CXCR6 Protein
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- Target See all CXCR6 Proteins
- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CXCR6 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product CXCR6 Protein
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Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) protein (GST tag)
CXCR6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) protein (Strep Tag)Crystallography grade CXCR6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-351) protein (Strep Tag)Crystallography grade CXCR6 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
- Alternative Name
- CXCR6 (CXCR6 Products)
- Synonyms
- BONZO Protein, CD186 Protein, STRL33 Protein, TYMSTR Protein, BB217514 Protein, C-X-C motif chemokine receptor 6 Protein, chemokine (C-X-C motif) receptor 6 L homeolog Protein, chemokine (C-X-C motif) receptor 6 Protein, CXCR6 Protein, cxcr6.L Protein, Cxcr6 Protein
- Background
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BONZO, CD186, CDw186, STRL33, TYMSTR
Description: The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020] - Molecular Weight
- The human full length CXCR6 protein has a MW of 39.3 kDa
- UniProt
- O00574
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