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Carcinoembryonic antigen (CEA\; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. Additionally we are shipping CEACAM6 Antibodies (110) and CEACAM6 Kits (9) and many more products for this protein.
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CEACAM6 promoted oral squamous cell carcinoma cell invasion, migration, cytoskeletal rearrangement, and metastasis via interaction with EGFR (show EGFR Proteins) and enhancing it activation.
Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1 (show CEACAM1 Proteins), CEACAM3 (show CEACAM3 Proteins), CEACAM5 (show CEACAM5 Proteins) or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA (show S100A8 Proteins) into host cells.
Here, the authors identify members of the carcinoembryonic antigen (show CEACAM5 Proteins)-related cell adhesion molecule (show MCAM Proteins) (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1 (show CEACAM1 Proteins), CEACAM3 (show CEACAM3 Proteins), CEACAM5 (show CEACAM5 Proteins) and CEACAM6.
CD66c (KOR (show OPRK1 Proteins)-SA3544) antigen expression of leukemic blasts in pediatric acute myeloid leukemia (show BCL11A Proteins) with TLS/FUS (show FUS Proteins)-ERG (show ERG Proteins) fusion transcript
Data suggest that the expression of these TSPAN8 (show TSPAN8 Proteins), LGALS4 (show LGALS4 Proteins), COL1A2 (show COL1A2 Proteins) and CEACAM6 in the whole blood may be useful in the detection of colorectal cancer (CRC (show CALR Proteins)).
a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO (show MPO Proteins), CEACAM8, CRISP3 (show CRISP3 Proteins), MS4A3 (show MS4A3 Proteins), CEACAM6, HEMGN, and MMP8 (show MMP8 Proteins)
In enterocytic C2BBe1 cells, Candida albicans caused a transient tyrosine phosphorylation of CEACAM1 (show CEACAM1 Proteins) and induced higher expression of membrane-bound CEACAM1 (show CEACAM1 Proteins) and soluble CEACAM6.
show the upregulation of the tumor-associated antigens CEACAM5 (show CEACAM5 Proteins)/6 by trans-signaling of the pro-inflammatory cytokine IL-6 (show IL6 Proteins)
Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another.
vaccination with recombinant attenuated Salmonella harboring the CEACAM6 and 4-1BBL (show TNFSF9 Proteins) gene efficiently increased the number of CD3 (show CD3 Proteins)+CD8 (show CD8A Proteins)+ TIL (show TLR1 Proteins) and NK cells, decreased the number of FOXP3 (show FOXP3 Proteins) cells and inhibited the development of DMH (show DST Proteins)-induced colorectal cancer
Carcinoembryonic antigen (CEA\; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988
carcinoembryonic antigen-related cell adhesion molecule 6
, non-specific crossreacting antigen
, normal cross-reacting antigen