Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) ELISA Kits

CASP14 encodes a member of the cysteine-aspartic acid protease (caspase) family. Additionally we are shipping Caspase 14, Apoptosis-Related Cysteine Peptidase Antibodies (115) and Caspase 14, Apoptosis-Related Cysteine Peptidase Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CASP14 12365 O89094
CASP14 299587  
CASP14 23581 P31944
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Top Caspase 14, Apoptosis-Related Cysteine Peptidase ELISA Kits at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$663.16
Details
Mouse 0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$720.00
Details
Rat 0.117 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
$720.00
Details
Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Rabbit 0.1 ng/mL 1.0-25 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Chicken 1.875 ng/mL 3.125-200 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Cow 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details

Top referenced Caspase 14, Apoptosis-Related Cysteine Peptidase ELISA Kits

  1. Human CASP14 ELISA Kit for Sandwich ELISA - ABIN415001 : Jung, Choi, Lee, Kim, Hwang, Choi: Pyrrolidone carboxylic acid levels or caspase-14 expression in the corneocytes of lesional skin correlates with clinical severity, skin barrier function and lesional inflammation in atopic dermatitis. in Journal of dermatological science 2014 (PubMed)
    Show all 2 Pubmed References

More ELISA Kits for Caspase 14, Apoptosis-Related Cysteine Peptidase Interaction Partners

Mouse (Murine) Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) interaction partners

  1. Mesotrypsin generated saposins A-D from prosaposin, and mature caspase-14 contributed to this process by activating mesotrypsinogen to mesotrypsin. Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  2. caspase-14 overexpression is not the cause of utricle formation

  3. Caspase-14-deficient mice are more prone to the development of parakeratosis.

  4. Mere impairment of filaggrin degradation by loss of caspase 14 does not influence the inflammatory threshold of atopic dermatitis.

  5. Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin.

  6. Transcript profiling studies identified caspase-14 as a novel downstream target of Gata-3, in keeping with its roles in differentiation and tumorigenesis.

  7. We investigated whether cardiac autonomic control is impaired during sleep in ob/ob mice with morbid obesity caused by congenital leptin deficiency.

  8. processing of caspase 14 in epidermal differentiation

  9. SH2-B dramatically enhanced leptin-stimulated tyrosine phosphorylation of IRS1 and IRS2 in human and mouse cells (this is supposed to be a NEWENTRY for mice--SH2-B).

  10. Caspase-14, but not caspase-3 activation coincides temporally and spatially with embryonic KC differentiation, suggesting a role for caspase-14 in terminally differentiated KC.

  11. The skin of caspase-14-deficient mice was shiny and lichenified, indicating an altered stratum-corneum composition. It contained significantly more alveolar keratohyalin F-granules, the profilaggrin stores.

  12. permeability barrier requirements coordinately drive both the generation of the stratum corneum lipid-enriched extracellular matrix and the transformation of granular cells into corneocytes, in an SP- and Casp-14-dependent manner, signaled by PAR2

Human Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) interaction partners

  1. High CASP14 expression is a marker of breast cancer aggressiveness in association with proliferation, TNBC phenotype, and cancer stemness.

  2. overexpression of S100A7 in A431 skin squamous carcinoma cells significantly promoted cell proliferation in vitro and tumor growth in vivo, whereas it suppressed the expression of GATA-3 and caspase-14

  3. caspase-14 contributes to retinal pigment epithelium cell barrier disruption under hyperglycemic conditions.

  4. Caspase-14 was decreased in inflammatory lesions compared to non-lesion in atopic dermatitis. The amount of caspase-14 in the lesions correlated with clinical severity as determined by eczema area and severity index score and the skin barrier functions.

  5. Mesotrypsin generated saposins A-D from prosaposin, and mature caspase-14 contributed to this process by activating mesotrypsinogen to mesotrypsin. Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  6. partial loss of caspase 14 is not associated with dedifferentiation in neoplastic lesions of the oral mucosa

  7. genetic polymorphisms in AICDA and CASP14 are associated with risk for brain tumor in Korean children.

  8. Suggest caspase-14 is a marker of human skin differentiation during development.

  9. Results suggest that caspase-14 may interact with GCM1 to participate in syncytiotrophoblast differentiation during placental development.

  10. ceramides, an important structural lipid, stimulate caspase-14 expression, coordinating formation of lipid lamellar membranes with the formation of corneocytes

  11. Caspase-14 might play a significant role in the pathogenesis of diabetic retinopathy by accelerating retinal endothelial and epithelial cells death.

  12. regulation of procaspase-14 maturation during terminal differentiation is a unique two-step process involving KLK7 and an activation intermediate of caspase-14.

  13. genetic polynorphism is associated with the risk of childhood leukemia

  14. A strong association was evident between GATA-3 and caspase-14 expression in preinvasive ductal carcinoma in situ samples, where GATA-3 also displayed prognostic significance

  15. Regulation of caspase 14 levels provides a possible link between impaired skin barrier function and inflammatory reactions in skin diseases such as atopic dermatitis and may offer an explanation to the skin barrier dysfunction in inflamed skin lesions.

  16. Casp-14 overexpression correlated with tumor stage, cell differentiation and lymphovascular involvement, suggesting that casp-14 was associated with tumor cell growth and metastatic potential.

  17. Caspase 14 is a cysteine protease and is inhibited by full-length LEKTI and 5 recombinant fragments of LEKTI to varied extents.

  18. Purification and characterization of active caspase-14 from human epidermis and development of the cleavage site-directed antibody

  19. Results imply that caspase-14 inhibits trophoblast differentiation.

  20. processing of caspase 14 in epidermal differentiation

Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) Antigen Profile

Antigen Summary

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Gene names and symbols associated with CASP14

  • caspase 14, apoptosis-related cysteine peptidase (CASP14) antibody
  • caspase 14 (Casp14) antibody
  • caspase 14 (CASP14) antibody
  • caspase-14-like (LOC485601) antibody
  • caspase-14 (LOC780455) antibody
  • CASP14 antibody
  • MICE antibody
  • mini-ICE antibody

Protein level used designations for CASP14

caspase 14 , CASP-14 , caspase-14 , apoptosis-related cysteine protease , caspase 14, apoptosis-related cysteine protease

GENE ID SPECIES
100012133 Monodelphis domestica
12365 Mus musculus
299587 Rattus norvegicus
100101622 Oryctolagus cuniculus
23581 Homo sapiens
100715745 Cavia porcellus
517658 Bos taurus
485601 Canis lupus familiaris
780455 Ovis aries
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