anti-Ceramide Synthase 1 (CERS1) Antibodies

CERS1 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Additionally we are shipping Ceramide Synthase 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CERS1 10715 P27544
CERS1 93898 P27545
CERS1 290658  
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Top anti-Ceramide Synthase 1 Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Horse Rabbit Un-conjugated WB WB Suggested Anti-LASS1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 6 to 7 Days
$429.84
Details
Horse Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$581.17
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (31.61 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Cow Goat Un-conjugated WB   0.1 mg Log in to see 4 to 8 Days
$462.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 11 to 14 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB LASS1 polyclonal antibody (1 ug/mL) staining of human frontal cortex lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 11 to 12 Days
$374.67
Details
Human Rabbit Un-conjugated WB LASS1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$473.93
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 11 to 14 Days
$551.83
Details

Top referenced anti-Ceramide Synthase 1 Antibodies

  1. Human Polyclonal CERS1 Primary Antibody for ELISA, WB - ABIN564667 : Senkal, Ponnusamy, Rossi, Bialewski, Sinha, Jiang, Jazwinski, Hannun, Ogretmen: Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas. in Molecular cancer therapeutics 2007 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal CERS1 Primary Antibody for ELISA, WB - ABIN451734 : Venkataraman, Riebeling, Bodennec, Riezman, Allegood, Sullards, Merrill, Futerman et al.: Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a ... in The Journal of biological chemistry 2002 (PubMed)

More Antibodies against Ceramide Synthase 1 Interaction Partners

Human Ceramide Synthase 1 (CERS1) interaction partners

  1. Single nucleotide polymorphisms in the gene LASS1 associated with programmed cell death, providing a potential cellular mechanism for the effects on tissue damage and circulating Creatine kinase.

  2. This study highlights a close interaction between CLN5/CLN8 proteins, and their role in sphingolipid metabolism. Our findings suggest that CLN5p/CLN8p most likely are positive modulators of CerS1 and/or CerS2.

  3. Moreover, an alternatively spliced variant CerS1 mRNA (CerS1-2) was detected mainly in cancer cells or primary tumour tissues compared to controls, which was targeted by miR-574-5p for degradation

  4. The variation in LASS1 is functional, causing enhanced expression of the gene, and it contributes to healthy aging and greater survival in the tenth decade of life.

  5. The study suggests that diverse stresses initiate responses through different signaling pathways, which ultimately converge to regulate CerS1 localization.

  6. regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cel

  7. LAG1 and C18-ceramide have roles in the regulation of growth of HNSCC

Mouse (Murine) Ceramide Synthase 1 (CERS1) interaction partners

  1. The strong association of LCB levels with neuronal survival both in vivo and in vitro suggests high-level accumulation of LCBs is a possible underlying cause of the CerS1 deficiency-induced neuronal death.

  2. CerS1, -2, and -6 are hyperacetylated in the mitochondria of SIRT3-null mice.

  3. study is the first comparison of spatial distribution between SM molecular species and CerS isoforms, and revealed their distinct association in the brain.

  4. Data indicate that oxidized phospholipids (OxPLs)-induced ceramide synthases (CerS1-Cers6) activity in macrophages is responsible for the accumulation of ceramide.

  5. an essential function of CerS1-derived ceramide in the regulation of cerebellar development and neurodevelopmentally regulated behavior.

Arabidopsis thaliana Ceramide Synthase 1 (CERS1) interaction partners

  1. Findings indicate that AtORM1 and AtORM2 mediation of serine palmitoyltransferase (SPT) activity differentially regulates functionally distinct ceramide synthase activities as part of a broader sphingolipid homeostatic regulatory network.

  2. The role of At3g25540 in sphingolipid metabolism, mycotoxin resistance and cell death.

  3. Spontaneous cell death in the loh1 line is triggered either by the accumulation of free trihydroxy sphingoid bases or ceramide species with C(16) fatty acid.[LOH1]

Ceramide Synthase 1 (CERS1) Antigen Profile

Protein Summary

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.

Gene names and symbols associated with CERS1

  • ceramide synthase 1 (CERS1) antibody
  • ceramide synthase 1 (Cers1) antibody
  • TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein (LAG1) antibody
  • LAG1 antibody
  • LAG1 HOMOLOG 1 antibody
  • Lass1 antibody
  • LONGEVITY ASSURANCE GENE 1 antibody
  • to antibody
  • Uog-1 antibody
  • UOG1 antibody

Protein level used designations for CERS1

longevity assurance gene 1 , longevity assurance (LAG1, S. cerevisiae) homolog 1 , longevity assurance gene 1 protein homolog 1 , protein UOG-1 , upstream of GDF1 , LAG1 homolog, ceramide synthase 1 , LAG1 longevity assurance homolog 1 , longevity assurance homolog 1 , longevity assurance-like protein 1

GENE ID SPECIES
468773 Pan troglodytes
10715 Homo sapiens
615296 Bos taurus
93898 Mus musculus
290658 Rattus norvegicus
609789 Canis lupus familiaris
100525450 Sus scrofa
822140 Arabidopsis thaliana
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