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Calsyntenin 1 antibody (N-Term)

CLSTN1 Reactivity: Human WB Host: Rabbit Polyclonal RB38737 unconjugated
Catalog No. ABIN1539080
  • Target See all Calsyntenin 1 (CLSTN1) Antibodies
    Calsyntenin 1 (CLSTN1)
    Binding Specificity
    • 15
    • 13
    • 8
    • 2
    • 1
    • 1
    • 1
    AA 15-42, N-Term
    Reactivity
    • 39
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 39
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Calsyntenin 1 antibody is un-conjugated
    Application
    • 39
    • 19
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CLSTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human CLSTN1.
    Clone
    RB38737
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CLSTN1 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    CLSTN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    Calsyntenin 1 (CLSTN1)
    Alternative Name
    CLSTN1 (CLSTN1 Products)
    Synonyms
    CALSYNTENIN-1 antibody, fm67g03 antibody, wu:fk52g02 antibody, wu:fm67g03 antibody, zgc:153744 antibody, zgc:56528 antibody, clstn1 antibody, 1810034E21Rik antibody, Cst-1 antibody, Cstn1 antibody, ALC-ALPHA antibody, CDHR12 antibody, CSTN1 antibody, PIK3CD antibody, XB31alpha antibody, alcalpha1 antibody, alcalpha2 antibody, calsyntenin 1 antibody, calsyntenin 3 antibody, beta-catenin-interacting protein 1 antibody, calsyntenin-1 antibody, CLSTN1 antibody, clstn1 antibody, clstn3 antibody, LOC100356725 antibody, LOC100435584 antibody, Clstn1 antibody, LOC479600 antibody
    Background
    Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity).
    Molecular Weight
    109793
    Gene ID
    22883
    NCBI Accession
    NP_001009566, NP_055759
    UniProt
    O94985
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