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Receptor for the C-X-C chemokine CXCL16. Additionally we are shipping CXCR6 Antibodies (256) and CXCR6 Kits (8) and many more products for this protein.
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In this study, we undertook a comprehensive comparison of CXCR6 gene variation in two South African populations (black and Caucasian) and investigated the possible association between two CXCR6 SNPs and different phenotypes of HIV-1 control in HIV-1-infected black South African individuals.
Our study demonstrated that CXCL16 (show CXCL16 Proteins)-CXCR6 mediates CD8 (show CD8A Proteins)(+) T-cell skin trafficking under oxidative stress in patients with vitiligo (show MITF Proteins).
the DRF (show MPO Proteins) motif of CXCR6 may display a receptor adaptation allowing adhesion and cell retention by transmembrane CXCL16 (show CXCL16 Proteins) but reducing the chemotactic response to soluble CXCL16 (show CXCL16 Proteins).
this study shows that CXCR6 mRNA levels in osteosarcoma tissues are higher than those in normal bone tissues
CXCR6 rs2234358 was associated with HCV spontaneous clearance and response to IFN-alpha/RBV therapy in Chinese Han population.
The expression level of CXCR6 was increased in gastric cancer.
The expression of CXCL16 (show CXCL16 Proteins) and and its receptor, CXCR6, their immunolocalization in disc tissue and their presence following exposure of cultured human annulus fibrosus cells to proinflammatory cytokines are reported.
Inflammation contributed to foam cell formation in the radial arteries of ESRD patients via activation of the CXCL16 (show CXCL16 Proteins)/CXCR6 pathway, which may be regulated by P2X7R (show P2RX7 Proteins).
High CXCR6 expression is associated with prostate cancer.
MiR (show MLXIP Proteins)-361-5p was down-regulated in Hepatocellular Carcinoma tissues in comparison to adjacent normal tissues, due to hypermethylation at its promoter region. Overexpression of miR (show MLXIP Proteins)-361-5p suppressed proliferation and invasion of HCC (show FAM126A Proteins) cells. Chemokine (C-X-C Motif) receptor 6 (CXCR6) was identified as a target of miR (show MLXIP Proteins)-361-5p.
these results demonstrate an important role of CXCR6 in the regulation of pathological Th17 and IL-17A (show IL17A Proteins)(+)TCRgammadelta(+) T-cell recruitment into atherosclerotic lesions.
CXCR6 has a role in the circulation of innate lymphoid cell precursors and their progeny
CXCR6 is essential for pressure overload-mediated myocardial recruitment of monocytes, which contributes to cardiac fibrosis through TNF-alpha (show TNF Proteins)-dependent MMP9 (show MMP9 Proteins) activation and collagen synthesis.
CXCR6 appears to influence long-term survival and tissue distribution of activated T cells.
CXCR6 deficiency inhibited total collagen deposition and suppressed the expression of collagen I and fibronectin (show FN1 Proteins) in obstructed kidneys.
Intestinal ILC3s expressed CXCR6 and its ablation generated a selective loss of the NKp46 (show NCR1 Proteins)(+) ILC3 subset, a depletion of intestinal IL-22 (show IL22 Proteins), and the inability to control C. rodentium infection.
CXCR6 plays important roles in the pathogenesis of arthritis through its effects on both T cell cytokine polarization and homing of T cells to inflamed joints.
critical for the development and maintenance of protective memory CD8 (show CD8A Proteins)+ T cells in the liver
CXCR6 plays a pivotal role in the development of Ang II (show AGT Proteins)-induced renal injury and fibrosis through regulation of macrophage and T-cell infiltration and bone marrow-derived fibroblast accumulation.
CXCR6, the receptor for CXCL16 (show CXCL16 Proteins), is critically involved in the pathogenesis of myocardial remodeling and development of heart failure following ischemia/reperfusion injury.
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
C-X-C chemokine receptor type 6
, chemokine C-X-C motif receptor 6
, G protein-coupled receptor TYMSTR
, chemokine (C-X-C motif) receptor 6
, G protein-coupled receptor
, G-protein coupled receptor STRL33
, G-protein coupled receptor bonzo
, chemokine receptor CXCR6
, G protein-coupled receptor STRL33
, chemokine receptor bonzo