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Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Additionally we are shipping CASS4 Kits (5) and CASS4 Proteins (3) and many more products for this protein.
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The results of this study showed that Cas scaffolding protein family member 4 with protein tyrosine kinase 2 and their significant role in the activation of downstream signaling pathways in Alzheimer's disease.
High expression of CASS4 is associated with invasion in non-small cell lung cancer.
EFS and CASS4 protein function in the context of the larger CAS family group. [Review]
Hepl is overexpressed in the nucleus and aberrantly accumulates in the cytoplasm of non-small cell lung cancer cells, and Hepl may play a role in the progression of lung cancer, including lymph node metastasis and TNM stage.
HEPL maintains Cas family function in localization to focal adhesions, as well as regulation of FAK activity, focal adhesion integrity, and cell spreading.
Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity).
, HEF1-EFS-p130Cas-like protein
, cas scaffolding protein family member 4
, likely orthologue of H. sapiens chromosome 20 open reading frame 32 (C20orf32)