Collagen, Type VI, alpha 3 (COL6a3) ELISA Kits

COL6a3 encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. Additionally we are shipping COL6a3 Antibodies (19) and COL6a3 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse COL6a3 COL6a3 12835  
Anti-Rat COL6a3 COL6a3 367313  
COL6a3 1293 P12111
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Top COL6a3 ELISA Kits at

Showing 7 out of 22 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 50 pg/mL 125 pg/mL - 2000 pg/mL 96 Tests Log in to see 13 to 16 Days
Monkey 18.75 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 12 to 14 Days
Pig 18.75 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 12 to 14 Days
Chicken 0.938 pg/mL 1.563-100 pg/mL   96 Tests Log in to see 12 to 14 Days
Rabbit 0.75 pg/mL 1.25-80 pg/mL   96 Tests Log in to see 12 to 14 Days
Guinea Pig 0.938 pg/mL 1.563-100 pg/mL   96 Tests Log in to see 12 to 14 Days
Sheep 9.375 pg/mL 15.625 pg/mL - 1000 pg/mL   96 Tests Log in to see 11 to 18 Days

Top referenced COL6a3 ELISA Kits

  1. Human COL6a3 ELISA Kit for Sandwich ELISA - ABIN417870 : Kang, Wang, Axell-House, Soni, Chu, Chipitsyna, Sarosiek, Sendecki, Hyslop, Al-Zoubi, Yeo, Arafat: Clinical significance of serum COL6A3 in pancreatic ductal adenocarcinoma. in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2014 (PubMed)
    Show all 2 Pubmed References

More ELISA Kits for COL6a3 Interaction Partners

Mouse (Murine) Collagen, Type VI, alpha 3 (COL6a3) interaction partners

  1. Overexpression of endotrophin caused upregulation of adipogenic genes in the white adipose tissue(WAT) of endotrophin transgenic mice. The mice exhibited inhibited lipolysis and accelerated hypertrophy and hyperplasia in WAT.

  2. Data indicate that overexpression of endotrophin (COL6alpha3) locally in adipose tissue promotes metabolic dysfunction under a high-fat diet (HFD) challenge.

  3. Data show that the TFIID subunit TAF4 is essential to restrain the growth promoting properties of collagen 6A3 (Col6a3).

  4. mice lacking normal alpha3(VI) collagen chains display mild musculoskeletal phenotypes similar to mice deficient in the alpha1(VI) collagen alpha chain, suggesting that alpha3(VI) collagen does not elicit essential functions in normal growth and development

  5. analysis of collagen VI chains alpha4, alpha5, and alpha6with high homology to the alpha3 chain

Human Collagen, Type VI, alpha 3 (COL6a3) interaction partners

  1. Altered white matter structure especially in various parts of the cerebello-thalamo-cortical network in dystonia patients with COL6A3 mutations.

  2. This study demonstrates that COL1A2, COL6A3, and THBS2 gene silencing inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3K-Akt signaling pathway.

  3. COL6A3 could influence the viability and angiogenesis of bladder cancer cells. COL6A3 may have a certain relationship with the TGF-beta/Smad-induced EMT process.

  4. The morphology and immunophenotype of all 6 cases was analogous to those with the canonical COL1A1-PDGFB fusion; none of the cases showed fibrosarcomatous transformation. This study illustrates that the COL6A3-PDGFD fusion product is rare in dermatofibrosarcoma protuberans, and associated with an apparent predilection for breast

  5. Study found COL6A3 expression to be downregulated and associated with poor prognosis in human colorectal cancer (CRC). In silico analysis of cell typespecific gene expression and COL6A3 knockout experiments indicated the clinical relevance of COL6A3 in the development of CRC.

  6. COL6A mutation Congenital Muscular Dystrophy showed the muscle weakness and poor respiratory function.

  7. two compound heterozygous mutations in COL6A3 gene lead to myopathy from Ullrich congenital muscular dystrophy and Bethlem myopathy spectrum.

  8. COL6A3-associated dystonia represents a newly identified autosomal-recessive entity characterized clinically by an early symptom onset with variable distribution.

  9. Overexpression of endotrophin led to a fibrotic program in white adipose tissue (WAT) adipocytes, a proinflammatory program in (WAT) macrophages, and upregulation of both profibrotic and proinflammatory genes in the stromal vascular fraction isolated from WAT.

  10. Patients with chronic kidney disease (CKD) are at increased risk of end-stage renal disease (ESRD) and early mortality. Serum endotrophin, a COL6A3 cleavage product was significantly associated with progression to ESRD.

  11. In conjunction with the relatively high frequency of homozygous carriers of reported mutations in publically available databases, our data call a causal role for variants in COL6A3 in isolated dystonia into question.

  12. Data indicate that circulating plasma COL6A3 in colorectal cancer (CRC) patients was upregulated significantly comparing with healthy peoples.

  13. COL6A mutations were identified in eight cases having clinical phenotypes of Ullrich congenital muscular dystrophy (UCMD) or Bethlem myopathy (BM).

  14. Parental mosaicism was confirmed in the four families through quantitative analysis of the ratio of mutant versus wild-type allele (COL6A1, COL6A2, and COL6A3) in genomic DNA from various tissues; consistent with somatic mosaicism, parental samples had lower ratios of mutant versus wild-type allele compared with the fully heterozygote offspring.

  15. Recessive mutations in the alpha3 (VI) collagen gene COL6A3 cause early-onset isolated dystonia.

  16. Increased adipocyte COL6A3 expression associates with insulin resistance; COL6A3 mRNA associates with small adipocyte size

  17. The heterozygous c.3353A>C mutation in exon 8 of the COL6A3 gene is associated with the Bethlem myopathy with autosomal dominant inheritance.

  18. This study showed that COL6A3 expression appeared to be lowered in obesity, whereas diet- and surgery-induced weight loss increased COL6A3 expression.

  19. In UCMD, 1 mutation was indentified in Chinese patients.

  20. Data indicate that endotrophin (COL6alpha3) levels are higher in diabetic patients.

COL6a3 Antigen Profile

Antigen Summary

This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described.

Gene names and symbols associated with COL6a3

  • collagen type VI alpha 3 chain (COL6A3) antibody
  • collagen, type VI, alpha 3 (col6a3) antibody
  • collagen, type VI, alpha 3 (Col6a3) antibody
  • collagen type VI alpha 3 chain (Col6a3) antibody
  • AI507288 antibody
  • Col6a-3 antibody
  • COL6A3 antibody
  • wu:fb06e12 antibody
  • wu:fs74g09 antibody

Protein level used designations for COL6a3

collagen alpha-3(VI) chain , type VI collagen alpha 3 chain , alpha 3 type VI collagen , collagen, type VI, alpha 3 , collagen alpha-3(VI) chain-like , collagen alpha 3 chain type VI , collagen alpha3(VI) , procollagen, type VI, alpha 3 , type VI collagen alpha 3 subunit , collagen VI, alpha-3 polypeptide , alpha-3 collagen type VI , collagen type VI alpha 3

403582 Canis lupus familiaris
460045 Pan troglodytes
530657 Bos taurus
556874 Danio rerio
694701 Macaca mulatta
100459849 Pongo abelii
100465530 Ailuropoda melanoleuca
12835 Mus musculus
367313 Rattus norvegicus
1293 Homo sapiens
396548 Gallus gallus
100101551 Sus scrofa
100716662 Cavia porcellus
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