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Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Additionally we are shipping CASS4 Kits (5) and CASS4 Proteins (3) and many more products for this protein.
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High expression of CASS4 is associated with invasion in non-small cell lung cancer.
EFS (show EFS Antibodies) and CASS4 protein function in the context of the larger CAS (show CSE1L Antibodies) family group. [Review]
Hepl is overexpressed in the nucleus and aberrantly accumulates in the cytoplasm of non-small cell lung cancer cells, and Hepl may play a role in the progression of lung cancer, including lymph node metastasis and TNM (show ODZ1 Antibodies) stage.
HEPL maintains Cas (show CSE1L Antibodies) family function in localization to focal adhesions, as well as regulation of FAK (show PTK2 Antibodies) activity, focal adhesion integrity, and cell spreading.
Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity).
, HEF1-EFS-p130Cas-like protein
, cas scaffolding protein family member 4
, likely orthologue of H. sapiens chromosome 20 open reading frame 32 (C20orf32)