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COL5A2 encodes an alpha chain for one of the low abundance fibrillar collagens. Additionally we are shipping COL5A2 Antibodies (30) and COL5A2 Proteins (5) and many more products for this protein.
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COL5A2(+/-) humans, although unlikely to present with frank classic Ehlers-Danlos syndrome, are likely to have fragile connective tissues with increased susceptibility to trauma and certain chronic pathologic conditions.
data confirm that COL5A1 (show COL5A1 ELISA Kits) and COL5A2 are the major, if not the only, genes involved in classic Ehlers-danlos syndrome
Col5a2 shows predictive potential in myocardial infarction , and in principle may represent a novel candidate marker for the identification and treatment of ischemic cardiovascular disease
study shows that over 90% of patients, which strictly satisfy all major Villefranche criteria for classic Ehlers-Danlos Syndrome (EDS)harbor a type V collagen (show COL5A1 ELISA Kits) defect which indicates that this is the major--if not only--cause of classic EDS
This study suggests a fetal association of COL5A2 and a combined fetal-maternal association of COL5A1 (show COL5A1 ELISA Kits) with spontaneous preterm delivery.
Before but not after developing bronchiolitis obliterans, lung transplantation patients had antibodies to Col (show HDAC1 ELISA Kits)-V, alpha2(V). Pep5 (show VPS11 ELISA Kits)-8 to alpha1,2(V) and pep9-14 to alpha2(V)were immunodominant.
Physical and laboratory examinations revealed that true haploinsufficiency of COL3A1 (show COL3A1 ELISA Kits), COL5A2, and MSTN (show MSTN ELISA Kits), but not that of SLC40A1 (show SLC40A1 ELISA Kits), leads to a clinical phenotype.
Mutations in the COL5A2 gene have been identified by DNA sequence analysis in 10 patients with spontaneous vertebral artery dissections.
analysis of processing of the Pro-alpha1(V)Pro-alpha2(V)Pro-alpha3(V (show COL5A3 ELISA Kits)) procollagen heterotrimer
In the eye, COL5A1 (show COL5A1 ELISA Kits) and COL5A2 mutations manifest as abnormally thin and steep corneas with floppy eyelids.
Col5a2 haploinsufficiency markedly increased the incidence and severity of abdominal aortic aneurysms.
Mice with null alleles for the Col5a2. Col5a2(-/-) homozygosity is embryonic lethal at approximately 12 days post conception.
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.
alpha 2 type V collagen
, collagen alpha-2(V) chain
, collagen, type V, alpha 2
, collagen, type V, alpha-2 chain
, collagen alpha-2(V) chain-like
, AB collagen
, collagen, fetal membrane, A polypeptide
, type V preprocollagen alpha 2 chain
, procollagen, type V, alpha 2
, collagen type V alpha 2