anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase Antibodies

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis.

Data Quality
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Type
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    Primary antibodies
Antigen
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Reactivity
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  • 11
  • 7
  • 1
  • 1
Application
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  • 15
  • 5
  • 2
  • 2
Host
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  • 9
  • 5
  • 3
Clonality
  • 26
  • 4
Clone
  • 3
  • 1
Binding Specificity
  • 7
  • 4
  • 3
  • 3
  • 3
Conjugate
  • 20
  • 4
  • 2
  • 1
  • 1
Isotype
  • 15
  • 2
  • 1
  • 1
  • 1
Format
  • 22
  • 6
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Application IF/ICC, IHC, IP, WB
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Application ELISA
Order details Cat. No. ABIN563648
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100 μg
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Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) Antigen Profile

Protein Summary

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins\; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.

Gene names and symbols associated with CILP

  • cartilage intermediate layer protein (CILP) antibody
  • cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp) antibody
  • cartilage intermediate layer protein (Cilp) antibody
  • cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (cilp) antibody
  • cartilage intermediate layer protein 1 (LOC100336614) antibody
  • 9830114D16 antibody
  • C130036G17Rik antibody
  • CILP antibody
  • CILP-1 antibody
  • HsT18872 antibody
  • im:7137994 antibody
  • NTPPH antibody

Protein level used designations for CILP

cartilage intermediate layer protein 1 , cartilage intermediate layer protein 1 C1 , cartilage intermediate layer protein 1 C2 , cartilage intermediate-layer protein , CILP-1 , nucleotide pyrophosphohydrolase , cartilage intermediate layer protein, nucleotide pyrophosphohydrolase , cartilage intermediate layer protein 1-like , CILP protein

GENE ID SPECIES
8483 Homo sapiens
214425 Mus musculus
315761 Rattus norvegicus
397672 Sus scrofa
415533 Gallus gallus
453514 Pan troglodytes
487603 Canis lupus familiaris
100224477 Taeniopygia guttata
100390902 Callithrix jacchus
100475451 Ailuropoda melanoleuca
100541878 Meleagris gallopavo
100586830 Nomascus leucogenys
553329 Danio rerio
100336614 Bos taurus
100053337 Equus caballus
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