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Caspase inhibitor. Additionally we are shipping CARD16 Proteins (5) and many more products for this protein.
Showing 10 out of 20 products:
Human Polyclonal CARD16 Primary Antibody for ELISA - ABIN546774
Druilhe, Srinivasula, Razmara, Ahmad, Alnemri: Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins. in Cell death and differentiation 2001
Expression of NOX4/p22(phox) as well as ROS production is enhanced by IL-1beta. On the other hand, the use of NOX4 inhibitors decreased IL-1beta-induced collagenase synthesis by chondrocytes.
Caspase-1-mediated cell death is regulated, at least in part, by the balance of Rip2 and Cop; alterations of this balance may contribute to aberrant caspase-1-mediated pathogenesis in Huntington's disease.
Cop inhibition of cell death, at least to a certain extent, results from its interference with the activation of caspase-1 and caspase-4.
Caspase inhibitor. Acts as a regulator of procaspase- 1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro- inflammatory cytokine response. Also able to inhibit CASP1- mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
CARD only domain-containing protein 1
, CARD only protein
, caspase recruitment domain-containing protein 16
, caspase-1 dominant-negative inhibitor pseudo-ICE
, caspase-1 inhibitor COP
, pseudo interleukin-1 beta converting enzyme
, pseudo interleukin-1beta converting enzyme