) genes with meat quality traits in double-muscled Piemontese cattle.

  10. The CAST28 genotypes showing allele frequencies of C (0.429) and T (0.571) were significantly associated with calpastatin activity and Warner-Bratzler Shear Force in beef.

Pig (Porcine) Calpastatin (CAST) interaction partners

  1. CT1 (show SLC6A8 ELISA Kits) decreases cell death through a mechanism related to Stat3 (show STAT3 ELISA Kits) and Akt (show AKT1 ELISA Kits) phosphorylation and activation of calpastatin in D-galactosamine-treated hepatocytes.

  2. CAST gene affected post-mortem activation time of calpain and drip loss.

  3. The quality of meat influenced by RYR1 (show RYR1 ELISA Kits) genotype may be modified by the simultaneous influence of genotype as regards the CAST locus

  4. The effect of the beta-adrenergic agonist clenbuterol and porcine ST (pST (show SULT1A1 ELISA Kits)) treatment on calpastatin promoter usage in vivo and in vitro are reported.

  5. The Decreased expression of calpastatin mRNA during development is highly correlated with muscle protein accumulation in neonatal Sus scrofa.

Calpastatin (CAST) Antigen Profile

Antigen Summary

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with Calpastatin (CAST) ELISA Kits

  • calpastatin (CAST) antibody
  • calpastatin (Cast) antibody
  • calpastatin S homeolog (cast.S) antibody
  • calpastatin (cast) antibody
  • calpastatin (VDBG_09182) antibody
  • Calpastatin (ical) antibody
  • BS-17 antibody
  • calp3 antibody
  • cast antibody
  • DKFZp469E0716 antibody
  • sb:cb966 antibody
  • zgc:194249 antibody

Protein level used designations for Calpastatin (CAST) ELISA Kits

calpain inhibitor , sperm BS-17 component , calpastatin type III , calpastatin isoform III , calpastatin type I , calpastatin type II , calpastatin , Calpastatin , calpastatin-like

831 Homo sapiens
12380 Mus musculus
25403 Rattus norvegicus
281039 Bos taurus
397135 Sus scrofa
398115 Xenopus laevis
427121 Gallus gallus
443364 Ovis aries
462348 Pan troglodytes
479148 Canis lupus familiaris
563084 Danio rerio
703623 Macaca mulatta
9528399 Verticillium alfalfae VaMs.102
100009098 Oryctolagus cuniculus
100073225 Equus caballus
100136674 Oncorhynchus mykiss
100145371 Xenopus (Silurana) tropicalis
100174647 Pongo abelii
100380407 Salmo salar
100391897 Callithrix jacchus
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