Protein Summary

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Gene names and symbols associated with COL1A2

• collagen type I alpha 2 chain (COL1A2) antibody
• collagen type I alpha 2 L homeolog (col1a2.L) antibody
• collagen, type I, alpha 2 (Col1a2) antibody
• collagen type I alpha 2 chain (Col1a2) antibody
• collagen, type I, alpha 2 (col1a2) antibody

• AA960264 antibody
• AI325291 antibody
• alpha2(I) antibody
• Col1a-2 antibody
• Cola-2 antibody
• Show all synonym aliases
• Cola2 antibody
• hm:zehn2357 antibody
• OI4 antibody
• oim antibody
• wu:fa98d05 antibody
• wu:fa99g10 antibody
• wu:fb04c08 antibody
• wu:fb11d06 antibody
• zehn2357 antibody

Protein level used designations for COL1A2

procollagen, type I, alpha 2 , alpha 2(I) collagen , alpha-2 type I collagen , alpha-2(1) collagen , collagen alpha 2(I) chain , collagen alpha-2(I) chain , alpha 2(I)-collagen , collagen I, alpha-2 polypeptide , collagen of skin, tendon and bone, alpha-2 chain , type I procollagen , COL1A2 gene exons 8 through 12 , type I procollagen pro-alpha 2 chain , alpha 2(I) procollagen , collagen I alpha-2 polypeptide , collagen COL1A2 , osteogenesis imperfecta , alpha 2 type I collagen , collagen a2(I)