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CCDC8 encodes a coiled-coil domain-containing protein. Additionally we are shipping Coiled-Coil Domain Containing 8 Kits (12) and Coiled-Coil Domain Containing 8 Proteins (3) and many more products for this protein.
Showing 10 out of 45 products:
Human Polyclonal CCDC8 Primary Antibody for IP, WB - ABIN4288660
Dai, Tang, Jung, Qin, Aaronson, Gu: Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90. in Proceedings of the National Academy of Sciences of the United States of America 2011
Show all 2 Pubmed References
Human Polyclonal CCDC8 Primary Antibody for WB - ABIN949718
Hanson, Murray, OSullivan, Urquhart, Daly, Bhaskar, Biesecker, Skae, Smith, Cole, Kirk, Chandler, Kingston, Donnai, Clayton, Black: Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth. in American journal of human genetics 2011
Human Polyclonal CCDC8 Primary Antibody for ICC, IF - ABIN4288662
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Variants near TTN (show TTN Antibodies) and CCDC8 were associated with KI67 (show MKI67 Antibodies) expression, and rs2288563 and rs2562832 in TTN (show TTN Antibodies) are potential biomarkers for the prediction of clinical outcomes in hepatitis B-related hepatocellular carcinoma patients.
CCDC8 may suppress the invasion and metastasis of non-small cell lung cancer cells.
CUL7 (show CUL7 Antibodies), OBSL1 (show OBSL1 Antibodies) and CCDC8 modulate the alternative splicing of the INSR (show INSR Antibodies)
The CUL7 (show CUL7 Antibodies), OBSL1 (show OBSL1 Antibodies), and CCDC8 proteins form a 3M complex that functions in maintaining microtubule and genome integrity and normal development.
Mutations in CUL7 (show CUL7 Antibodies), OBSL1 (show OBSL1 Antibodies) and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.
discussion of roles of CCDC8, CUL7 (cullin 7 (show CUL7 Antibodies)), and OBSL1 (obscurin-like 1 (show OBSL1 Antibodies)) in growth and development using findings from patients with Miller-McKusick-Malvaux syndrome and Silver-Russell syndrome [REVIEW]
p90 (show CANX Antibodies) is a critical cofactor for p53 (show TP53 Antibodies)-mediated apoptosis through promoting Tip60 (show KAT5 Antibodies)-mediated p53 (show TP53 Antibodies) acetylation.
We propose that CUL7 (show CUL7 Antibodies), OBSL1 (show OBSL1 Antibodies), and CCDC8 are members of a pathway controlling mammalian growth.
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3).
coiled-coil domain-containing protein 8
, protein phosphatase 1, regulatory subunit 20
, probable Coiled-coil domain-containing protein 8
, coiled-coil domain-containing protein 8 homolog