anti-Chloride Channel 3 (CLCN3) Antibodies

CLCN3 encodes a member of the voltage-gated chloride channel (ClC) family. Additionally we are shipping Chloride Channel 3 Proteins (7) and Chloride Channel 3 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLCN3 1182 P51790
CLCN3 84360 P51792
CLCN3 12725 P51791
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Top anti-Chloride Channel 3 Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-CLCN3 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Bat Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated WB CLCN3 Antibody (Center)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CLCN3 antibody detected the CLCN3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse HRP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Clcn3 Monoclonal Antibody, Clone S258-5 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Clcn3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane, Endosome, Endosome membrane, Cytoplasmic Vesicle, Secretory Vesicle Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Clcn3 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~90 kDa CIcn3 protein using Mouse Anti-CIcn3 Monoclonal Antibody, Clone S258-5 . Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-CIcn3 Monoclonal Antibody  at 1:200 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~90 kDa. 100 μg Log in to see 2 to 3 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Clcn3 Monoclonal Antibody, Clone S258-5 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Clcn3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane, Endosome, Endosome membrane, Cytoplasmic Vesicle, Secretory Vesicle Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Clcn3 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~90 kDa CIcn3 protein using Mouse Anti-CIcn3 Monoclonal Antibody, Clone S258-5 . Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-CIcn3 Monoclonal Antibody  at 1:200 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~90 kDa. 100 μg Log in to see 2 to 3 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Clcn3 Monoclonal Antibody, Clone S258-5 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Clcn3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane, Endosome, Endosome membrane, Cytoplasmic Vesicle, Secretory Vesicle Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Clcn3 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~90 kDa CIcn3 protein using Mouse Anti-CIcn3 Monoclonal Antibody, Clone S258-5 . Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-CIcn3 Monoclonal Antibody  at 1:200 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~90 kDa. 100 μg Log in to see 2 to 3 Days
$429.00
Details
Human Mouse Biotin ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Clcn3 Monoclonal Antibody, Clone S258-5 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Clcn3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane, Endosome, Endosome membrane, Cytoplasmic Vesicle, Secretory Vesicle Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Clcn3 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~90 kDa CIcn3 protein using Mouse Anti-CIcn3 Monoclonal Antibody, Clone S258-5 . Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-CIcn3 Monoclonal Antibody  at 1:200 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~90 kDa. 100 μg Log in to see 2 to 3 Days
$431.20
Details
Human Mouse PE ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Clcn3 Monoclonal Antibody, Clone S258-5 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Clcn3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane, Endosome, Endosome membrane, Cytoplasmic Vesicle, Secretory Vesicle Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Clcn3 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~90 kDa CIcn3 protein using Mouse Anti-CIcn3 Monoclonal Antibody, Clone S258-5 . Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-CIcn3 Monoclonal Antibody  at 1:200 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~90 kDa. 100 μg Log in to see 2 to 3 Days
$432.30
Details
Human Mouse Streptavidin ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Clcn3 Monoclonal Antibody, Clone S258-5 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Clcn3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane, Endosome, Endosome membrane, Cytoplasmic Vesicle, Secretory Vesicle Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Clcn3 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~90 kDa CIcn3 protein using Mouse Anti-CIcn3 Monoclonal Antibody, Clone S258-5 . Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-CIcn3 Monoclonal Antibody  at 1:200 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~90 kDa. 100 μg Log in to see 2 to 3 Days
$433.40
Details
Human Mouse PerCP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Clcn3 Monoclonal Antibody, Clone S258-5 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Clcn3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane, Endosome, Endosome membrane, Cytoplasmic Vesicle, Secretory Vesicle Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Clcn3 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~90 kDa CIcn3 protein using Mouse Anti-CIcn3 Monoclonal Antibody, Clone S258-5 . Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-CIcn3 Monoclonal Antibody  at 1:200 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~90 kDa. 100 μg Log in to see 2 to 3 Days
$434.50
Details

CLCN3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Chloride Channel 3 Antibodies

