anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) Antibodies

CCRL2 encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Additionally we are shipping CCRL2 Proteins (4) and CCRL2 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCRL2 316019  
CCRL2 9034 O00421
CCRL2 54199 O35457
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Top anti-CCRL2 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CCRL2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysate CCRL2 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CCRL2 expression in HeLa (A), mouse heart (B), mouse brain (C), rat brain (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HepG2 cells, using CCRL2 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of COS7 cells, using CCRL2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB CCRL2 Antibody (Center) western blot analysis in 293 cell line lysates (35µg/lane).This demonstrates the CCRL2 antibody detected the CCRL2 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IF, WB 100 μL Available
$363.46
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-CCRL2 antibody ABIN1048411 IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-CCRL2 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of CCRL2 using A549 whole cell lysates ABIN6278557 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB CCRL2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CCRL2 antibody detected the CCRL2 protein (arrow). 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis in 293 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details

Top referenced anti-CCRL2 Antibodies

  1. Human Monoclonal CCRL2 Primary Antibody for CyTOF, FACS - ABIN4899081 : Leick, Catusse, Follo, Nibbs, Hartmann, Veelken, Burger: CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B. in Immunology 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal CCRL2 Primary Antibody for CyTOF, FACS - ABIN4899082 : Hartmann, Leick, Ewers, Diefenbacher, Schraufstatter, Honczarenko, Burger: Human B cells express the orphan chemokine receptor CRAM-A/B in a maturation-stage-dependent and CCL5-modulated manner. in Immunology 2008 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal CCRL2 Primary Antibody for FACS - ABIN4895455 : Vinci, Bastone, Schiarea, Cappuzzello, Del Prete, Dander, Biondi, DAmico: Mesenchymal stromal cell-secreted chemerin is a novel immunomodulatory molecule driving the migration of ChemR23-expressing cells. in Cytotherapy 2017 (PubMed)

More Antibodies against CCRL2 Interaction Partners

Human Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) interaction partners

  1. CCRL2 mRNA was not significantly changed in murine and human non-alcoholic steatohepatitis liver. CCRL2 mRNA levels were positively correlated with inflammation, fibrosis and NASH scores in the patients.

  2. CCRL2 inhibited the growth of breast cancer cells in vitro and in vivo.

  3. in breast cancer, CRAM-A becomes specifically upregulated under inflammatory stimuli and may serve as a potential marker of immune response.

  4. these results suggest for the first time that elevated CCRL2 in glioma promotes cell migration and invasion.

  5. Considering the newly defined role of CCRL2 in lung dendritic cell trafficking, this atypical chemokine receptor may affect pneumocystis pneumonia through immune regulation and inducing inflammation.

  6. demonstration that the homeostatic chemokine CCL19 is a specific ligand for CRAM

  7. CCRL2 expression is up-regulated on synovial neutrophils of rheumatoid arthritis patients

  8. Results identify chemerin as a natural nonsignaling protein ligand for both human and mouse CCRL2.

Mouse (Murine) Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) interaction partners

  1. Ccrl2 modulates chemerin levels in the epithelial lining fluid of the lungs but does not contribute to the development of O3-induced lung pathology.

  2. upregulation of CCRL2 observed under inflammatory conditions is functional to finely tune CXCR2-mediated neutrophil recruitment at sites of inflammation.

  3. chemokine (CC motif) receptor-like 2 should be considered to be a molecule involved in the regulation of the inflammatory response associated with multiple sclerosis.

  4. CCRL2 mRNA was not significantly changed in murine and human non-alcoholic steatohepatitis liver. CCRL2 was related to the mRNA levels of F4/80, transforming growth factor beta and alpha smooth muscle actin in murine non-alcoholic steatohepatitis.

  5. Proinflammatory stimuli upregulate atypical chemerin receptor CCRL2 and VCAM-1 on endothelial cells via NF-kappaB and JAK/STAT intracellular signaling pathways.

  6. Ccrl2(-/-) mice showed normal recruitment of circulating dendritic cells (DC) into the lung, but a defective trafficking of antigen-loaded lung DC to mediastinal lymph nodes.

  7. Expression of L-CCR mRNA is reported in murine astrocytes and microglia and is greatly enhanced under proinflammatory conditions; this receptor may play a role in neuroinflammatory processes.

  8. Prominent expression of L-CCR mRNA is detected in astrocytes and microglia at early time points throughout the brain and spinal cord in experimental autoimmune encephalomyelitis supporting the proposed relationship of L-CCR expression to CNS inflammation.

  9. Results identify chemerin as a natural nonsignaling protein ligand for both human and mouse CCRL2.

CCRL2 Antigen Profile

Protein Summary

This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.

Gene names and symbols associated with CCRL2

  • C-C motif chemokine receptor like 2 (Ccrl2) antibody
  • C-C motif chemokine receptor like 2 (CCRL2) antibody
  • chemokine (C-C motif) receptor-like 2 (Ccrl2) antibody
  • 1810047I05Rik antibody
  • Ackr5 antibody
  • CCR11 antibody
  • CCRL2 antibody
  • CKRX antibody
  • Cmkbr1l2 antibody
  • CRAM antibody
  • CRAM-A antibody
  • CRAM-B antibody
  • E01 antibody
  • HCR antibody
  • L-CCR antibody

Protein level used designations for CCRL2

C-C chemokine receptor-like 2 , chemokine (C-C motif) receptor-like 2 , c-C chemokine receptor-like 2-like , atypical chemokine receptor 5 , chemokine receptor CCR11 , chemokine receptor X , putative MCP-1 chemokine receptor , G-protein coupled beta chemokine receptor , chemokine (C-C) receptor 1,-like 2 , chemokine (C-C) receptor 1-like 2 , lipopolysaccharide inducible C-C chemokine receptor related , lipopolysaccharide-inducible C-C chemokine receptor , lipopolysacharide-inducible C-C chemokine receptor , chemokine C-C motif receptor-like 2

GENE ID SPECIES
316019 Rattus norvegicus
460324 Pan troglodytes
484788 Canis lupus familiaris
100439180 Pongo abelii
100582482 Nomascus leucogenys
9034 Homo sapiens
54199 Mus musculus
414370 Sus scrofa
515976 Bos taurus
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