Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) ELISA Kits

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Additionally we are shipping CHRNA2 Antibodies (41) and CHRNA2 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CHRNA2 170945 P12389
CHRNA2 110902 Q91X60
CHRNA2 1135 Q15822
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Top CHRNA2 ELISA Kits at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.625 ng/mL - 40 ng/mL   96 Tests Log in to see 11 to 18 Days
$589.86
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Rat
  96 Tests Log in to see 15 to 18 Days
$875.60
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Mouse
  96 Tests Log in to see 15 to 18 Days
$875.60
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Chicken
  96 Tests Log in to see 15 to 18 Days
$1,095.60
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More ELISA Kits for CHRNA2 Interaction Partners

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) interaction partners

  1. The results of this study demonstrated that alpha2* nAChRs influenced hippocampus-dependent learning and memory, as well as nicotine-facilitated CA1 (show CA1 ELISA Kits) hippocampal synaptic plasticity.

  2. Chrna2-expressing Martinotti cells selectively target L5 thick-tufted type A pyramidal cells (PCs) but not thin-tufted type B PCs.

  3. Study described Chrna2 expression in the amygdala and propose that this expression is a marker of the medial subpallium-derived amygdala

  4. The results of this study suggested that loss of the mouse nAChR (show CHRNA4 ELISA Kits) alpha2 subunit has very limited effects on baseline behavior but does lead to the potentiation of several nicotine-modulated behaviors.

Human Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) interaction partners

  1. A crystal structure of a human neuronal CHRNA2 extracellular domain in pentameric assembly has been reported.

  2. The rare variants in CHRNA2 were significantly associated with smoking status.

  3. a heterozygous single-nucleotide substitution in CHRNA2 gene (c.1126 C>T; p. Arg376Trp) in subjects with benign familial infantile seizures

  4. CHRNA2 mutations play a causative role in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE).

  5. Results show that D478E variation in nAChR (show CHRNA4 ELISA Kits) alpha2 subunit increases the peak current responses of both alpha2beta2- and alpha2beta4-nAChRs; but the D478N variation in nAChR (show CHRNA4 ELISA Kits) alpha2 subunit only increases the peak current responses of alpha2beta2-nAChRs

  6. Level of cigarettes per day during adolescence and young adulthood is associated with CHRNB3A6, CHRNA5A3B4, and CHRNA2

  7. Results indicate that the CHRNA2 signal peptide mutation T22I modulates the function of both alpha2beta2- and alpha2beta4-nAChR (show CHRNA4 ELISA Kits) and decreases sensitivities to nicotine and acetylcholine, and quite possibly increasing susceptibility to nicotine dependence

  8. findings indicate that both CHRNA2 and CHRNA6 play a significant role in the etiology of ND in AA and EA smokers

  9. mutations of CHRNB2 (show CHRNB2 ELISA Kits) and CHRNA2 genes may be rare in Chinese autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) population.

  10. A new CHRNA2 mutation markedly increases the receptor sensitivity to acetylcholine, indicating that the nicotinic alpha 2 subunit alteration is the underlying cause.

CHRNA2 Antigen Profile

Antigen Summary

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.

Gene names and symbols associated with CHRNA2

  • cholinergic receptor nicotinic alpha 2 subunit (CHRNA2) antibody
  • cholinergic receptor, nicotinic, alpha 2a (neuronal) (chrna2a) antibody
  • cholinergic receptor nicotinic alpha 2 subunit (Chrna2) antibody
  • cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) (Chrna2) antibody
  • neuronal acetylcholine receptor subunit alpha-2 (CpipJ_CPIJ002436) antibody
  • neuronal acetylcholine receptor subunit alpha-4-like (LOC100370261) antibody
  • neuronal acetylcholine receptor subunit alpha-2 (Tsp_10995) antibody
  • ACHR antibody
  • Acra-2 antibody
  • Acra2 antibody
  • BC011490 antibody
  • chrna2 antibody
  • NACHRA2 antibody
  • zgc:136717 antibody

Protein level used designations for CHRNA2

cholinergic receptor, nicotinic, alpha 2 (neuronal) , alpha-2 subunit, nicotinic acetylcholine receptor , cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) , neuronal acetylcholine receptor subunit alpha-2 , cholinergic receptor, nicotinic, alpha polypeptide 2a , nicotinic acetylcholine receptor , neuronal acetylcholine receptor subunit alpha-2-like , acetylcholine receptor, nicotinic, alpha 2 (neuronal)

GENE ID SPECIES
486101 Canis lupus familiaris
395607 Gallus gallus
712868 Macaca mulatta
678575 Danio rerio
170945 Rattus norvegicus
110902 Mus musculus
6033618 Culex quinquefasciatus
100370261 Saccoglossus kowalevskii
100403598 Callithrix jacchus
100451356 Pongo abelii
10903459 Trichinella spiralis
1135 Homo sapiens
472725 Pan troglodytes
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