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Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Additionally we are shipping CXCL16 Antibodies (181) and CXCL16 Proteins (49) and many more products for this protein.
Showing 10 out of 93 products:
Mouse (Murine) CXCL16 ELISA Kit for Sandwich ELISA - ABIN625119
Zeng, See, Phallen, Jackson, Belcaid, Ruzevick, Durham, Meyer, Harris, Albesiano, Pradilla, Ford, Wong, Hammers, Mathios, Tyler, Brem, Tran, Pardoll, Drake, Lim: Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. in International journal of radiation oncology, biology, physics 2013
Show all 6 Pubmed References
Mouse (Murine) CXCL16 ELISA Kit for Sandwich ELISA - ABIN2683996
Matloubian, David, Engel, Ryan, Cyster: A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. in Nature immunology 2001
Show all 3 Pubmed References
Inflammation accelerates renal tubulointerstitial lesions in mouse model of diabetic nephropathy by increasing the activity of CXCL16 pathway.
CXCL16 increases the frequency of the miniature excitatory synaptic currents (mEPSCs) and reduces the PPR (show PTH1R ELISA Kits) of evoked excitatory transmission, indicating that the chemokine (show CCL1 ELISA Kits) also modulates and enhances the release of glutamate (show GRIN1 ELISA Kits).
results indicate that CXCL16 plays a key role in the pathogenesis of renal injury and fibrosis in salt-sensitive hypertension through regulation of bone marrow-derived fibroblast accumulation and macrophage and T cell infiltration.
Data indicate that chemokine (show CCL1 ELISA Kits) C-X-C ligand 16 (CXCL16) is a critical regulator of liver immune response to acetaminophen (APAP)-induced hepatotoxicity, suggesting a potential strategy for the treatment of drug-induced acute liver failure by targeting CXCL16.
CXCL16 plays a crucial role in the pathogenesis of cisplatin-induced acute kidney injury through regulation of apoptosis and inflammation.
These findings suggest that the CXCL16 gene product promotes inflammatory factors and cell infiltration factors, and inhibits the expression of antioxidant factors to accelerate the development of DN, and CXCL16 deficiency attenuates DN may be involved in the AKT (show AKT1 ELISA Kits) signaling pathway.
Results indicate that CXCL16 plays a pivotal role in the pathogenesis of renal artery stenosis-induced renal injury and fibrosis through regulation of bone marrow-derived fibroblast accumulation and macrophage and T-cell infiltration.
Simvastatin exerts a protective effect on renal function and structure in mice with ADR nephropathy which related to the decreasing expression of CXCL16 in glomerular podocytes followed by the decreasing endocytosis of ox-LDL in podocytes and inhibition of NF-kappaB (show NFKB1 ELISA Kits) pathway activation.
These results indicate that MEK (show MDK ELISA Kits) inhibitor diminishes Nasopharyngeal carcinoma cell proliferation and NPC (show NPC1 ELISA Kits)-induced osteoclastogenesis via modulating CCL2 (show CCL2 ELISA Kits) and CXCL16 expressions.
Serum CXCL16 is increased in severe pancreatitis with infected pancreatic necrosis and identifies patients who benefit from surgical necrosectomy
activation of cancer-associated fibroblasts and expression of CXCL16, shown to be a monocyte chemoattractant.
Enhanced CXCL16 expression in lung cancer tissue promoted the proliferation and invasion of lung cancer cells. CXCL16 might promote proliferation and invasion of lung cancer by regulating the NF-kappaB (show NFKB1 ELISA Kits) pathway.
increased plasma sCXCL16 might be implicated in the pathogenesis of immune thrombocytopenia and have a relationship with Th1 (show TH1L ELISA Kits)/Th2 imbalance.
Serum CXCL16 levels are significantly increased in patients with gallstone, and are independently associated with liver injury in Chinese population, suggesting that CXCL16 may be a biomarker of liver injury in subjects with gallstone or NAFLD (show TSC2 ELISA Kits). Hepatic CXCL16 mRNA and protein levels were also significantly increased in gallstone patients
IFN-gamma (show IFNG ELISA Kits), CXCL16 and uPAR (show PLAUR ELISA Kits) are promising as effective biomarkers of disease activity, renal damage, and the activity of pathological lesions in systemic lupus erythematosus.
Data showed that reverse signaling via CXCL16 promotes migration in CXCL16-expressing melanoma and glioblastoma cells, but does not affect proliferation or protection from chemically-induced apoptosis.
Study showed, for the first time, highly significant relationships of circulating CXCL16 level with cardiac injury markers in dialysis patients.
Women with gestational diabetes mellitus and preeclampsia had a dysregulated CXC chemokine ligand 16 during pregnancy, and in gestational diabetes mellitus, the increase in CXC chemokine ligand 16 early in pregnancy and after 5 years was strongly associated with their lipid profile.
Data suggest that primary cells from papillary renal cell carcinoma secrete the chemokines IL8 (show IL8 ELISA Kits), CXCL16, and chemerin (show RARRES2 ELISA Kits); these chemokines attract primary human monocytes and induce shift/transdifferentiation in monocytes toward M2 macrophage/foam cell phenotype. (IL8 (show IL8 ELISA Kits) = interleukin-8 (show IL8 ELISA Kits); CXCL16 = C-X-C motif chemokine (show CCL1 ELISA Kits) ligand 16)
Our study demonstrated that CXCL16-CXCR6 (show CXCR6 ELISA Kits) mediates CD8 (show CD8A ELISA Kits)(+) T-cell skin trafficking under oxidative stress in patients with vitiligo (show MITF ELISA Kits), and CXCL16 expression in human keratinocytes induced by ROS (show ROS1 ELISA Kits) is, at least in part, caused by unfolded protein response activation
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
chemokine (C-X-C motif) ligand 16
, C-X-C motif chemokine 16
, Transmembrane chemokine CXCL16
, Cxc chemokine ligand 16
, scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
, small-inducible cytokine B16
, transmembrane chemokine CXCL16
, zinc finger, MYND-type containing 15
, CXC chemokine ligand 16