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CEACAM6 Protein (Fc Tag)

MALS verified CEACAM6 Origin: Human Host: HEK-293 Cells Recombinant 95,00 %
Catalog No. ABIN7448006
  • Target See all CEACAM6 Proteins
    CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
    Protein Type
    Recombinant
    Origin
    • 14
    • 1
    Human
    Source
    • 9
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CEACAM6 protein is labelled with Fc Tag.
    Purpose
    Human CEACAM-6 / CD66c Protein, Fc Tag (MALS verified)
    Sequence
    Lys 35 - Gly 320
    Characteristics
    Human CEACAM-6, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Lys 35 - Gly 320 (Accession # P40199-1).
    Purity
    95,00 %
    Endotoxin Level
    1.0 EU per μg
    Grade
    MALS verified
    Top Product
    Discover our top product CEACAM6 Protein
  • Comment

    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 57.7 kDa. The protein migrates as 75-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
    Alternative Name
    CEACAM-6 (CEACAM6 Products)
    Synonyms
    CD66c Protein, CEAL Protein, NCA Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, carcinoembryonic antigen related cell adhesion molecule 6 Protein, Ceacam6 Protein, CEACAM6 Protein
    Background
    Synonyms:CEACAM6,CD66c,CEAL,NCA,Description:Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) is also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM 6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to E-selectin, galectins and some bacterial fimbrae. CEACAM-6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
    Molecular Weight
    57.7 kDa
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