CALU Protein (AA 20-315) (His tag)
-
- Target See all CALU Proteins
- CALU (Calumenin (CALU))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-315
-
Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This CALU protein is labelled with His tag.
- Purpose
- Recombinant Human Calumenin Protein (aa 20-315, His Tag)
- Sequence
- Lys20-Phe315
- Characteristics
- Recombinant Human Calumenin is produced by our Mammalian expression system and the target gene encoding Lys20-Phe315 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CALU Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- CALU (Calumenin (CALU))
- Alternative Name
- Calumenin (CALU Products)
- Synonyms
- 9530075H20Rik Protein, Cbp50 Protein, Rcn Protein, crocalbin Protein, MGC78837 Protein, calumenin Protein, calumenin L homeolog Protein, calumenin homologue Protein, CALU Protein, Calu Protein, calu Protein, calu.L Protein, calumenin Protein, CpipJ_CPIJ002187 Protein, Tsp_00516 Protein
- Background
-
Background: Calumenin is a secreted calcium-binding protein that belongs to the CREC family. Calumenin contains six EF-hand domains and is expressed at high levels in the heart, placenta and skeletal muscle. Human Calumenin is synthesized as a 315 amino acid precursor that contains a 19 amino acid signal sequence, and a 296 amino acid mature chain. Calumenin localizes to the endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) of mammalian tissues which plays a role in ER functions as protein folding and sorting. Calumenin is involved in the regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit γ-carboxylase GGCX.
Synonym: Calumenin, Crocalbin, IEF SSP 9302, CALU
- Molecular Weight
- 36.0 kDa
-