Coagulation Factor V Proteins (F5)

F5 encodes an essential cofactor of the blood coagulation cascade. Additionally we are shipping Coagulation Factor V Antibodies (132) and Coagulation Factor V Kits (67) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
F5 14067 O88783
F5 2153 P12259
F5 304929  
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Top Coagulation Factor V Proteins at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$720.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$742.00
Details
Escherichia coli (E. coli) Cow His tag,GST tag 100 μg Log in to see 15 to 18 Days
$781.00
Details
Escherichia coli (E. coli) Wild boar His tag 100 μg Log in to see 15 to 18 Days
$448.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$331.20
Details
Escherichia coli (E. coli) Pig Un-conjugated SDS-PAGE analysis of Pig Coagulation Factor V Protein. 100 μg Log in to see 11 to 18 Days
$469.04
Details
Human Human Un-conjugated   0.05 mg Log in to see 2 to 3 Days
$429.00
Details
Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
Details

F5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , ,
,
Rat (Rattus)

More Proteins for Coagulation Factor V (F5) Interaction Partners

Mouse (Murine) Coagulation Factor V (F5) interaction partners

  1. Mice with the FVL mutation do not have increased spermatogenesis as compared to wildtype mice.

  2. Platelet-derived FV contributes to the control of angiogenesis and is likely associated with thrombin (show F2 Proteins) generation in hind limb ischemia model.

  3. These findings reveal a novel biological function and mechanism of the protein C (show PROC Proteins) pathway in which protein S and the aPC (show APC Proteins)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (show APC Proteins) in the context of endotoxemia and infection

  4. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of alpha1-antitrypsin.

  5. The FVL mutation does not influence coagulation activation, lung inflammation or survival in lethal influenza A.

  6. It suggested that there could be a combination of GLA (show GLA Proteins) deficiency and FVL or other thrombosis-related gene defect in patients with genetic severe early-onset thrombosis.

  7. Data suggest that tissue factor (show F3 Proteins) and factor V induction by LPS (show TLR4 Proteins) may in part accelerate mesangioproliferative glomerulonephritis through activation of factor X and downstream proinflammatory and procoagulant mechanisms.

  8. The source of the FVL leading to accelerated thrombosis appears to be circulating, non-platelet-derived plasma FVL.

  9. FVL has the ability to improve the hemophilia A or B phenotype, but this effect is principally evident at the microcirculation level following a particular vascular injury.

  10. observations demonstrate a synergistic interaction between alpha-galactosidase A (show GLA Proteins) deficiency and Factor V Leiden toward tissue fibrin deposition; concomitant mutations in these genes may increase the penetrance of vascular thrombotic events in humans

Human Coagulation Factor V (F5) interaction partners

  1. factor V Leiden and MTHFR C677T polymorphisms were significantly associated with recurrent pregnancy loss (RPL) in Bosnian women...

  2. the prothrombotic activity of FII is the result of a polymorphism and of a missense mutation, whereas that of FV derives only from a polymorphism. The observation that a clotting factor (show F7 Proteins) defect may be associated with both bleeding or venous thrombosis depending on the site of the mutation has caused an extensive reevaluation of the blood clotting mechanism.

  3. study found the FVL A allele frequency and GA genotype are significantly more prevalent among patients with coronary artery disease (CAD) compared to controls and may be predisposing to CAD; further found that the FVL mutation is an independent risk factor whose effect is not modified by other risk factors; FV HR2 variation does not show any statistically significant association with CAD

  4. suggesting that the FVL paradox is related to the carriership of one wild type and one mutated factor V allele

  5. Review/Meta-analysis: Factor V G1691A single nucleotide gene polymorphism was associated with risk of ischemic stroke mainly in young adults.

  6. Factor V Leiden mutation is associated with venous thromboembolism in cancer.

  7. we were not able to confirm the association between the polymorphisms of f5, f2, and mthfr (show MTHFR Proteins) and pregnancy loss in Bosnian women

  8. Human FVL carriers have a higher total sperm count than non-carriers, with an adjusted mean difference of 31 x 106 (95%CI 0.2-61.7; P = 0.048).

  9. contribution of FVLeiden causing resistance to activated protein C in Indian population is not as strong as previously reported in Western countries

  10. The frequencies of GA and AA genotypes and A allele of coagulation factor V (FV) 1691G>A polymorphism significantly increased in the lower extremity deep venous thrombosis (LDVT) group. Patients with LDVT carrying A allele (GA + AA) had both higher patency and recurrence rates than those carrying GG genotype. Coagulation factor V (FV) 1691G>A polymorphism may be associated with both the risk and prognosis of LDVT.

Cow (Bovine) Coagulation Factor V (F5) interaction partners

  1. Data suggest factor Xa (FXa (show F10 Proteins)) and factor Va (FVa) compete to bind FXa (show F10 Proteins) on both PS model membranes and microparticles from activated platelets; this competition between dimerization/prothrombinase (show FGL2 Proteins) complex formation appears to regulate blood coagulation.

Coagulation Factor V (F5) Protein Profile

Protein Summary

This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.

Gene names and symbols associated with Coagulation Factor V Proteins (F5)

  • coagulation factor V (f5)
  • coagulation factor V (F5)
  • Ac2-120 protein
  • AI173222 protein
  • Cf-5 protein
  • Cf5 protein
  • FVL protein
  • PCCF protein
  • RPRGL1 protein
  • THPH2 protein

Protein level used designations for Coagulation Factor V Proteins (F5)

coagulation factor V , activated protein C cofactor , activated protein c cofactor , coagulation factor V jinjiang A2 domain , factor V Leiden , proaccelerin, labile factor

GENE ID SPECIES
100534566 Oreochromis niloticus
14067 Mus musculus
2153 Homo sapiens
304929 Rattus norvegicus
280687 Bos taurus
100715882 Cavia porcellus
397217 Sus scrofa
100685858 Canis lupus familiaris
101123649 Ovis aries
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