Collagen, Type I, alpha 2 (COL1A2) ELISA Kits

COL1A2 encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Additionally we are shipping Collagen, Type I, alpha 2 Antibodies (125) and Collagen, Type I, alpha 2 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
COL1A2 1278 P08123
COL1A2 12843 Q01149
COL1A2 84352 P02466
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Top Collagen, Type I, alpha 2 ELISA Kits at

Showing 10 out of 78 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 6.3 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests Log in to see 13 to 16 Days
Mouse 0.264 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
Rabbit 0.112 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
Rat 0.65 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Log in to see 13 to 16 Days
Dog 0.126 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
Pig 0.188 ng/mL 0.313-20 ng/mL Typical standard curve 96 Tests Log in to see 12 to 14 Days
Cow 0.105 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 15 to 17 Days
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
Chicken 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
Monkey 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days

Top referenced Collagen, Type I, alpha 2 ELISA Kits

  1. Human COL1A2 ELISA Kit for Sandwich ELISA - ABIN414705 : Okumura, Kay, Nakahara, Hamuro, Kinoshita, Koizumi: Inhibition of TGF-? signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine. in PLoS ONE 2013 (PubMed)
    Show all 3 Pubmed References

More ELISA Kits for Collagen, Type I, alpha 2 Interaction Partners

Human Collagen, Type I, alpha 2 (COL1A2) interaction partners

  1. This study demonstrates that COL1A2, COL6A3, and THBS2 gene silencing inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3K-Akt signaling pathway.

  2. The data independently prove the existence of an unusual phenotype of high bone mass osteogenesis imperfecta caused by a mutation in the procollagen C-propeptide cleavage with a clinically persistent phenotype through adulthood.

  3. the presence or absence of a single cysteine in type-I collagen's C-propeptide domain is a key factor governing the ability of a given collagen polypeptide to stably homotrimerize.

  4. Structural basis of homo- and heterotrimerization of COL1A1/ COL1A2 has been reported.

  5. Osteogenesis imperfecta with ectopic mineralizations in dentin and cementum and a COL1A2 mutation has been reported in a Thai adult patient and his preschool daughter.

  6. Mutations in the COL1A1 and COL1A2 genes associated with osteogenesis imperfecta (OI) types I or III.

  7. This study showed that there is no association of collagen type-(2a) and intracranial aneurysms.

  8. High COL1A2 expression is associated with Gastric Cancer.

  9. The aim of this study is to determine whether EcoRI, Del38 and PvuII polymorphisms of COL1A2 are associated with the development of osteoporosis and osteopenia in post-menopausal Polish women. The analyzed COL1A2 polymorphisms seem to be related to osteoporosis development. The COL1A2 polymorphism may be a genetic risk factor related to the development of osteoporosis.

  10. the efficacy of pamidronate treatment does not seem to be related to the genotype of type I collagen in patients with osteogenesis imperfecta.

  11. COL1A2 gene mutation is associated with osteogenesis imperfecta.

  12. We evaluated the association of a 7-base pair (7-bp) indel polymorphism (rs3917) in the 3'UTR of COL1A2 with the risk of sudden cardiac death in a Chinese population. Our data provided initial evidence that rs3917 was highly relevant to SCD susceptibility, and this indel may become a potential marker for molecular diagnosis and genetic counseling of SCD.

  13. meta-analysis suggests COL1A2 rs42524 is a significant risk factor for Intracranial Aneurysm susceptibility.

  14. mutations of the COL1A1 and COL1A2 genes probably underlie the disease in the four families

  15. By acting probably as a posttranscriptional regulator with a different efficacy on COL2A1 and COL1A2 expression, miR-29b can contribute to the collagens imbalance associated with an abnormal chondrocyte phenotype.

  16. Alterations in the extracellular matrix microenvironment, particularly type I collagen, likely contributes to bladder cancer progression.

  17. High methylation of COL1A2 is associated with head and neck cancer.

  18. a phenotypically distinctive group of OI is caused by a mono-allelic COL1 C-propeptide cleavage site mutations and biallelic BMP1 mutations. The subgroup is characterized by high bone mass and other unique skeletal changes, such as coarse trabeculae, pseudo-fractures, and metaphyseal constriction

  19. Genetic variation in COL1A1 and COL1A2 associated with osteogenesis imperfect in Vietnamese patients.

  20. We conducted a retrospective analysis of data from clinical, laboratory, and radiographic information from children evaluated for child abuse in which molecular testing for COL1A1 and COL1A2 genes was conducted. A total of 43 patients underwent molecular testing for Osteogenesis imperfecta (OI)

Cow (Bovine) Collagen, Type I, alpha 2 (COL1A2) interaction partners

  1. In advanced stage granulomas in Mycobacterium bovis-infected cattle, there was an increase in the expression of type I procollagen

  2. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

Mouse (Murine) Collagen, Type I, alpha 2 (COL1A2) interaction partners

  1. miR-26b-5p interacted with 3'UTRs of Col1a2 and CTGF, and circ_000203 could block the interactions of miR-26b-5p and 3'UTRs of Col1a2 and CTGF.

  2. mouse with a Gly610 to cysteine (Cys) substitution in the procollagen alpha2(I) chain show misfolded procollagen accumulation in the endoplasmic reticulum leads to an unusual form of cell stress.