  1. Mammalian Monoclonal CLCN3 Primary Antibody for WB - ABIN1304600 : Gaurav, Bewtra, Agrawal: Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics. in Immunity, inflammation and disease 2015 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal CLCN3 Primary Antibody for IHC, WB - ABIN2776327 : Salazar, Love, Styers, Werner, Peden, Rodriguez, Gearing, Wainer, Faundez: AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 Pubmed References

  3. Rat (Rattus) Polyclonal CLCN3 Primary Antibody for WB - ABIN1742509 : Eckenstaler, Lessmann, Brigadski: CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons. in Journal of cell science 2016 (PubMed)

  4. Human Polyclonal CLCN3 Primary Antibody for IF (p), IHC (p) - ABIN1386131 : Larrouture, Nelson, Robinson, Liu, Tourkova, Schlesinger, Blair: Chloride-hydrogen antiporters ClC-3 and ClC-5 drive osteoblast mineralization and regulate fine-structure bone patterning in vitro. in Physiological reports 2015 (PubMed)

More Antibodies against Chloride Channel 3 Interaction Partners

Human Chloride Channel 3 (CLCN3) interaction partners

  1. ClC-3 is a potential target of 17beta-estradiol and is modulated by the ERalpha (show ESR1 Antibodies) in breast cancer cells.

  2. SDPR (show SDPR Antibodies) variants were not associated with major depressive disorder.

  3. Overall, these data suggest that Cavin-2 (show SDPR Antibodies) represents a useful marker for discriminating the degree of differentiation in LPS (show IRF6 Antibodies) tumors.

  4. Study provided novel and compelling evidence for the functional role of the unique CLC-3, which are significantly upregulated during ischemia, in the protection of the heart under stress

  5. Data found that CVN2 expression was signi fi cantly down-regulated in oral squamous cell carcinoma (OSCC) in vitro and in vivo and that CVN2 overexpression led to decreased proliferative activities through the CVN2/caveolin-1 (show CAV1 Antibodies)/ERK (show EPHB2 Antibodies) path- way. Furthermore, high tumoral progression occurred in CVN2-negative patients with OSCC.

  6. Hepatocellular carcinoma patients with lower cavin-2 (show SDPR Antibodies) expression have a relatively poor prognosis.

  7. ClC-3 promotes endometriotic cell migration and invasion.

  8. identification of a novel metastasis suppressor gene, serum deprivation response (SDPR (show SDPR Antibodies)), localized to 2q32-33, a region reported to be associated with significant loss of heterozygosity in breast cancer, is reported.

  9. Cavin-1 (show PTRF Antibodies) and cavin-2 (show SDPR Antibodies) are strongly expressed within caveolae-like structures within liver sinusoidal endothelial cells of the hepatitis C-related cirrhotic liver and cavin-1 (show PTRF Antibodies) would play a critical role in regulating aspects of caveolin-1 (show CAV1 Antibodies).

  10. these results demonstrated that ClC-3 is involved in the proliferation and migration of osteosarcoma cell

Mouse (Murine) Chloride Channel 3 (CLCN3) interaction partners

  1. Results have shown that the expression of ClC-3 was reduced in hypertrophic H9c2 cells, primary rat neonatal cardiomyocytes and myocardium of C57/BL/6 mice and that ClC-3 played an important role in beta-adrenergic cardiac hypertrophy.

  2. we conclude that the expression of ClC-3 chloride channels in osteoblasts helps them respond to PTH (show PTH Antibodies) stimulation, which mediates osteogenic differentiation.

  3. our findings show that Cl(-) channels can be activated by estrogen via ERa on the cell membrane and suggest that the ClC-3 Cl(-) channel may be one of the targets of estrogen in the regulation of osteoblast activity.

  4. ClC-3 is an endogenous inhibitor of neuropathic pain development and down-regulation of ClC-3 contributes to mechanical hypersensitivity.

