anti-Calsyntenin 1 (CLSTN1) Antibodies

Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Additionally we are shipping Calsyntenin 1 Proteins (14) and Calsyntenin 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLSTN1 65945 Q9EPL2
CLSTN1 22883 O94985
CLSTN1 313717 Q6Q0N0
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Top anti-Calsyntenin 1 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CLSTN1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human kidney 100 μL 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of CLSTN1 using LOVO whole cell lysates ABIN6278136 at 1/100 staining Mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB Western blot analysis in 293 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-CS1 / CLSTN1 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this ... 100 μL 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of human CLSTN1 in human kidney with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human CLSTN1 in human brain with rabbit polyclonal antibody (0.2 µg/mL, formalin-fixed paraffin embedded sections). 100 μL 14 to 16 Days
$247.82
Details
Human Rabbit Un-conjugated WB Calsyntenin 1 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details
Human Rabbit Un-conjugated WB   100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB CLSTN1 MaxPab rabbit polyclonal antibody. Western Blot analysis of CLSTN1 expression in human kidney. Western Blot analysis of CLSTN1 expression in transfected 293T cell line by CLSTN1 MaxPab polyclonal antibody.Lane 1: CLSTN1 transfected lysate(108.70 KDa).Lane 2: Non-transfected lysate. 100 μg 11 to 12 Days
$425.71
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL 11 to 16 Days
$658.43
Details
Human Rabbit Un-conjugated IHC, WB   100 μL 11 to 14 Days
$551.83
Details

More Antibodies against Calsyntenin 1 Interaction Partners

Zebrafish Calsyntenin 1 (CLSTN1) interaction partners

  1. Our results suggest a model in which Clstn-1 patterns separate axonal compartments and define their ability to branch by directing trafficking of specific endosomes.

Mouse (Murine) Calsyntenin 1 (CLSTN1) interaction partners

  1. These results indicate that regulated intramembrane proteolysis of Alca by gamma-secretase regulates APP trafficking and the production of Abeta in vivo.

  2. these results highlight a key role for calsyntenin-1 in the transport of NMDA receptors to synaptic targets, which is necessary for the maturation of neuronal circuits during early development.

  3. Alcalpha is efficiently processed in part to minimize the inappropriate peripheral retention of kinesin-1

  4. Immunoisolated calsyntenin-1 organelles from murine brain homogenates; determined their proteome by MS. Found calsyntenin-1 organelles are endowed with components of the endosomal trafficking machinery and contained the beta-amyloid precursor protein (APP).

  5. Phosphorylation of KLC1 at serine 460 modulates binding and trafficking of calsyntenin-1.

  6. Calsyntenin-1 links a certain type of vesicular and tubulovesicular organelles to the Kinesin-1 motor.

  7. The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport.

Human Calsyntenin 1 (CLSTN1) interaction partners

  1. Results suggests that APP partially compensates for defective Alcalpha in anterograde transport by providing an alternative cargo receptor for kinesin-1.

  2. Calsyntenin-1 contributes to the early stages of the hepatitis C virus replication cycle and the formation of the replication complex.

  3. Increased plasma p3-Alcalpha35, a major fragment of alcalpha1, may indicate an endophenotype in Alzheimer's disease patients with progressive cognitive impairment.

  4. Increased plasma p3-alcadein (alc) alpha, evident in the early stages of cognitive impairment, suggests that alc metabolites are useful plasma biomarkers of Alzheimer's disease.

  5. findings show that calsyntenin-1 is reduced in Alzheimer's disease brains and that the extent of this reduction correlates with increased amyloid-beta

  6. CLSTN1 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.

  7. Phosphorylation of KLC1 at serine 460 modulates binding and trafficking of calsyntenin-1.

  8. Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation [alcalpha1, alcbeta, alcgamma]

Calsyntenin 1 (CLSTN1) Antigen Profile

Protein Summary

Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2- mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1- binding. May modulate calcium-mediated postsynaptic signals (By similarity).

Gene names and symbols associated with anti-Calsyntenin 1 (CLSTN1) Antibodies

  • calsyntenin 1 (CLSTN1) antibody
  • calsyntenin 1 (clstn1) antibody
  • calsyntenin 3 (clstn3) antibody
  • beta-catenin-interacting protein 1 (LOC100356725) antibody
  • calsyntenin-1 (LOC100435584) antibody
  • calsyntenin 1 (Clstn1) antibody
  • beta-catenin-interacting protein 1 (LOC479600) antibody
  • 1810034E21Rik antibody
  • ALC-ALPHA antibody
  • alcalpha1 antibody
  • alcalpha2 antibody
  • CALSYNTENIN-1 antibody
  • CDHR12 antibody
  • clstn1 antibody
  • Cst-1 antibody
  • CSTN1 antibody
  • fm67g03 antibody
  • PIK3CD antibody
  • wu:fk52g02 antibody
  • wu:fm67g03 antibody
  • XB31alpha antibody
  • zgc:56528 antibody
  • zgc:153744 antibody

Protein level used designations for anti-Calsyntenin 1 (CLSTN1) Antibodies

calsyntenin-1 , calsyntenin 1 , calsyntenin 3 , calsyntenin-1-like , alc-alpha , alcadein alpha , alcadein-alpha , alcadein alpha 1 , alzheimer-related cadherin-like protein , cadherin-related family member 12 , non-classical cadherin XB31alpha , non-classical cadherin XB31alpha1

GENE ID SPECIES
395372 Gallus gallus
722304 Macaca mulatta
777737 Danio rerio
100145668 Xenopus (Silurana) tropicalis
100356725 Oryctolagus cuniculus
100435584 Pongo abelii
100611252 Pan troglodytes
65945 Mus musculus
22883 Homo sapiens
313717 Rattus norvegicus
479600 Canis lupus familiaris
100520617 Sus scrofa
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