anti-Chibby Homolog 1 (Drosophila) (CBY1) Antibodies

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. Additionally we are shipping CBY1 Proteins (11) and CBY1 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CBY1 25776 Q9Y3M2
CBY1 73739 Q9D1C2
CBY1 246768 Q8K4I6
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Top anti-CBY1 Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of MDA-MB231 cells using CBY1 Antibody (C-term) Cat.-No AP52100PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human brain tissue reacted with CBY1 Antibody (C-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL 6 to 8 Days
$484.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of CBY1 expression in transfected 293T cell line by CBY1 MaxPab polyclonal antibody.Lane 1: CBY1 transfected lysate(13.86 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human kidney cancer labeled with CBY1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$317.90
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged CBY1 is approximately 0.1ng/ml as a capture antibody. Western Blot analysis of CBY1 expression in transfected 293T cell line by CBY1 monoclonal antibody (M06), clone 2F2.Lane 1: CBY1 transfected lysate (Predicted MW: 14.5 KDa).Lane 2: Non-transfected lysate. 100 μg 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.1 KDa) . 50 μL 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated WB Western Blot analysis of CBY1 expression in transfected 293T cell line by CBY1 MaxPab polyclonal antibody.Lane 1: CBY1 transfected lysate(14.50 KDa).Lane 2: Non-transfected lysate. 100 μg 11 to 12 Days
$425.71
Details
Human Rabbit Cy7 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy3 IF (p)   100 μL 14 to 21 Days
$416.90
Details

More Antibodies against CBY1 Interaction Partners

Xenopus laevis Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression.

Human Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. Our study reveals an association between Chibby expression and cancer aerobic glycolysis, which highlights the importance of Wnt/beta-catenin pathway in regulation of energy metabolism of NPC. These results indicate that Chibby and PDK1 are the potential target for NPC treatment.

  2. FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes.

  3. chronic Cby1 knockdown in colon cancer cells may counteract tumor progression by promoting the mesenchymal-to-epithelial transition process.

  4. Cby's C-terminal domain alone binds to TC-1 with significantly greater affinity compared to full-length Cby, implying that target binding of the coiled-coil domain is affected by the flanking disordered regions.

  5. CBY1 downregulation in CML comes from reduced protein stability when bound to 14-3-3sigma adapter protein. Dissociation raises CBY1 protein levels by enhancing its stability. The ubiquitin proteasome system reduces 14-3-3sigma-bound CBY1 stability by SUMOylation.

  6. Results show the hypermethylation of CBY1 and BCL2-like11 promoters proceeding from DNMT1 is a crucial component of their reduced expression, but it is not directly involved in chronic myeloid leukemia resistance to imatinib.

  7. Study showed that expression of Cby protein was strongly downregulated in laryngeal squamous cell carcinoma (LSCC) tumor tissues in comparison to normal laryngeal mucosa samples.

  8. the impact of BCR-ABL1 on Chibby1, a beta catenin antagonist involved in cell differentiation and transformation

  9. Stable expression of CBY1 drives beta catenin cytoplasmatic translocation and impairs beta catenin signaling in BCR-ABL + cells.

  10. Results from the association analysis suggest that common variation in CBY is not a cause for obesity in the Belgian population.

  11. C-terminal polycystin-2 influences the interaction with PIGEA14

  12. Cby plays an important role in organization of both primary and motile cilia in collaboration with Cnx.

  13. The N-terminal portion of the CBY1 is unstructured in solution, but the C-terminal half forms a coiled-coil structure.

  14. Chibby and clusterin were co-immunoprecipitated with NBPF1.

  15. These findings unravel the molecular basis through which a combinatorial action of Cby and 14-3-3 proteins controls the dynamic nuclear-cytoplasmic trafficking of beta-catenin.

  16. Chibby inhibits beta-catenin-mediated transcriptional activation by competing with Lef-1 to bind to beta-catenin

  17. PIGEA-14 plays an important role in regulating the intracellular location of polycystin-2

  18. As no somatic mutation was detected in C22orf2 in 36 colorectal tumour DNA, our results do not support the implication of Chibby as a tumour suppressor in colorectal carcinogenesis.

  19. Chibby is not likely to promote colorectal carcinoma tumor development or progression.

  20. CBY promotes adipocyte differentiation through inhibition of beta catenin signaling.

Mouse (Murine) Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes.

  2. Cby1 is required for efficient recruitment of Ahi1, providing a possible molecular mechanism for the ciliogenesis defect in Cby1(-/-) cells.

CBY1 Antigen Profile

Protein Summary

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CBY1

  • chibby homolog 1 S homeolog (cby1.S) antibody
  • chibby homolog 1 (cby1) antibody
  • chibby family member 1, beta catenin antagonist (CBY1) antibody
  • chibby family member 1, beta catenin antagonist (Cby1) antibody
  • 1110014P06Rik antibody
  • arb1 antibody
  • C22orf2 antibody
  • CBY antibody
  • chibby antibody
  • HS508I15A antibody
  • Pgea1 antibody
  • PGEA14 antibody
  • PIGEA-14 antibody
  • PIGEA14 antibody

Protein level used designations for CBY1

chibby homolog 1 , leucine-rich protein , ARPP-binding protein , PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 , PKD2 interactor, golgi and endoplasmic reticulum associated 1 , coiled-coil protein PIGEA-14 , cytosolic leucine-rich protein , polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa , protein chibby homolog 1 , PIGEA-14

GENE ID SPECIES
398327 Xenopus laevis
549007 Xenopus (Silurana) tropicalis
25776 Homo sapiens
73739 Mus musculus
246768 Rattus norvegicus
282859 Bos taurus
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