  3. these results indicate that mutant collagen alpha2(I) chain affects both bone quantity and composition.

  4. Activation of COL1A2 transcription by HIF-1alpha occurred in the absence of hypoxia and is strongly enhanced by TGF-beta signaling.

  5. Identify PDGFRbeta as a driver in activating Akt/mTORC1 nexus for high glucose-mediated expression of collagen I (alpha2) in proximal tubular epithelial cells, which contributes to tubulointerstitial fibrosis in diabetic nephropathy.

  6. Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Ialpha2 expression via miR-342

  7. Type I collagen was highly expressed in the spinal cord during the scar-forming phase and induced astrocytic scar formation via the integrin-N-cadherin pathway.

  8. evidence that FOXL2 modulates Col1a2 transcription through interaction with a response element 65 Kb upstream of the transcription start site

  9. Data indicate that insulin-like growth factor 1 (IGF1) could promote collagen I alpha 2 (COL1A2) expression and osteoblast differentiation in primary pre-osteoblasts by increasing La ribonucleoprotein domain family member 6 (Larp6) expression via a posttranscriptional mechanism.

  10. The phosphorylation sequence matched that targeted by Casein Kinase 2, and inhibition of this kinase activity disrupted the ability of scleraxis to modulate the expression of its target genes while also attenuating TGFbeta-induced expression of type I collagen and myofibroblast phenotype conversion marker genes

  11. Decreased expression of Krox20 in mice causes down-regulation of Col1A2 expression, degeneration of the aortic leaflets and disorganization of the extracellular matrix, causing valvular dysfunction.

  12. Resveratrol effectively inhibits collagen I synthesis in IGF-1-stimulated colonic fibroblasts, partly by inhibiting IGF-1R activation, and SIRT1 is also responsible for the process.

  13. Sp7/Osterix induces the mouse Col1a2 expression via the proximal promoter in osteoblastic cells in association with osteoblast differentiation.

  14. Down-regulation let-7 by transforming growth factor-beta1-induced Lin28 upregulates collagen expression in glomerular mesangial cells from diabetic mice.

  15. Data indicate serine-threonine kinase receptor-associated protein (STRAP) as a novel regulator of the coordinated translation of collagen alpha1(I) and alpha2(I) mRNAs.

  16. collagen 1alpha2 transcription is controlled by wound-associated macrophages during the early stages of skin wound healing

  17. Data show the expression of collagen 1alpha2 of scattered fibroblasts in young rats but not in the kidneys from old rats.

  18. atomistic simulations of a section of mouse type I heterotrimer and homotrimer collagen molecules

  19. The data showed that the Smad pathway mediated the expression of type I collagen in radiation induced fibrosis.

  20. MRTF-A is an important regulator of collagen synthesis in lung fibroblasts and exhibits a dependence on both SRF and Sp1 function to enhance collagen expression

Pig (Porcine) Collagen, Type I, alpha 2 (COL1A2) interaction partners

  1. transcript decreased by 41.9-fold compared with uninjured skin after pressure treatment, whereas a 2.3-fold increase was seen in untreated scars

Zebrafish Collagen, Type I, alpha 2 (COL1A2) interaction partners

  1. ven though in adult bone, skin and scales equal amounts of a1(col1a1a) a2(col1a2) and a3(col1a2)chains are present, the presented data suggest a tissue-specific stoichiometry and/or post-translational modification status for collagen type I

Collagen, Type I, alpha 2 (COL1A2) Antigen Profile

Antigen Summary

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Gene names and symbols associated with COL1A2

  • collagen type I alpha 2 chain (COL1A2) antibody
  • collagen type I alpha 2 L homeolog (col1a2.L) antibody
  • collagen, type I, alpha 2 (Col1a2) antibody
  • collagen type I alpha 2 chain (Col1a2) antibody
  • collagen, type I, alpha 2 (col1a2) antibody
  • AA960264 antibody
  • AI325291 antibody
  • alpha2(I) antibody
  • Col1a-2 antibody
  • Cola-2 antibody
  • Cola2 antibody
  • hm:zehn2357 antibody
  • OI4 antibody
  • oim antibody
  • wu:fa98d05 antibody
  • wu:fa99g10 antibody
  • wu:fb04c08 antibody
  • wu:fb11d06 antibody
  • zehn2357 antibody

Protein level used designations for COL1A2

procollagen, type I, alpha 2 , alpha 2(I) collagen , alpha-2 type I collagen , alpha-2(1) collagen , collagen alpha 2(I) chain , collagen alpha-2(I) chain , alpha 2(I)-collagen , collagen I, alpha-2 polypeptide , collagen of skin, tendon and bone, alpha-2 chain , type I procollagen , COL1A2 gene exons 8 through 12 , type I procollagen pro-alpha 2 chain , alpha 2(I) procollagen , collagen I alpha-2 polypeptide , collagen COL1A2 , osteogenesis imperfecta , alpha 2 type I collagen , collagen a2(I)

100860940 Capra hircus
380419 Xenopus laevis
396243 Gallus gallus
1278 Homo sapiens
403824 Canis lupus familiaris
282188 Bos taurus
100008997 Oryctolagus cuniculus
12843 Mus musculus
84352 Rattus norvegicus
100719158 Cavia porcellus
100626716 Sus scrofa
336471 Danio rerio
100135811 Oncorhynchus mykiss
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