anti-Cathepsin C (CTSC) Antibodies

The protein encoded by CTSC, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. Additionally we are shipping Cathepsin C Kits (33) and Cathepsin C Proteins (19) and many more products for this protein.

Gene Name	GeneID	UniProt
CTSC	1075	P53634
CTSC	13032	P97821
CTSC	25423	P80067

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Top anti-Cathepsin C Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN2788336	Cow	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN2788337	Human	Rabbit	Un-conjugated	IHC, WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN1536128	Human	Rabbit	Un-conjugated	ELISA, WB	100 μg	Log in to see	2 to 3 Days	$302.50	Details
ABIN1978154	Human	Goat	Un-conjugated	IHC (p), ELISA	50 μg	Log in to see	7 to 9 Days	$484.00	Details
ABIN611363	Cow	Rabbit	Un-conjugated	WB	50 μg	Log in to see	7 to 9 Days	$551.83	Details
ABIN1858542	Human	Rabbit	Un-conjugated	ICC, IHC, WB	100 μg	Log in to see	13 to 16 Days	$350.00	Details
ABIN1858543	Mouse	Rabbit	Un-conjugated	ICC, IHC, WB	100 μg	Log in to see	13 to 16 Days	$360.00	Details
ABIN2736597	Human	Rabbit	Un-conjugated	WB	100 μL	Log in to see	16 Days	$334.02	Details
ABIN1804604	Human	Mouse	Un-conjugated	IHC (p), ELISA, WB	50 μL	Log in to see	7 to 9 Days	$639.83	Details
ABIN3181788	Human	Rabbit	Un-conjugated	ELISA, WB	100 μL	Log in to see	16 Days	$181.73	Details

CTSC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes	Applications	Host	Clonality	Conjugate
Human	, , ,	, ,	,	, , , , , , , , , , , , , , , ,
Mouse (Murine)	,			, , , , , , , , , , , , ,
Rat (Rattus)	,			, , , , , , , , , , , , ,

More product categories related to Cathepsin C Antibody

More Antibodies against Cathepsin C Interaction Partners

Human Cathepsin C (CTSC) interaction partners

A compound mutation consisting of a large deletion and a nonsense mutation, which provides a new insight in the mutation type of CTSC gene.
CTSC gene missense mutation is responsible for Papillo- Lefevre syndrome in a Turkish family.
analysis of fluorescent substrates provides a detailed S' specificity study of cathepsin C
Mutation screening of the CTSC gene from the two patients revealed the presence of the same homozygous nonsense mutation in Papillon-Lefevre syndrome and Haim-Munk syndromes. Phenotypic variants of the same rare disease caused by mutations of the cathepsin C (CTSC) gene.
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
CTSC was associated with albuminuria in type 2 diabetes patients.
Homozygous mutation 901G>A in exon 7 of CTSC gene is associated with Papillon-Lefevre syndrome.
Results identify a missense mutation in CTSC gene that segregate within a family with Papillon-Lefevre syndrome.
Papillon-Lefevre syndrome cause by homozygous nonsense mutation of cathepsin C gene.
CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

Mouse (Murine) Cathepsin C (CTSC) interaction partners

During the active remyelinating phase, both CysF knockdown (CysFKD) and microglial-selective CatC overexpression (CatCOE) showed a worsening of the demyelination in Plp (show C3 Antibodies)(4e/-) transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process.
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
Double immunofluorescence analysis showed that CTLA-2alpha was co-localized with cathepsin L (show CTSL1 Antibodies), cathepsin C, and TINAGL1 (show TINAGL1 Antibodies) in placenta.
CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.
Data indicate that all-trans retinoic acid (ATRA), which induces miR (show MLXIP Antibodies)-23a expression, decreases cathepsin C (CTSC) expression and granzyme B activity leading to impaired NK cell cytotoxicity.
These results establish that DPPI is a major determinant of survival following Klebsiella pneumoniae lung infection and suggest that the survival disadvantage in DPPI(+/+) mice is in part due to processing of surfactant protein D (show SFTPD Antibodies) by DPPI.
found no significant role for CtsC during mammary carcinogenesis but revealed squamous carcinogenesis to be functionally dependent on CtsC
Late stage cathepsin C, CXCL13 (show CXCL13 Antibodies) and Ki-67 (show MKI67 Antibodies) overexpression correlate with regional neuropathology in a bovine spongiform encephalopathy transgenic murine model.
Proinflammatory cytokines induce expression and release of cathepsin C in microglial cells during neuroinflammatory progression.
The production of IL-1beta (show IL1B Antibodies) by macrophages, neutrophils, and mast cells in vitro is dependent on caspase-1 (show CASP1 Antibodies) but not on cathepsin C.

Cathepsin C (CTSC) Antigen Profile

Protein Summary

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Cathepsin C (CTSC) Antibodies

cathepsin C (CTSC) antibody
cathepsin C L homeolog (ctsc.L) antibody
cathepsin C (ctsc) antibody
cathepsin C (TP03_0357) antibody
cathepsin C (CMU_003360) antibody
cathepsin CPC1 (CPC1) antibody
cathepsin C (NAEGRDRAFT_80477) antibody
cathepsin C (NAEGRDRAFT_37577) antibody
cathepsin C (Ctsc) antibody
cathepsin C (Smp_183330) antibody

AI047818 antibody
CATC antibody
cb912 antibody
CPPI antibody
DPP-I antibody
DPP1 antibody
DPPI antibody
HMS antibody
ik:tdsubc_1h2 antibody
JP antibody
JPD antibody
MGC69126 antibody
MGC107782 antibody
PALS antibody
PDON1 antibody
PLS antibody
sb:cb146 antibody
wu:fb34g12 antibody
wu:fj58d01 antibody

Protein level used designations for anti-Cathepsin C (CTSC) Antibodies

cathepsin J , dipeptidyl peptidase 1 , dipeptidyl peptidase I , dipeptidyl transferase , dipeptidyl-peptidase I , cathepsin C , dipeptidyl peptidase 1 isoform a preproprotein , DPPI , DPP-I , Dipeptidyl-peptidase 1 , dipeptidyl-peptidase 1 , dipeptidylpeptidase 1

GENE ID	SPECIES
1075	Homo sapiens
380203	Xenopus laevis
407938	Xenopus (Silurana) tropicalis
419014	Gallus gallus
451469	Pan troglodytes
705320	Macaca mulatta
3500364	Theileria parva strain Muguga
6997925	Cryptosporidium muris RN66
7899372	Toxoplasma gondii ME49
8851692	Naegleria gruberi strain NEG-M
8855504	Naegleria gruberi strain NEG-M
100172530	Pongo abelii
13032	Mus musculus
25423	Rattus norvegicus
352958	Bos taurus
403458	Canis lupus familiaris
100101594	Oryctolagus cuniculus
100714387	Cavia porcellus
101112686	Ovis aries
8346758	Schistosoma mansoni
368704	Danio rerio

Selected quality suppliers for anti-Cathepsin C (CTSC) Antibodies

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