Protein Summary

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.

Gene names and symbols associated with CHRNA2

• cholinergic receptor nicotinic alpha 2 subunit (CHRNA2) antibody
• cholinergic receptor, nicotinic, alpha 2a (neuronal) (chrna2a) antibody
• cholinergic receptor nicotinic alpha 2 subunit (Chrna2) antibody
• cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) (Chrna2) antibody
• neuronal acetylcholine receptor subunit alpha-2 (CpipJ_CPIJ002436) antibody
• Show all gene names
• neuronal acetylcholine receptor subunit alpha-4-like (LOC100370261) antibody
• neuronal acetylcholine receptor subunit alpha-2 (Tsp_10995) antibody

• ACHR antibody
• Acra-2 antibody
• Acra2 antibody
• BC011490 antibody
• chrna2 antibody
• Show all synonym aliases
• NACHRA2 antibody
• zgc:136717 antibody

Protein level used designations for CHRNA2

cholinergic receptor, nicotinic, alpha 2 (neuronal) , alpha-2 subunit, nicotinic acetylcholine receptor , cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) , neuronal acetylcholine receptor subunit alpha-2 , cholinergic receptor, nicotinic, alpha polypeptide 2a , nicotinic acetylcholine receptor , neuronal acetylcholine receptor subunit alpha-2-like , acetylcholine receptor, nicotinic, alpha 2 (neuronal)