anti-Chloride Channel Accessory 2 (CLCA2) Antibodies

The protein encoded by CLCA2 belongs to the calcium sensitive chloride conductance protein family. Additionally we are shipping CLCA2 Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLCA2 9635 Q9UQC9
CLCA2 362052  
CLCA2 229933 Q8BG22
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Top anti-CLCA2 Antibodies at antibodies-online.com

Showing 7 out of 15 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CLCA2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: CLCA2 Antibody [NBP2-33482] - glioma Western Blot: CLCA2 Antibody [NBP2-33482] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB Western Blot: CLCA2 Antibody [NBP1-80071] - THP-1 cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$488.73
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.85 KDa) . 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.22 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μg Log in to see 13 to 16 Days
$380.00
Details
Human Rabbit Un-conjugated ELISA, WB   150 μL Log in to see 13 to 16 Days
$753.50
Details

More Antibodies against CLCA2 Interaction Partners

Human Chloride Channel Accessory 2 (CLCA2) interaction partners

  1. CLCA2 suppress NPC proliferation, migration, invasion and epithelial-mesenchymal transition through inhibiting FAK/ERK signaling.

  2. identified a new molecular mechanism to explain PCa and MeS link based on CLCA2 repression by CTBP1 and miR-196b-5p molecules that might act as key factors in the progression onset of this disease

  3. we found by calcium imaging that CLCA2 moderately enhanced intracellular-store release but dramatically increased store-operated entry of calcium upon cytosolic depletion

  4. CLCA2 links junctional adhesion molecule EVA1, to cytosolic signaling proteins that modulate proliferation and differentiation.

  5. CLCA2 expression is higher in squamous cell carcinoma of the lung compared with adenocarcinoma.

  6. Variants in CLCA2 were associated with an ileal involvement phenotype of Crohn's disease.

  7. These results strongly suggest that CLCA2 is involved in the p53 tumor suppressor network and has a significant effect on cell migration and invasion.

  8. hCLCA2 is required for epithelial differentiation, and its loss during tumor progression contributes to metastasis.

  9. the reduced expression of CLCA2 was frequently observed in various kinds of cancers including prostate cancer

  10. Expression of hSK4 as well as hCACC-2 and hCACC-3 but not hCACC-1 was demonstrated by reverse transcriptase PCR on native nasal tissues.

  11. immunohistochemistry clearly demonstrated colocalisation between hCLCA2 and integrin beta4

  12. human CLCA2 protein and mRNA expression are elevated during epithelial stratification, suggesting that this protein plays a role in the growth of multi-layered corneal epithelia during both natural development and tissue cultivation.

  13. Mostly extracellular with only a single transmembrane segment, unlikely to form a channel.

  14. hCLCA2 Is a p53-Inducible Inhibitor of Breast Cancer Cell Proliferation.

Mouse (Murine) Chloride Channel Accessory 2 (CLCA2) interaction partners

  1. Stat3-mediated regulation of expression of members of the calcium-activated chloride channel regulator (CLCA) family of proteins during involution and mammary carcinogenesis.

  2. basal NF-kappaB activity is involved in the Ca(2+)-dependent regulation of mCLCA2 expression in a mouse keratinocyte line

  3. The results imply that mCLCA5 may play a role in maturation and keratinization of squamous epithelial cells.

  4. results establish mCLCA5 as the mouse ortholog of hCLCA2, demonstrate that mCLCA5 is a detachment-sensitive growth inhibitor, and suggest a mechanism whereby these channels may antagonize mammary tumor progression, metastases [CLCA5]

CLCA2 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.

Gene names and symbols associated with CLCA2

  • chloride channel accessory 2 (CLCA2) antibody
  • calcium-activated chloride channel regulator 2 (LOC100081268) antibody
  • chloride channel calcium activated 2 (Clca2) antibody
  • chloride channel accessory 2 (Clca2) antibody
  • 4732440A06 antibody
  • AI586120 antibody
  • CACC antibody
  • CaCC-3 antibody
  • CACC3 antibody
  • CLCA antibody
  • Clca2 antibody
  • Clca4 antibody
  • CLCRG2 antibody
  • rbCLCA antibody

Protein level used designations for CLCA2

CLCA family member 2, chloride channel regulator , calcium-activated chloride channel family member 2 , calcium-activated chloride channel protein 3 , calcium-activated chloride channel regulator 2 , calcium-activated chloride channel-2 , chloride channel regulator 2 , chloride channel, calcium activated, family member 2 , hCLCA2 , hCaCC-3 , chloride channel accessory 2 , calcium-activated chloride channel regulator 2-like , chloride channel calcium activated 2 , calcium activated chloride channel , chloride channel calcium activated 4 , Ca(2+)-activated chloride channel splicing , calcium-activated chloride channel family member 5 , mCLCA5

GENE ID SPECIES
9635 Homo sapiens
534256 Bos taurus
711959 Macaca mulatta
100339003 Oryctolagus cuniculus
100385716 Callithrix jacchus
100471268 Ailuropoda melanoleuca
100511753 Sus scrofa
100081268 Ornithorhynchus anatinus
362052 Rattus norvegicus
229933 Mus musculus
100052615 Equus caballus
612510 Canis lupus familiaris
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