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The product of CALU is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. Additionally we are shipping Calumenin Kits (49) and Calumenin Antibodies (49) and many more products for this protein.
Showing 10 out of 21 products:
The Calumenin modulates Sarco/Endoplasmic reticulumCa2+ATPase (SERCA (show ATP2A3 Proteins)) pump activity without drastically affecting ER-Ca(2 (show CA2 Proteins)+) concentration.
irradiated tumor cells were observed to significantly up-regulate the expression of calcium-binding proteins CALM1, CALU, and RCN1 (show RCAN1 Proteins), suggesting important roles for these mediators in promoting irradiated tumor cell survival during hypoxia
Calu-15, a novel isoform of Calu with phosphorylation-dependent nuclear localization, has a critical role in promoting filopodia formation and cell migration by upregulating the GDF-15 (show GDF15 Proteins) transcription.
Results provide direct evidence for the involvement of CALU and LGALS3BP as potential negative regulators in the virus-triggered induction of the typeI interferons.
Results show that OSBPL5 (show OSBPL5 Proteins) and CALU were expressed at higher levels in the lung tissues of metastasis-positive cases than that in the metastasis-negative cases suggesting they can promote invasiveness of lung cancer cells.
CALU polymorphism A29809G affects calumenin availability involving vascular calcification
Calumenin is characterized as a charged protein exhibiting close similarity with intrinsically disordered proteins and is hypothesized to regulate F508del-CFTR (show CFTR Proteins) folding by electrostatic effects.
Calumenin is a new CFTR (show CFTR Proteins) chaperone.
Study found the secretion of calu-1/2-EGFP required microtubule integrity, and that calu-1/2-EGFP-containing vesicles were transported by the motor proteins Kif5b (show KIF5B Proteins) and cytoplasmic dynein (show DYNC1H1 Proteins).
Quantitative PCR assays for VKORC1 (show VKORC1 Proteins), CYP4F2, GGCX (show GGCX Proteins) and CALU identified two copies in all populations.
Extracellular calumenin regulates fibulin-1 to have crucial roles in ERK1/2 signaling and cell migration.
This study points to a possible important role of calumenin in migration and differentiation of neurons
Regions of 132-222 amino acids of calumenin and 853-892 amino acids of SERCA2 (show ATP2A2 Proteins) are the major binding partners.
The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.
IEF SSP 9302
, crocalbin-like protein
, multiple EF-hand protein
, calumenin homologue