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CHN2 is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. Additionally we are shipping Chimerin (Chimaerin) 2 Proteins (9) and many more products for this protein.
Showing 10 out of 65 products:
Human Polyclonal CHN2 Primary Antibody for IHC (p), IHC - ABIN451800
Siliceo, Mérida: T cell receptor-dependent tyrosine phosphorylation of beta2-chimaerin modulates its Rac-GAP function in T cells. in The Journal of biological chemistry 2009
Human Polyclonal CHN2 Primary Antibody for ICC, IF - ABIN4297936
Alvi, McArt, Kelly, Fuchs, Alderdice, McCabe, Bingham, McGready, Tripathi, Emmert-Streib, Loughrey, McQuaid, Maxwell, Hamilton, Turkington, James, Wilson, Salto-Tellez: Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility. in Oncotarget 2015
This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
, chimerin (chimaerin) 2
, Rho GTPase-activating protein 3
, beta chimaerin
, chimaerin 2
, rho-GTPase-activating protein 3
, rho GTPase-activating protein 3