anti-Cerebellin 1 Precursor (CBLN1) Antibodies

CBLN1 encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Additionally we are shipping CBLN1 Kits (20) and CBLN1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CBLN1 869 P23435
CBLN1 498922 P63182
CBLN1 12404 Q9R171
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Top anti-CBLN1 Antibodies at

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CBLN1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate 100 μL 2 to 3 Days
Cow Rabbit Un-conjugated WB Western blot analysis of Cerebellin 1 expression in HEK293T (A), SP2/0 (B), PC12 (C) whole cell lysates. 200 μL 13 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc cells, using CBLN1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB 50 μg 6 to 8 Days
Human Rabbit Un-conjugated IF, IHC, IHC (fro), IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with CBLN1 antibody ABIN214435 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Mouse small intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg 11 to 14 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Available
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6274994 staining HuvEc by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11 to 12 Days
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg 4 to 8 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 to 16 Days

Top referenced anti-CBLN1 Antibodies

  1. Human Polyclonal CBLN1 Primary Antibody for IF, WB - ABIN541486 : Mazzocchi, Andreis, De Caro, Aragona, Gottardo, Nussdorfer: Cerebellin enhances in vitro secretory activity of human adrenal gland. in The Journal of clinical endocrinology and metabolism 1999 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CBLN1 Primary Antibody for IHC (p), WB - ABIN541488 : Albertin, Malendowicz, Macchi, Markowska, Nussdorfer: Cerebellin stimulates the secretory activity of the rat adrenal gland: in vitro and in vivo studies. in Neuropeptides 2000 (PubMed)
    Show all 3 Pubmed References

More Antibodies against CBLN1 Interaction Partners

Human Cerebellin 1 Precursor (CBLN1) interaction partners

  1. Cbln1 and Cbln2 are co-expressed in the endolysosomal compartment of the thalamic neurons responsible for the synaptic alterations in striatum of Cbln1-null mice.

Mouse (Murine) Cerebellin 1 Precursor (CBLN1) interaction partners

  1. Cbln4 partially rescued and both glycosylation mutants completely rescued ataxia in cbln1-null mice

  2. Results show that Cbln1, Cbln2, and Cbln4 are abundantly expressed in nearly all brain regions, but exhibit strikingly different expression patterns and developmental dynamics. Using newly generated knockin reporter mice for Cbln2 and Cbln4, we find that Cbln2 and Cbln4 are not universally expressed in all neurons, but only in specific subsets of neurons.

  3. results suggest that gene and seizure interactions in ventral tegmental area glutamatergic neurons impair sociability by downregulating Cbln1, a key node in the expanding protein interaction network of autism genes

  4. Despites its well known role in motor coordination and motor learning, whether and how the cerebellum is involved in cognitive functions remains less clear. Cerebellin 1 (Cbln1) is highly expressed in the cerebellum and serves as an essential synaptic organizer. Although genes encoding Cbln1 and its receptor are associated with many psychiatric disorders, it remains unknown whether such cognitive impairments are caused by

  5. amplitude and frequency of mIPSCs were increased in cbln1-null cerebellar slices.

  6. This study provides evidence for involvement of Cbln1 in nociception and provides a platform for continued exploration of involvement of novel neuropeptides in the regulation of nociceptive transmission

  7. that neurons expressing Cblns 1, 2, and 4 tend to occupy different laminar positions within the dorsal spinal cord

  8. extracerebellar structures or remaining PF-PC synapses in cbln1(-/-) mice may be sufficient for the expression, maintenance, and extinction of its memory trace.

  9. Cbln1 released from parallel fiber Purkinje cells induces dynamic structural changes in parallel fibers.

  10. [review] The Cbln1-GluRdelta2 receptor complex is located at the cleft of parallel fiber-Purkinje cell synapses and bidirectionally regulates both presynaptic and postsynaptic differentiation.

  11. GluRdelta1 stimulated inhibitory synapse formation in the presence of Cbln1 or Cbln2

  12. Data show that Cbln1 and Cbln2, but not Cbln4, specifically bind to neurexin 1alpha and -beta and induce synaptogenesis in cerebellar, hippocampal and cortical neurons in vitro.

  13. These results suggest that Cbln1 and Cbln2 play a role in synapse formation of cortical neurons by interacting with NRXNs containing S4.

  14. Otolin 1 interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1 in the inner ear.

  15. Our observation that loss of Cbln1 leads to increased numbers of striatal medium spiny neurons' dendritic spines suggests that modulating thalamostriatal Cbln1 may be a novel means of improving symptoms or slowing progression in Parkinson's disease.

  16. the flap loop (Arg321-Trp339) in the NTD of GluD2 (GluD2-NTD) was identified as a crucial region for the binding to Cbln1 and the induction of presynaptic differentiation.

  17. Results suggest that GluRdelta2 mediates cerebellar synapse formation by interacting with presynaptic NRXNs through Cbln1.

  18. study found that Cbln1 binds directly to the N-terminal domain of glutamate receptor delta2 (GluD2); results indicate that the Cbln1-GluD2 complex is a unique synapse organizer that acts bidirectionally on both pre- and postsynaptic components

  19. the cleavages required to produce cerebellin influence the subunit stoichiometry of Cbln1 complexes

  20. In the developing brain, Cbln1 mRNA appeared as early as embryonic day 10-13, and exhibited transient up-regulation during the late embryonic and neonatal periods.

CBLN1 Antigen Profile

Protein Summary

This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland.

Gene names and symbols associated with CBLN1

  • cerebellin 3 precursor (cbln3) antibody
  • cerebellin 1 precursor (cbln1) antibody
  • cerebellin 1 precursor L homeolog (cbln1.L) antibody
  • cerebellin 1 precursor (CBLN1) antibody
  • cerebellin 1 precursor (Cbln1) antibody
  • cerebellin 1 precursor protein (Cbln1) antibody
  • AI323299 antibody
  • CBLN1 antibody
  • MGC145915 antibody
  • zgc:92807 antibody

Protein level used designations for CBLN1

Cerebellin-1 , cerebellin 1 , sghC1q01 , cerebellin 1 precursor , cerebellin-1 , precerebellin , cerebellin 1 precursor protein , Precerebellin , precerebellin 1 , brain protein D3

100195323 Salmo salar
436793 Danio rerio
495934 Xenopus laevis
745969 Pan troglodytes
771265 Gallus gallus
779761 Xenopus (Silurana) tropicalis
869 Homo sapiens
498922 Rattus norvegicus
618604 Bos taurus
100127148 Sus scrofa
611712 Canis lupus familiaris
12404 Mus musculus
100355335 Oryctolagus cuniculus
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