  5. This study provides a new mechanism by which endophilin A2 (show SH3GL1 Antibodies) regulates ClC-3 channel activity, and sheds light on how ClC-3 is transported to cell membranes to play its critical role as a chloride channel (show CLCA1 Antibodies) in VSMCs function

  6. roles of AQP-3 (show AQP3 Antibodies) in AQP-3 (show AQP3 Antibodies) aquaglyceroporin and ClC-3 chloride channels complex

  7. ClC-3 plays a major role in hyperglycemia induced hippocampal neuronal apoptosis.

  8. Threonine532 phosphorylation in ClC-3 channels is required for angiotensin II-induced Cl(-) current and migration in cultured vascular smooth muscle cells

  9. Data suggest that ClC3/Clcn3 expression is up-regulated by mechanical stimulation (persistent static compression here) in osteoblastic cell line and appears to participate in mechanically sensitive osteogenesis and gene expression regulation.

  10. Our findings demonstrated that ClC-3 deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK (show MAPK8 Antibodies)/p38 MAPK (show MAPK14 Antibodies) dependent SR-A (show MSR1 Antibodies) expression and foam cell formation.

Guinea Pig Chloride Channel 3 (CLCN3) interaction partners

  1. ClC-3 is specialized in mainly performing incomplete capacitive nontransporting cycles in intracellular membranes.

Xenopus laevis Chloride Channel 3 (CLCN3) interaction partners

  1. A local enhancement of CIC (show CIC Antibodies)-3 expression at the leading edge of the wounded epidermis was found to be specific to closing wounds.

Chloride Channel 3 (CLCN3) Antigen Profile

Protein Summary

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.

Gene names and symbols associated with CLCN3

  • chloride voltage-gated channel 3 (CLCN3) antibody
  • chloride voltage-gated channel 3 (Clcn3) antibody
  • chloride channel, voltage-sensitive 3 (Clcn3) antibody
  • chloride channel 3 (clcn3) antibody
  • H(+)/Cl(-) exchange transporter 5 (LOC5572287) antibody
  • chloride channel protein 3 (PTRG_03131) antibody
  • chloride channel protein 3 (BDBG_05668) antibody
  • chloride channel protein 3 (MCYG_04420) antibody
  • chloride channel, voltage-sensitive 3 (clcn3) antibody
  • caveolae associated protein 2 (CAVIN2) antibody
  • chloride channel, voltage-sensitive 3 S homeolog (clcn3.S) antibody
  • cavin-2 antibody
  • CAVIN2 antibody
  • clc-3 antibody
  • clc3 antibody
  • CLCN3 antibody
  • fb78c02 antibody
  • PS-p68 antibody
  • SDR antibody
  • wu:fb78c02 antibody

Protein level used designations for CLCN3

H(+)/Cl(-) exchange transporter 3 , chloride channel 3 , chloride channel protein 3 , chloride transporter ClC-3 , protein kinase C-regulated chloride channel , clC-3 , chloride channel Clc-3 , Chloride channel protein 3 , H(+)/Cl(-) exchange transporter 3-like , phosphatidylserine binding protein , phosphatidylserine-binding protein , serum deprivation-response protein , putative chloride channel ClC-3

GENE ID SPECIES
1182 Homo sapiens
84360 Rattus norvegicus
12725 Mus musculus
422432 Gallus gallus
471346 Pan troglodytes
477354 Canis lupus familiaris
522719 Bos taurus
559340 Danio rerio
5572287 Aedes aegypti
6341356 Pyrenophora tritici-repentis Pt-1C-BFP
8503901 Ajellomyces dermatitidis SLH14081
9229794 Arthroderma otae CBS 113480
100008673 Oryctolagus cuniculus
100021050 Monodelphis domestica
100061225 Equus caballus
100074971 Ornithorhynchus anatinus
100135501 Cavia porcellus
100156049 Sus scrofa
100174300 Pongo abelii
100216107 Xenopus (Silurana) tropicalis
100380301 Salmo salar
100404608 Callithrix jacchus
100581879 Nomascus leucogenys
8436 Homo sapiens
399089 Xenopus laevis
Selected quality suppliers for anti-Chloride Channel 3 (CLCN3) Antibodies
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